Friday, July 10, 2026

Drug profile · INN

asfotase alfa

asfotase alfa (STRENSIQ) is a pyrophosphate hydrolytic enzyme. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved PMDA: approved Alimentary tract and metabolism (A16) A16AB
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — asfotase alfa
US status
approved
Class
Alimentary tract and metabolism (A16)
Route
INJECTION
Patents
0
Programs
2
Data quality
0.84

Quick answer

asfotase alfa (STRENSIQ) is a pyrophosphate hydrolytic enzyme. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN asfotase alfa
Brand STRENSIQ
Mechanism Pyrophosphate hydrolytic enzyme
Target Pyrophosphate
Therapeutic class Alimentary tract and metabolism (A16)
Route INJECTION
Formulation SOLUTION
ATC code A16AB

Mechanism of action

Pyrophosphate hydrolytic enzyme

Primary target: Pyrophosphate

Approval history

Authority Status Date
FDA approved
EMA approved
PMDA approved

Pipeline programs

  1. ALXN1850-HPP-303 Phase 3 · Alexion Europe SAS · Hypophosphatasia
  2. AA-HPP-407 Approved · Alexion Europe SAS · HYPOPHOSPHATASIA

Related & competitor drugs

  1. agalsidase alfa Alimentary tract and metabolism (A16)
  2. alendronate sodium Farnesyl diphosphate synthase inhibitor
  3. alogliptin Alimentary tract and metabolism (A10)
  4. alogliptin benzoate Alimentary tract and metabolism (A10)
  5. aprepitant Alimentary tract and metabolism (A04)
  6. budesonide Alimentary tract and metabolism (A07)

Frequently asked questions

What is asfotase alfa?

asfotase alfa (STRENSIQ) is a pyrophosphate hydrolytic enzyme. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for asfotase alfa?

STRENSIQ is a marketed brand name for asfotase alfa. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of asfotase alfa?

asfotase alfa has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.