Wednesday, July 8, 2026

Drug profile · INN

anagrelide hydrochloride

anagrelide hydrochloride (ANAGRELIDE HYDROCHLORIDE) is a phosphodiesterase 3 inhibitor. Associated with Takeda. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 20
Pipeline programs 5
News articles 0
Drug details — anagrelide hydrochloride
US status
approved
Class
Route
ORAL
Patents
20
Programs
5
Data quality
0.89

Quick answer

anagrelide hydrochloride (ANAGRELIDE HYDROCHLORIDE) is a phosphodiesterase 3 inhibitor. Associated with Takeda. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN anagrelide hydrochloride
Brand ANAGRELIDE HYDROCHLORIDE
Mechanism Phosphodiesterase 3 inhibitor
Target Phosphodiesterase 3
Route ORAL
Formulation CAPSULE
Originator Takeda

Mechanism of action

Phosphodiesterase 3 inhibitor

Primary target: Phosphodiesterase 3

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Anagrelide Hydrochloride Phase 3 · Takeda · Essential Thrombocythemia (ET)
  2. MK-3543-006 Phase 3 · MSD Merck Sharp · Essential Thrombocythemia patients who have an inadequate re
  3. SPD422 (anagrelide hydrochloride) Phase 3 · Takeda · Essential Thrombocythemia (ET)
  4. anagrelide hydrochloride Phase 2 · Takeda · Essential Thrombocythaemia
  5. Anagrelide Approved · Takeda · Thrombocythemia, Hemorrhagic

Related & competitor drugs

  1. cilostazol Phosphodiesterase 3A inhibitor
  2. dyphylline Phosphodiesterase 4 inhibitor
  3. ensifentrine Respiratory system (R03)
  4. inamrinone lactate Phosphodiesterase 3A inhibitor
  5. milrinone lactate Phosphodiesterase 3A inhibitor
  1. US 12421188

    Heterocyclic compound and use thereof

    Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12415782

    Heterocyclic compound and use thereof

    Expires Mon Sep 11 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12409210

    CNS delivery of therapeutic agents

    Expires Mon Sep 04 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12391765

    Methods and materials for assessing response to plasmablast- and plasma cell-depleting therapies

    Expires Mon Aug 14 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12391760

    Method of treating primary sclerosing cholangitis

    Expires Mon Aug 14 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12384770

    Heterocyclic compound

    Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12383587

    AAV triple-plasmid system

    Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12378256

    Heterocyclic compound

    Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12358879

    Heterocyclic compound

    Expires Mon Jul 10 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12337020

    Bacteriophage compositions

    Expires Mon Jun 19 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12319940

    Methods for purification of arylsulfatase A

    Expires Mon May 29 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 12290531

    Compositions targeting BCMA and methods of use thereof

    Expires Mon May 01 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12286456

    Purification of virus like particles

    Expires Mon Apr 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12281073

    Substituted piperidine compound and use thereof

    Expires Mon Apr 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12202797

    Method for producing pyrrole compound

    Expires Mon Jan 16 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12201683

    Methods for preventing dengue and hepatitis a

    Expires Mon Jan 16 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12188948

    Metabolite biomarkers for diseases associated with the contact activation system

    Expires Mon Jan 02 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12171777

    Methods of making a cyclic dinucleotide

    Expires Mon Dec 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12171832

    Methods of treating ulcerative colitis

    Expires Mon Dec 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12168041

    Methods and compositions for CNS delivery of arylsulfatase A

    Expires Mon Dec 12 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is anagrelide hydrochloride?

anagrelide hydrochloride (ANAGRELIDE HYDROCHLORIDE) is a phosphodiesterase 3 inhibitor. Associated with Takeda. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for anagrelide hydrochloride?

ANAGRELIDE HYDROCHLORIDE is a marketed brand name for anagrelide hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of anagrelide hydrochloride?

anagrelide hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.