Wednesday, July 8, 2026

Drug profile · INN

doxycycline

doxycycline (APX-DOXYCYCLINE) is a matrix metalloproteinase 8 inhibitor. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved TGA: approved NMPA: clinical trials
US status approved
Patents linked 1
Pipeline programs 5
News articles 0
Drug details — doxycycline
US status
approved
Class
Route
ORAL
Patents
1
Programs
5
Data quality
0.89

Quick answer

doxycycline (APX-DOXYCYCLINE) is a matrix metalloproteinase 8 inhibitor. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN doxycycline
Brand APX-DOXYCYCLINE
Mechanism Matrix metalloproteinase 8 inhibitor
Target Bacterial 70S ribosome
Route ORAL
Formulation FOR SUSPENSION

Mechanism of action

Matrix metalloproteinase 8 inhibitor

Primary target: Bacterial 70S ribosome

Approval history

Authority Status Date
FDA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. APHP180588 Phase 3 · PARItec · early syphilis
  2. Doxy-WISE Phase 3 · George Institute for · Sexually Transmitted Infections
  3. Doxycycline Phase 3 · Hospital Authority · Tuberculosis
  4. Doxycycline Phase 2 · Hospital Authority · Tuberculosis, Meningeal
  5. Doxycycline Unknown · LianBio · Amyloidosis; Systemic

Related & competitor drugs

  1. azithromycin Bacterial 70S ribosome inhibitor
  2. chloramphenicol Bacterial 70S ribosome inhibitor
  3. clarithromycin Bacterial 70S ribosome inhibitor
  4. clindamycin hydrochloride Bacterial 70S ribosome inhibitor
  5. clindamycin palmitate hydrochloride Bacterial 70S ribosome inhibitor
  6. clindamycin phosphate Bacterial 70S ribosome inhibitor
  1. US 7749532

    Once daily formulations of tetracyclines

    Expires Mon Jul 01 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is doxycycline?

doxycycline (APX-DOXYCYCLINE) is a matrix metalloproteinase 8 inhibitor. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for doxycycline?

APX-DOXYCYCLINE is a marketed brand name for doxycycline. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of doxycycline?

doxycycline has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.