Friday, July 10, 2026

Drug profile · INN

autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t)

autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t) (PROVENGE) is a somatic cell supplemental therapy.

EMA: withdrawn Antineoplastic and immunomodulating agents (L03) L03AX17
Patents linked 0
Pipeline programs 6
News articles 0
Drug details — autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t)
Class
Antineoplastic and immunomodulating agents (L03)
Route
Patents
0
Programs
6
Data quality
0.83

Quick answer

autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t) (PROVENGE) is a somatic cell supplemental therapy.

Key facts

INN autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t)
Brand PROVENGE
Mechanism Somatic cell supplemental therapy
Therapeutic class Antineoplastic and immunomodulating agents (L03)
ATC code L03AX17

Mechanism of action

Somatic cell supplemental therapy

Approval history

Authority Status Date
EMA withdrawn

Pipeline programs

  1. Drotrecogin alfa (activated) Phase 3 · Eli Lilly and · Sepsis
  2. eptacog alfa (activated) Phase 3 · Novo Nordisk A/S · Acquired Bleeding Disorder
  3. Jinling37ICUZCY Phase 2 · Chinese University of · Acute Lower Gastrointestinal Dysfunction
  4. Phage Therapy Phase 2 · Adaptive Biotechnologies · Prosthetic Joint Infection
  5. activated recombinant human factor VII Phase 2 · Novo Nordisk A/S · Acquired Bleeding Disorder
  6. Mononuclear cells Unknown · Shandong Provincial Hospital · Chronic Atrophic Gastritis

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t)?

autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t) (PROVENGE) is a somatic cell supplemental therapy.

What is the brand name for autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t)?

PROVENGE is a marketed brand name for autologous peripheral-blood mononuclear cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor (sipuleucel-t). Check FDA Drugs@FDA for the current US label holder and prescribing information.