Wednesday, July 8, 2026

Drug profile · INN

calcium oxybate

calcium oxybate (XYWAV) is a gaba-b receptor agonist. Associated with Jazz Pharmaceuticals Ireland Limited. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 20
Pipeline programs 1
News articles 0
Drug details — calcium oxybate
US status
approved
Class
Route
ORAL
Patents
20
Programs
1
Data quality
0.89

Quick answer

calcium oxybate (XYWAV) is a gaba-b receptor agonist. Associated with Jazz Pharmaceuticals Ireland Limited. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN calcium oxybate
Brand XYWAV
Mechanism GABA-B receptor agonist
Target GABA-B receptor
Route ORAL
Formulation SOLUTION

Mechanism of action

GABA-B receptor agonist

Primary target: GABA-B receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. JZP258 (XYWAV) Approved · Jazz Pharmaceuticals Ireland · Idiopathic Hypersomnia

Related & competitor drugs

  1. baclofen GABA-B receptor agonist
  2. sodium oxybate Nervous system (N07)
  1. US 12138233

    Methods of treating idiopathic hypersomnia

    Expires Mon Nov 07 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11986446

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11554102

    Gamma-hydroxybutyrate compositions and their uses for the treatment of disorders

    Expires Mon Jan 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11426373

    Gamma-hydroxybutyrate compositions and their use for the treatment of disorders

    Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11413264

    Carbamoyl phenylalaninol analogs and uses thereof

    Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11253494

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon Feb 17 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11149000

    Carbamoyl phenylalaninol compounds and uses thereof

    Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10864181

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10710958

    Carbamoyl phenylalaninol compounds and uses thereof

    Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10675258

    Method of using gamma-hydroxybutyrate compositions for the treatment of disorders

    Expires Mon Jun 04 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10213400

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10195168

    Gamma-hydroxybutyrate compositions and their uses for the treatment of disorders

    Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9707270

    Method for administering ω-conopeptide

    Expires Mon Jul 13 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9555017

    Methods of making a mixture of salts of gamma-hydroxybutyrate

    Expires Mon Jan 26 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9486426

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon Nov 03 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9132107

    Gamma-hydroxybutyrate compositions and their use for the treatment of disorders

    Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9050302

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8901173

    Gamma-hydroxybutyrate compositions and their use for the treatment of disorders

    Expires Mon Nov 27 2034 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8772306

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Expires Mon Jul 03 2034 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8765680

    Method for administering omega-conopeptide

    Expires Mon Jun 26 2034 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is calcium oxybate?

calcium oxybate (XYWAV) is a gaba-b receptor agonist. Associated with Jazz Pharmaceuticals Ireland Limited. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for calcium oxybate?

XYWAV is a marketed brand name for calcium oxybate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of calcium oxybate?

calcium oxybate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.