Friday, July 10, 2026

Drug profile · INN

dostarlimab

dostarlimab (JEMPERLI) is a programmed cell death protein 1 antagonist. Associated with GlaxoSmithKline.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01FF07
Patents linked 0
Pipeline programs 26
News articles 0
Drug details — dostarlimab
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
26
Data quality
0.83

Quick answer

dostarlimab (JEMPERLI) is a programmed cell death protein 1 antagonist. Associated with GlaxoSmithKline.

Key facts

INN dostarlimab
Brand JEMPERLI
Mechanism Programmed cell death protein 1 antagonist
Target Programmed cell death protein 1
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FF07

Mechanism of action

Programmed cell death protein 1 antagonist

Primary target: Programmed cell death protein 1

Approval history

Authority Status Date
EMA approved
TGA approved

Pipeline programs

  1. 213350/3000-03-005 Phase 3 · TESARO Bio Netherlands · Stage 3 or 4 Non-mucinous Epithelial Ovarian Cancer
  2. 213410 Phase 3 · GSK Glaxo Smith · Lung Cancer, Non-Small Cell
  3. 213823 Phase 3 · GSK Glaxo Smith · Lung Cancer, Non-Small Cell
  4. 221530 Phase 3 · GSK Glaxo Smith · Neoplasms, Head and Neck
  5. 4010-03-001 Phase 3 · TESARO Bio Netherlands · Recurrent or primary advanced (Stage III or IV) endometrial
  6. Dostarlimab Phase 3 · GSK Glaxo Smith · Neoplasms, Head and Neck
  7. MITO 33 Phase 3 · Telethon Foundation · Recurrent ovarian, fallopian tube or primary peritoneal canc
  8. UC-IMM-2101 Phase 3 · Ningbo Cancer Hospital · Only patients with oncologic locally advanced or metastatic

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is dostarlimab?

dostarlimab (JEMPERLI) is a programmed cell death protein 1 antagonist. Associated with GlaxoSmithKline.

What is the brand name for dostarlimab?

JEMPERLI is a marketed brand name for dostarlimab. Check FDA Drugs@FDA for the current US label holder and prescribing information.