Wednesday, July 8, 2026

Drug profile · INN

butenafine hydrochloride

butenafine hydrochloride (LOTRIMIN ULTRA) is a squalene monooxygenase inhibitor. Route of administration: topical. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — butenafine hydrochloride
US status
approved
Class
Route
TOPICAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

butenafine hydrochloride (LOTRIMIN ULTRA) is a squalene monooxygenase inhibitor. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN butenafine hydrochloride
Brand LOTRIMIN ULTRA
Mechanism Squalene monooxygenase inhibitor
Target Squalene monooxygenase
Route TOPICAL
Formulation CREAM

Mechanism of action

Squalene monooxygenase inhibitor

Primary target: Squalene monooxygenase

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. naftifine hydrochloride Squalene monooxygenase inhibitor
  2. terbinafine Squalene monooxygenase inhibitor
  3. terbinafine hydrochloride Squalene monooxygenase inhibitor

Frequently asked questions

What is butenafine hydrochloride?

butenafine hydrochloride (LOTRIMIN ULTRA) is a squalene monooxygenase inhibitor. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for butenafine hydrochloride?

LOTRIMIN ULTRA is a marketed brand name for butenafine hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of butenafine hydrochloride?

butenafine hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.