Friday, July 10, 2026

Drug profile · INN

belumosudil

belumosudil (REZUROCK) is a rho-associated protein kinase inhibitor.

EMA: approved Antineoplastic and immunomodulating agents (L04) L04AA48
Patents linked 2
Pipeline programs 3
News articles 0
Drug details — belumosudil
Class
Antineoplastic and immunomodulating agents (L04)
Route
Patents
2
Programs
3
Data quality
0.83

Quick answer

belumosudil (REZUROCK) is a rho-associated protein kinase inhibitor.

Key facts

INN belumosudil
Brand REZUROCK
Mechanism Rho-associated protein kinase inhibitor
Target Rho-associated protein kinase 2
Therapeutic class Antineoplastic and immunomodulating agents (L04)
ATC code L04AA48

Mechanism of action

Rho-associated protein kinase inhibitor

Primary target: Rho-associated protein kinase 2

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. EFC17757 Phase 3 · Sanofi-Aventis U.S · chronic graft versus host disease
  2. ACT16482-05 Phase 2 · Sanofi-Aventis U.S · Cancer
  3. SAR445761 - belumosudil, belumosudil Phase 2 · Sanofi-Aventis U.S · Chronic graft versus host disease.

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Related patents

  1. US 12157729

    Solid state forms of Belumosudil and Belumosudil salts

    Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11773083

    Solid state forms of Belumosudil and Belumosudil salts

    Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is belumosudil?

belumosudil (REZUROCK) is a rho-associated protein kinase inhibitor.

What is the brand name for belumosudil?

REZUROCK is a marketed brand name for belumosudil. Check FDA Drugs@FDA for the current US label holder and prescribing information.