Wednesday, July 8, 2026

Drug profile · INN

dexmedetomidine hydrochloride

dexmedetomidine hydrochloride (PRECEDEX PARTIAL CHANGE APPROVAL) is a adrenergic receptor alpha-2 agonist. Associated with Regeneron Ireland Designated Activity Company (DAC). Route of administration: buccal, sublingual. Current US regulatory status: approved.

FDA: approved PMDA: approved
US status approved
Patents linked 14
Pipeline programs 33
News articles 0
Drug details — dexmedetomidine hydrochloride
US status
approved
Class
Route
BUCCAL, SUBLINGUAL
Patents
14
Programs
33
Data quality
0.89

Quick answer

dexmedetomidine hydrochloride (PRECEDEX PARTIAL CHANGE APPROVAL) is a adrenergic receptor alpha-2 agonist. Associated with Regeneron Ireland Designated Activity Company (DAC). Route of administration: buccal, sublingual. Current US regulatory status: approved.

Key facts

INN dexmedetomidine hydrochloride
Brand PRECEDEX PARTIAL CHANGE APPROVAL
Mechanism Adrenergic receptor alpha-2 agonist
Target Adrenergic receptor alpha-2
Route BUCCAL, SUBLINGUAL
Formulation INJECTABLE

Mechanism of action

Adrenergic receptor alpha-2 agonist

Primary target: Adrenergic receptor alpha-2

Approval history

Authority Status Date
FDA approved
PMDA approved

Pipeline programs

  1. SEVOFLURANE, DEXMEDETOMIDINE HYDROCHLORIDE Phase 3 · George Institute for · Children under the age of 2 years having surgery lasting at
  2. Dexmedetomidine Phase 2 · Cognition Therapeutics · Alzheimer Disease
  3. Dexmedetomidine Phase 2 · BioXcel Therapeutics · Opioid Withdrawal
  4. Dexmedetomidine Phase 1 · First People's Hospital · Cesarean Section, Affecting Fetus or Newborn
  5. Dexmedetomidine Phase 1 · First People's Hospital · Heart Injuries
  6. Dexmedetomidine Approved · Chinese Academy of · Chronic Post-Surgical Pain
  7. Dexmedetomidine Approved · United Therapeutics Europe · Breast Cancer
  8. Dexmedetomidine Approved · Chinese Academy of · Lower Limb Fracture

Related & competitor drugs

  1. brimonidine tartrate Adrenergic receptor alpha-2 agonist
  2. clonidine hydrochloride Adrenergic receptor alpha-2 agonist
  3. guanfacine hydrochloride Adrenergic receptor alpha-2 agonist
  4. methyldopa Adrenergic receptor alpha-2 agonist
  5. methyldopate hydrochloride Adrenergic receptor alpha-2 agonist
  6. mirtazapine Serotonin 2a (5-HT2a) receptor antagonist
  1. US 12364683

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon Jul 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12138247

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon Nov 07 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12109196

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon Oct 03 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12090140

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon Sep 12 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11998529

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11998528

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11890272

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon Feb 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11839604

    Use of sublingual dexmedetomidine for the treatment of agitation

    Expires Mon Dec 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11806334

    Non-sedating dexmedetomidine treatment regimens

    Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11786508

    Use of sublingual dexmedetomidine for the treatment of agitation

    Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11517524

    Film formulations containing dexmedetomidine and methods of producing them

    Expires Mon Dec 01 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11497711

    Film formulations containing dexmedetomidine and methods of producing them

    Expires Mon Nov 10 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11478422

    Film formulations containing dexmedetomidine and methods of producing them

    Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10792246

    Film formulations containing dexmedetomidine and methods of producing them

    Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is dexmedetomidine hydrochloride?

dexmedetomidine hydrochloride (PRECEDEX PARTIAL CHANGE APPROVAL) is a adrenergic receptor alpha-2 agonist. Associated with Regeneron Ireland Designated Activity Company (DAC). Route of administration: buccal, sublingual. Current US regulatory status: approved.

What is the brand name for dexmedetomidine hydrochloride?

PRECEDEX PARTIAL CHANGE APPROVAL is a marketed brand name for dexmedetomidine hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of dexmedetomidine hydrochloride?

dexmedetomidine hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.