Wednesday, July 8, 2026

Drug profile · INN

crinecerfont

crinecerfont (CRENESSITY) is a corticotropin releasing factor receptor 1 antagonist. Associated with NEUROCRINE BIOSCIENCES INC. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 8
Pipeline programs 4
News articles 0
Drug details — crinecerfont
US status
approved
Class
Route
ORAL
Patents
8
Programs
4
Data quality
0.89

Quick answer

crinecerfont (CRENESSITY) is a corticotropin releasing factor receptor 1 antagonist. Associated with NEUROCRINE BIOSCIENCES INC. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN crinecerfont
Brand CRENESSITY
Mechanism Corticotropin releasing factor receptor 1 antagonist
Target Corticotropin-releasing factor receptor 1
Route ORAL
Formulation CAPSULE

Mechanism of action

Corticotropin releasing factor receptor 1 antagonist

Primary target: Corticotropin-releasing factor receptor 1

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Crinecerfont Phase 3 · NEUROCRINE BIOSCIENCES · Congenital Adrenal Hyperplasia
  2. NBI-74788-CAH2006 Phase 3 · NEUROCRINE BIOSCIENCES · Classic Congenital Adrenal Hyperplasia (CAH)
  3. NBI-74788-CAH3003 Phase 3 · NEUROCRINE BIOSCIENCES · Classic Congenital Adrenal Hyperplasia (CAH)
  4. Crinecerfont Phase 2 · NEUROCRINE BIOSCIENCES · CAH - Congenital Adrenal Hyperplasia
  1. US 12421193

    GPR52 modulators and methods of use

    Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12128033

    Synthetic methods for preparation of 4-(2-chloro-4-methoxy-5-methylphenyl)-n-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-n-prop-2-ynyl-1,3-thiazol-2-amine

    Expires Mon Oct 24 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11730739

    Treatment of congenital adrenal hyperplasia

    Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11311544

    Treatment of congenital adrenal hyperplasia

    Expires Mon Apr 21 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10905690

    Treatment of congenital adrenal hyperplasia

    Expires Mon Jan 28 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 6469166

    Thiophenopyrimidines

    Expires Mon Oct 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  7. US 6288060

    Amino substituted pyrimidines and triazines

    Expires Mon Sep 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  8. US 6255310

    Thiophenopyrimidines

    Expires Mon Jun 28 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is crinecerfont?

crinecerfont (CRENESSITY) is a corticotropin releasing factor receptor 1 antagonist. Associated with NEUROCRINE BIOSCIENCES INC. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for crinecerfont?

CRENESSITY is a marketed brand name for crinecerfont. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of crinecerfont?

crinecerfont has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.