Wednesday, July 8, 2026

Drug profile · INN

daprodustat

daprodustat (JESDUVROQ) is a hypoxia-inducible factor prolyl hydroxylase inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: application withdrawn Blood and blood forming organs (B03) B03XA
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — daprodustat
US status
approved
Class
Blood and blood forming organs (B03)
Route
ORAL
Patents
0
Programs
2
Data quality
0.84

Quick answer

daprodustat (JESDUVROQ) is a hypoxia-inducible factor prolyl hydroxylase inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN daprodustat
Brand JESDUVROQ
Mechanism Hypoxia-inducible factor prolyl hydroxylase inhibitor
Target Hypoxia-inducible factor prolyl hydroxylase
Therapeutic class Blood and blood forming organs (B03)
Route ORAL
Formulation TABLET
ATC code B03XA

Mechanism of action

Hypoxia-inducible factor prolyl hydroxylase inhibitor

Primary target: Hypoxia-inducible factor prolyl hydroxylase

Approval history

Authority Status Date
FDA approved
EMA application withdrawn

Pipeline programs

  1. IST-342 Phase 2 · Karyopharm Therapeutics · Relapsed Multiple Myeloma
  2. Daprodustat 2 mg tablet Phase 1 · GSK Glaxo Smith · Anaemia

Related & competitor drugs

  1. apixaban Blood and blood forming organs (B01)
  2. berotralstat Blood and blood forming organs (B06)
  3. bivalirudin Blood and blood forming organs (B01)
  4. c1 inhibitor (human) Blood and blood forming organs (B06)
  5. clopidogrel Blood and blood forming organs (B01)
  6. dabigatran etexilate Blood and blood forming organs (B01)

Frequently asked questions

What is daprodustat?

daprodustat (JESDUVROQ) is a hypoxia-inducible factor prolyl hydroxylase inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for daprodustat?

JESDUVROQ is a marketed brand name for daprodustat. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of daprodustat?

daprodustat has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.