Friday, July 10, 2026

Drug profile · INN

doxycycline hyclate

doxycycline hyclate (DOXYCYCLINE HYCLATE) is a matrix metalloproteinase-1 inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 5
Pipeline programs 18
News articles 0
Drug details — doxycycline hyclate
US status
approved
Class
Route
INJECTION
Patents
5
Programs
18
Data quality
0.89

Quick answer

doxycycline hyclate (DOXYCYCLINE HYCLATE) is a matrix metalloproteinase-1 inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN doxycycline hyclate
Brand DOXYCYCLINE HYCLATE
Mechanism Matrix metalloproteinase-1 inhibitor
Target Bacterial 70S ribosome
Route INJECTION
Formulation CAPSULE, COATED PELLETS

Mechanism of action

Matrix metalloproteinase-1 inhibitor

Primary target: Bacterial 70S ribosome

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. APHP180588 Phase 3 · PARItec · early syphilis
  2. APHP220763 Phase 3 · PARItec · Catheter related bloodstream infections due to Staphylococcu
  3. AUTOP 2 Phase 3 · Ishita Pharma - · Bacterial vaginosis, High risk preterm birth pregnancy, Vagi
  4. Doxy-WISE Phase 3 · George Institute for · Sexually Transmitted Infections
  5. Doxycycline Phase 3 · Hospital Authority · Tuberculosis
  6. Doxycycline Phase 3 · United Therapeutics Europe · Lymphedema
  7. Doxycycline (200mg/day) or Placebo Phase 3 · United Therapeutics Europe · Persian Gulf Syndrome
  8. Placebo capsules for bacterial sexually transmitted… Phase 3 · George Institute for · bacterial sexually transmitted infections

Related & competitor drugs

  1. azithromycin Bacterial 70S ribosome inhibitor
  2. chloramphenicol Bacterial 70S ribosome inhibitor
  3. clarithromycin Bacterial 70S ribosome inhibitor
  4. clindamycin hydrochloride Bacterial 70S ribosome inhibitor
  5. clindamycin palmitate hydrochloride Bacterial 70S ribosome inhibitor
  6. clindamycin phosphate Bacterial 70S ribosome inhibitor
  1. US 11219631

    Foamable compositions, breakable foams and their uses

    Expires Mon Jan 06 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11103454

    Wax foamable vehicle and pharmaceutical compositions thereof

    Expires Mon Aug 26 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11033491

    Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

    Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8652516

    Doxycycline formulations, and methods of treating rosacea

    Expires Mon Feb 13 2034 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7749532

    Once daily formulations of tetracyclines

    Expires Mon Jul 01 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is doxycycline hyclate?

doxycycline hyclate (DOXYCYCLINE HYCLATE) is a matrix metalloproteinase-1 inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for doxycycline hyclate?

DOXYCYCLINE HYCLATE is a marketed brand name for doxycycline hyclate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of doxycycline hyclate?

doxycycline hyclate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.