Wednesday, July 8, 2026

Drug profile · INN

cenobamate

cenobamate (ONTOZRY) is a gaba-a receptor; anion channel positive allosteric modulator. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved Nervous system (N03) N03AX
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — cenobamate
US status
approved
Class
Nervous system (N03)
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

cenobamate (ONTOZRY) is a gaba-a receptor; anion channel positive allosteric modulator. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN cenobamate
Brand ONTOZRY
Mechanism GABA-A receptor; anion channel positive allosteric modulator
Target GABA-A receptor; anion channel
Therapeutic class Nervous system (N03)
Route ORAL
Formulation TABLET
ATC code N03AX

Mechanism of action

GABA-A receptor; anion channel positive allosteric modulator

Primary target: GABA-A receptor; anion channel

Approval history

Authority Status Date
FDA approved
EMA approved

Related & competitor drugs

  1. acamprosate calcium GABA-A receptor; anion channel positive modulator
  2. alprazolam GABA-A receptor; anion channel positive allosteric modulator
  3. aripiprazole Nervous system (N05)
  4. brexpiprazole Nervous system (N05)
  5. brivaracetam Nervous system (N03)
  6. bupivacaine Nervous system (N01)

Frequently asked questions

What is cenobamate?

cenobamate (ONTOZRY) is a gaba-a receptor; anion channel positive allosteric modulator. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for cenobamate?

ONTOZRY is a marketed brand name for cenobamate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of cenobamate?

cenobamate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.