Saturday, July 11, 2026

Drug profile · INN

brimonidine

brimonidine (ALPHAGAN) is a adrenergic receptor alpha-2 agonist. Associated with AbbVie.

EMA: approved TGA: approved Dermatologicals (D11) D11AX21
Patents linked 3
Pipeline programs 7
News articles 0
Drug details — brimonidine
Class
Dermatologicals (D11)
Route
Patents
3
Programs
7
Data quality
0.83

Quick answer

brimonidine (ALPHAGAN) is a adrenergic receptor alpha-2 agonist. Associated with AbbVie.

Key facts

INN brimonidine
Brand ALPHAGAN
Mechanism Adrenergic receptor alpha-2 agonist
Therapeutic class Dermatologicals (D11)
ATC code D11AX21
Originator AbbVie

Mechanism of action

Adrenergic receptor alpha-2 agonist

Approval history

Authority Status Date
EMA approved
TGA approved

Pipeline programs

  1. Aceclidine+Brimonidine combination ophthalmic solution Phase 3 · LENZ Therapeutics · Presbyopia
  2. Brimo PS DDS® Phase 2 · Allergan Pharmaceuticals International · Patients Who Participated in an Intravitreal Brimo PS DDS® S
  3. IMGN151-1001 Phase 2 · AbbVie Deutschland GmbH · Recurrent endometrial cancer, recurrent epithelial ovarian,
  4. IMGN853-0424 Phase 2 · AbbVie Deutschland GmbH · Recurrent Ovarian Cancer with High Folate Receptor-Alpha Exp
  5. Aceclidine + Brimonidine Phase 1 · LENZ Therapeutics · Eye Diseases
  6. LNZ101 (Aceclidine /Brimonidine) ophthalmic solution Phase 1 · LENZ Therapeutics · Presbyopia
  7. brinzolamide 1%/brimonidine 0.2% fixed combination Approved · Novartis India · Glaucoma

Related & competitor drugs

  1. beremagene geperpavec Dermatologicals (D03)
  2. dupilumab Dermatologicals (D11)
  3. imiquimod Dermatologicals (D06)
  4. lebrikizumab Dermatologicals (D11)
  5. retapamulin Dermatologicals (D06)
  6. tacrolimus Dermatologicals (D11)
  1. EP 2079529

    ANTIMIKROBIELLE ZUSAMMENSETZUNG MIT EINEM GEHALT AN BISPYRIDINIUMALKAN (OCTENIDIN-DIHYDROCHLORID)

    Expires Tue Jul 17 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. EP 1926473

    ANTIMIKROBIELLE ZUBEREITUNGEN MIT EINEM IN LIPOSOMEN VERKAPSELTEN GEHALT AN OCTENIDINDIHYDROCHLORID

    Expires Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. WO 2007031520

    UTILISATION DE DICHLORHYDRATE D'OCTENIDINE DANS DES PREPARATIONS SEMI-SOLIDES

    Expires Wed Mar 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is brimonidine?

brimonidine (ALPHAGAN) is a adrenergic receptor alpha-2 agonist. Associated with AbbVie.

What is the brand name for brimonidine?

ALPHAGAN is a marketed brand name for brimonidine. Check FDA Drugs@FDA for the current US label holder and prescribing information.