Wednesday, July 8, 2026

Drug profile · INN

azathioprine

azathioprine (APO-AZATHIOPRINE) is a amidophosphoribosyltransferase inhibitor. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L04) L04AX01
US status approved
Patents linked 0
Pipeline programs 20
News articles 0
Congress events 2
Drug details — azathioprine
US status
approved
Class
Antineoplastic and immunomodulating agents (L04)
Route
ORAL
Patents
0
Programs
20
Data quality
0.89

Quick answer

azathioprine (APO-AZATHIOPRINE) is a amidophosphoribosyltransferase inhibitor. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN azathioprine
Brand APO-AZATHIOPRINE
Mechanism Amidophosphoribosyltransferase inhibitor
Target Amidophosphoribosyltransferase
Therapeutic class Antineoplastic and immunomodulating agents (L04)
Route ORAL
Formulation TABLET
ATC code L04AX01

Mechanism of action

Amidophosphoribosyltransferase inhibitor

Primary target: Amidophosphoribosyltransferase

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved

Congress & event coverage

  • Presentation
    DIA

    1 presentation · regulatory

  • Presentation
    ScopeX

    1 presentation · general

Pipeline programs

  1. APHP200026 Phase 3 · PARItec · Patients with GPA and inadequate response to standard of car
  2. APHP200038 Phase 3 · PARItec · lupus nephritis
  3. APHP211057 Phase 3 · PARItec · myelin oligodendrocytes glycoprotein antibody associated dis
  4. Azathioprine Phase 3 · First People's Hospital · Myasthenia Gravis
  5. C0251010 Phase 3 · First Biotech (Australia) · Idiopathic Inflammatory Myopathy (including dermatomyositis
  6. D20180135 Phase 3 · PARItec · Eosinophilic granulomatosis with polyangiitis (EGPA), former
  7. INTENSIFY MDD Phase 3 · Disc Medicine · Major depressive disorder
  8. KYV101-006 Phase 3 · Kyverna Therapeutics · Generalized myasthenia gravis

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is azathioprine?

azathioprine (APO-AZATHIOPRINE) is a amidophosphoribosyltransferase inhibitor. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for azathioprine?

APO-AZATHIOPRINE is a marketed brand name for azathioprine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of azathioprine?

azathioprine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.