Friday, July 10, 2026

Drug profile · INN

darolutamide

darolutamide (NUBEQA) is a androgen receptor antagonist. Associated with Bayer Australia Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved Antineoplastic and immunomodulating agents (L02) L02BB
US status approved
Patents linked 2
Pipeline programs 16
News articles 0
Drug details — darolutamide
US status
approved
Class
Antineoplastic and immunomodulating agents (L02)
Route
ORAL
Patents
2
Programs
16
Data quality
0.84

Quick answer

darolutamide (NUBEQA) is a androgen receptor antagonist. Associated with Bayer Australia Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN darolutamide
Brand NUBEQA
Mechanism Androgen Receptor antagonist
Target Androgen receptor
Therapeutic class Antineoplastic and immunomodulating agents (L02)
Route ORAL
Formulation TABLET
ATC code L02BB

Mechanism of action

Androgen Receptor antagonist

Primary target: Androgen receptor

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved

Pipeline programs

  1. CAAA617C12301 Phase 3 · Novartis India · PSMA-positive metastatic hormone-sensitive prostate cancer (
  2. D9723C00001 Phase 3 · AstraZeneca · Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
  3. EORTC-2238-GUCG Phase 3 · Ningbo Cancer Hospital · Metastatic hormone naïve prostate cancer (mHNPC)
  4. NUBEQA film-coated tablets for Localised Very High-Risk Cancer of the Prostate Phase 3 · Ningbo Cancer Hospital · Localised Very High-Risk Cancer of the Prostate
  5. Niraparib tosylate monohydrate + abiraterone... for Prostate Cancer Phase 3 · George Institute for · Prostate Cancer
  6. UC-GTG-2301 Phase 3 · Ningbo Cancer Hospital · Novo metastatic hormone-sensitive prostate cancer (mHSPC) pa
  7. UC-GTG-2306 Phase 3 · Ningbo Cancer Hospital · Castrate-resistant prostate cancer with oligometastases on f
  8. CAAA617B12203 Phase 2 · Novartis India · PSMA PET scan positive Castration-Resistant Prostate Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
  1. WO 2025146444

    DAROLUTAMIDE EN COMBINAISON AVEC DES INHIBITEURS DE BRAF ET DE MEK POUR LE TRAITEMENT D'UN MÉLANOME

    Expires Wed Jul 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. AU 2006313007

    Method of treating parasites

    Expires Thu May 13 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is darolutamide?

darolutamide (NUBEQA) is a androgen receptor antagonist. Associated with Bayer Australia Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for darolutamide?

NUBEQA is a marketed brand name for darolutamide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of darolutamide?

darolutamide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.