Friday, July 10, 2026

Drug profile · INN

bardoxolone methyl

bardoxolone methyl (IMBARKYD) is a keap1/nrf2 inhibitor.

EMA: application withdrawn
Patents linked 0
Pipeline programs 1
News articles 0
Drug details — bardoxolone methyl
Class
Route
Patents
0
Programs
1
Data quality
0.83

Quick answer

bardoxolone methyl (IMBARKYD) is a keap1/nrf2 inhibitor.

Key facts

INN bardoxolone methyl
Brand IMBARKYD
Mechanism Keap1/Nrf2 inhibitor
Target Inhibitor of nuclear factor kappa-B kinase subunit beta

Mechanism of action

Keap1/Nrf2 inhibitor

Primary target: Inhibitor of nuclear factor kappa-B kinase subunit beta

Approval history

Authority Status Date
EMA application withdrawn

Pipeline programs

  1. Bardoxolone methyl Phase 3 · Biogen · Pulmonary Hypertension

Frequently asked questions

What is bardoxolone methyl?

bardoxolone methyl (IMBARKYD) is a keap1/nrf2 inhibitor.

What is the brand name for bardoxolone methyl?

IMBARKYD is a marketed brand name for bardoxolone methyl. Check FDA Drugs@FDA for the current US label holder and prescribing information.