Saturday, July 11, 2026

Drug profile · INN

ciltacabtagene autoleucel

ciltacabtagene autoleucel (CARVYKTI) is a tumor necrosis factor receptor superfamily member 17 binding agent.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01XL05
Patents linked 0
Pipeline programs 5
News articles 2
Drug details — ciltacabtagene autoleucel

Quick answer

ciltacabtagene autoleucel (CARVYKTI) is a tumor necrosis factor receptor superfamily member 17 binding agent.

Key facts

INN ciltacabtagene autoleucel
Brand CARVYKTI
Mechanism Tumor necrosis factor receptor superfamily member 17 binding agent
Target Tumor necrosis factor receptor superfamily member 17
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XL05

Mechanism of action

Tumor necrosis factor receptor superfamily member 17 binding agent

Primary target: Tumor necrosis factor receptor superfamily member 17

Approval history

Authority Status Date
EMA approved

Recent coverage

Pipeline programs

  1. 68284528MMY3002 Phase 3 · Janssen-Cilag International N.V · Relapsed and Lenalidomide-Refractory Multiple Myeloma
  2. 68284528MMY3004 Phase 3 · Janssen-Cilag International N.V · Multiple Myeloma
  3. Cilta-cel Phase 3 · Janssen Cilag International · Multiple Myeloma
  4. 54767414MMY2093 Phase 2 · Janssen-Cilag International N.V · Multiple Myeloma
  5. 68284528MMY2012 Phase 2 · Janssen-Cilag International N.V · Newly Diagnosed Multiple Myeloma

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is ciltacabtagene autoleucel?

ciltacabtagene autoleucel (CARVYKTI) is a tumor necrosis factor receptor superfamily member 17 binding agent.

What is the brand name for ciltacabtagene autoleucel?

CARVYKTI is a marketed brand name for ciltacabtagene autoleucel. Check FDA Drugs@FDA for the current US label holder and prescribing information.