Friday, July 10, 2026

Drug profile · INN

arginine

arginine (LYSAKARE) is an FDA-listed pharmaceutical active ingredient.

EMA: approved Various (V03) V03AF11
Patents linked 16
Pipeline programs 12
News articles 0
Drug details — arginine
Class
Various (V03)
Route
Patents
16
Programs
12
Data quality
0.83

Quick answer

arginine (LYSAKARE) is an FDA-listed pharmaceutical active ingredient.

Key facts

INN arginine
Brand LYSAKARE
Therapeutic class Various (V03)
ATC code V03AF11

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. C5041006 Phase 3 · Anaxis Pharma · Crohn's Disease
  2. CAAA601A22301 Phase 3 · Advanced Accelerator Applications · Patients with somatostatin receptor positive, well-different
  3. CAAA601A62301 Phase 3 · Novartis India · Gastroenteropancreatic neuroendocrine tumor (GEP-NET)
  4. Etrasimod Arginine Blue Phase 3 · Anaxis Pharma · Ulcerative Colitis
  5. C5041018 Phase 2 · First Biotech (Australia) · Ulcerative Colitis
  6. CAAA601A32201 Phase 2 · Advanced Accelerator Applications · somatostatin receptor positive gastroenteropancreatic neuroe
  7. CAAA601A42101 Phase 2 · Novartis India · Extensive stage small cell lung cancer (ES-SCLC)
  8. PROICM 2021-04 REL Phase 2 · George Institute for · Neuroendocrine tumor

Related & competitor drugs

  1. besilesomab Various (V09)
  2. deferasirox Various (V03)
  3. ferric citrate coordination complex Various (V03)
  4. folic acid Various (V04)
  5. sevelamer carbonate Various (V03)
  6. sugammadex sodium Various (V03)

Related patents

  1. US 12414953

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Expires Mon Sep 11 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11725008

    Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases

    Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11524962

    Substituted pyrrolo[2,3-d]pyrimidines as inhibitors of protein arginine methyl transferase 5 (PRMT5)

    Expires Mon Dec 08 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11452775

    Detection of arginine methylation of EGFR for prediction of resistance to therapy

    Expires Mon Sep 22 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11254683

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Expires Mon Feb 17 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11220524

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Expires Mon Jan 06 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11214574

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Expires Mon Dec 30 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11208416

    Selective inhibitors of protein arginine methytransterase 5 (PRMT5)

    Expires Mon Dec 23 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11078205

    Selective inhibitors of protein arginine methlytransferase 5 (PRMT5)

    Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11028083

    Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases

    Expires Mon Jun 03 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10711007

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10570140

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Expires Mon Feb 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10537635

    Detection of arginine methylation of EGFR for prediction of resistance to therapy

    Expires Mon Jan 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7923535

    Tryptophan as a functional replacement for ADP-ribose-arginine in recombinant proteins

    Expires Mon Apr 07 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7541139

    Tryptophan as a functional replacement for ADP-ribose-arginine in recombinant proteins

    Expires Mon May 28 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 6476037

    L-arginine and phosphodiesterase (PDE) inhibitor synergism

    Expires Mon Oct 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is arginine?

arginine (LYSAKARE) is an FDA-listed pharmaceutical active ingredient.

What is the brand name for arginine?

LYSAKARE is a marketed brand name for arginine. Check FDA Drugs@FDA for the current US label holder and prescribing information.