Friday, July 10, 2026

Drug profile · INN

crovalimab

crovalimab (PIASKY) is a complement c5 inhibitor.

EMA: approved PMDA: approved Antineoplastic and immunomodulating agents (L04) L04AJ07
Patents linked 0
Pipeline programs 6
News articles 0
Drug details — crovalimab
Class
Antineoplastic and immunomodulating agents (L04)
Route
Patents
0
Programs
6
Data quality
0.83

Quick answer

crovalimab (PIASKY) is a complement c5 inhibitor.

Key facts

INN crovalimab
Brand PIASKY
Mechanism Complement C5 inhibitor
Target Complement C5
Therapeutic class Antineoplastic and immunomodulating agents (L04)
ATC code L04AJ07

Mechanism of action

Complement C5 inhibitor

Primary target: Complement C5

Approval history

Authority Status Date
EMA approved
PMDA approved

Pipeline programs

  1. BO42161 Phase 3 · HOFFMANN-LA ROCHE · Paroxysmal Nocturnal Hemoglobinuria (PNH)
  2. BO42162 Phase 3 · HOFFMANN-LA ROCHE · Paroxysmal Nocturnal Hemoglobinuria (PNH)
  3. Crovalimab Phase 3 · HOFFMANN-LA ROCHE · Paroxysmal Nocturnal Hemoglobinuria
  4. Crovalimab Phase 3 · HOFFMANN-LA ROCHE · Atypical Hemolytic Uremic Syndrome (aHUS)
  5. Crovalimab, Crovalimab Phase 3 · HOFFMANN-LA ROCHE · Atypical Hemolytic Uremic Syndrome (aHUS)
  6. BP39144 Phase 2 · HOFFMANN-LA ROCHE · Paroxysmal nocturnal hemoglobinuria (PNH)

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is crovalimab?

crovalimab (PIASKY) is a complement c5 inhibitor.

What is the brand name for crovalimab?

PIASKY is a marketed brand name for crovalimab. Check FDA Drugs@FDA for the current US label holder and prescribing information.