Wednesday, July 8, 2026

Drug profile · INN

amphotericin b

amphotericin b (FUNGILIN) is a ergosterol sequestering agent. Associated with Lacuna Pharma Pty Ltd. Route of administration: topical. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 8
Pipeline programs 10
News articles 1
Drug details — amphotericin b

Quick answer

amphotericin b (FUNGILIN) is a ergosterol sequestering agent. Associated with Lacuna Pharma Pty Ltd. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN amphotericin b
Brand FUNGILIN
Mechanism Ergosterol sequestering agent
Target Ergosterol
Route TOPICAL
Formulation INJECTABLE, LIPOSOMAL

Mechanism of action

Ergosterol sequestering agent

Primary target: Ergosterol

Approval history

Authority Status Date
FDA approved
TGA approved

Recent coverage

Pipeline programs

  1. FMGX-CS-302 Phase 3 · Anaxis Pharma · Invasive mold infections caused by Aspergillus spp., Fusariu
  2. Liposomal Amphotericin B (LAmB) Phase 3 · Duke University · Talaromycosis
  3. ALL3024 Phase 2 · Telethon Foundation · Very High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL)
  4. APHP221107 Phase 2 · PARItec · Healthy volunteers : Healthy adults with no history of gast
  5. Amphotericin B Phase 2 · Matinas BioPharma Holdings · Candidiasis, Chronic Mucocutaneous
  6. Encochleated Amphotericin B Phase 2 · Matinas BioPharma Holdings · Cryptococcal Infections
  7. Oral Encochleated Amphotericin B (CAMB) Phase 2 · Matinas BioPharma Holdings · Vulvovaginal Candidiases
  8. Oral Encochleated Amphotericin B (CAMB) Phase 2 · Matinas BioPharma Holdings · Vulvovaginitis

Related & competitor drugs

  1. nystatin Ergosterol sequestering agent
  2. natamycin Ergosterol sequestering agent
  1. US 12409227

    Cochleates made with soy phosphatidylserine

    Expires 2045-09-04T00:00:00.000Z

    granted
  2. US 11964019

    Cochleates made with soy phosphatidylserine

    Expires 2044-04-18T00:00:00.000Z

    granted
  3. US 11389407

    Cochleates and methods of using the same to enhance tissue penetration of pharmacologically active agent

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    granted
  4. US 10716860

    Cochleates made with soy phosphatidylserine

    Expires 2040-07-16T00:00:00.000Z

    granted
  5. US 10058521

    Omega-3 pentaenoic acid compositions and methods of use

    Expires 2038-08-23T00:00:00.000Z

    granted
  6. US 9775907

    Cochleates made with soy phosphatidylserine

    Expires 2037-09-28T00:00:00.000Z

    granted
  7. US 8906964

    Methods of administering compositions comprising docosapentaenoic acid

    Expires 2034-12-04T00:00:00.000Z

    granted
  8. US 7326691

    Compositions comprising amphotericin B, methods, and systems

    Expires 2028-01-31T00:00:00.000Z

    granted

Frequently asked questions

What is amphotericin b?

amphotericin b (FUNGILIN) is a ergosterol sequestering agent. Associated with Lacuna Pharma Pty Ltd. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for amphotericin b?

FUNGILIN is a marketed brand name for amphotericin b. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of amphotericin b?

amphotericin b has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.