Wednesday, July 8, 2026

Drug profile · INN

corticotropin

corticotropin (PURIFIED CORTROPHIN GEL) is a melanocortin receptor 2 agonist. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 20
Pipeline programs 4
News articles 0
Drug details — corticotropin
US status
approved
Class
Route
INJECTION
Patents
20
Programs
4
Data quality
0.84

Quick answer

corticotropin (PURIFIED CORTROPHIN GEL) is a melanocortin receptor 2 agonist. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN corticotropin
Brand PURIFIED CORTROPHIN GEL
Mechanism Melanocortin receptor 2 agonist
Target Adrenocorticotropic hormone receptor
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Melanocortin receptor 2 agonist

Primary target: Adrenocorticotropic hormone receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. FET Phase 3 · Disc Medicine · ACTH-dependent hypercortisolism
  2. MLS-101-301 Phase 3 · Mineralys Therapeutics · Uncontrolled and Resistant Hypertension
  3. MLS-101-901 Phase 3 · Mineralys Therapeutics · Hypertension
  4. Synacthen (Tetracosactrin) Approved · Cardiff Oncology · Healthy

Related & competitor drugs

  1. cosyntropin Melanocortin receptor 2 agonist
  2. corticotropin-zinc hydroxide Melanocortin receptor 2 agonist
  3. repository corticotropin Melanocortin receptor 2 agonist
  4. tetracosactide Melanocortin receptor 2 agonist

Related patents

  1. US 12324787

    Kits for preparing and delivering purified corticotropin

    Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12233105

    Methods for storing and warming purified corticotropin compositions

    Expires Mon Feb 20 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12133831

    Kits for preparing and delivering purified corticotropin

    Expires Mon Oct 31 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12115166

    Corticotropin releasing factor receptor antagonists

    Expires Mon Oct 10 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12102662

    Methods for storing and warming purified corticotropin compositions

    Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11975047

    Methods for storing and warming purified corticotropin compositions

    Expires Mon May 02 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11351177

    Corticotropin releasing factor receptor antagonists

    Expires Mon Jun 02 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11344557

    Corticotropin releasing factor receptor antagonists

    Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11311549

    Corticotropin releasing factor receptor antagonists

    Expires Mon Apr 21 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11202787

    Use of ACTH in assessment and prophylactic treatment of hypokalemia associated with glucocorticoid receptor modulator treatment of Cushing's syndrome patients

    Expires Mon Dec 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11077108

    Allosteric corticotropin-releasing factor receptor 1 (CRFR1) antagonists that decrease p-tau and improve cognition

    Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11007201

    Corticotropin releasing factor receptor antagonists

    Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10849908

    Corticotropin releasing factor receptor antagonists

    Expires Mon Nov 26 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10314850

    Use of ACTH in assessment and prophylactic treatment of hypokalemia associated with glucocorticoid receptor modulator treatment of Cushing's syndrome patients

    Expires Mon Jun 06 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10231983

    Use of ACTH in assessment and prophylactic treatment of hypokalemia associated with glucocorticoid receptor modulator treatment of Cushing's syndrome patients

    Expires Mon Mar 14 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8901141

    Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them

    Expires Mon Nov 27 2034 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7285534

    Corticotropin-releasing hormone analogs and their uses

    Expires Mon Oct 18 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7034118

    Corticotropin-releasing factor2 receptors

    Expires Mon Apr 20 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  19. US 6803359

    Inhibition of abnormal cell growth with corticotropin-releasing hormone analogs

    Expires Mon Oct 07 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  20. US 6723841

    Corticotropin-releasing factor2 receptors

    Expires Mon Apr 15 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is corticotropin?

corticotropin (PURIFIED CORTROPHIN GEL) is a melanocortin receptor 2 agonist. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for corticotropin?

PURIFIED CORTROPHIN GEL is a marketed brand name for corticotropin. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of corticotropin?

corticotropin has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.