Wednesday, July 8, 2026

Drug profile · INN

chlorotrianisene

chlorotrianisene (TACE) is a estrogen receptor beta modulator. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 7
Pipeline programs 7
News articles 0
Drug details — chlorotrianisene
US status
approved
Class
Route
ORAL
Patents
7
Programs
7
Data quality
0.84

Quick answer

chlorotrianisene (TACE) is a estrogen receptor beta modulator. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN chlorotrianisene
Brand TACE
Mechanism Estrogen receptor beta modulator
Target Estrogen receptor beta
Route ORAL
Formulation CAPSULE

Mechanism of action

Estrogen receptor beta modulator

Primary target: Estrogen receptor beta

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Abatacept s.c. Phase 2 · First People's Hospital · Abatacept
  2. DEB-TACE+HAIC Phase 2 · Chinese Academy of · Hepatocellular Carcinoma Non-resectable
  3. LEN+SIN+DEB-TACE+HAIC Phase 2 · Chinese Academy of · Hepatocellular Carcinoma Non-resectable
  4. NestaCell® Phase 2 · Vera Therapeutics · COVID-19 Pneumonia
  5. TACE and HAIC Combined With Regorafenib Phase 2 · First People's Hospital · Liver Metastasis Colon Cancer
  6. TACE with adebrelimab and bevacizumab Phase 2 · First People's Hospital · Adebrelimab
  7. Epirubicin Approved · Chinese Academy of · Carcinoma, Hepatocellular

Related & competitor drugs

  1. raloxifene hydrochloride Estrogen receptor beta modulator

Related patents

  1. US 9346866

    Inhibition of tace activity with cyclic peptides

    Expires Mon May 19 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8168588

    Compositions comprising FGF-9 and betacellulin and methods for treating cardiac conditions

    Expires Mon Apr 26 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7919520

    Inhibitors of tace

    Expires Mon Mar 31 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7485664

    Inhibitors of TACE

    Expires Mon Jan 29 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 6825165

    Betacellulin modification

    Expires Mon Nov 25 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  6. US 6183971

    Human betacellulin-specific antibodies and uses thereof

    Expires Mon Feb 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  7. US 6090366

    Process for the preparation of an organ-specific substace labeled with technetium-99m

    Expires Mon Jul 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is chlorotrianisene?

chlorotrianisene (TACE) is a estrogen receptor beta modulator. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for chlorotrianisene?

TACE is a marketed brand name for chlorotrianisene. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of chlorotrianisene?

chlorotrianisene has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.