Wednesday, July 8, 2026

Drug profile · INN

amitriptyline hydrochloride

amitriptyline hydrochloride (AMITRIL) is a norepinephrine transporter inhibitor. Associated with Teva Pharma GmbH. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 9
Pipeline programs 2
News articles 0
Drug details — amitriptyline hydrochloride
US status
approved
Class
Route
INJECTION
Patents
9
Programs
2
Data quality
0.89

Quick answer

amitriptyline hydrochloride (AMITRIL) is a norepinephrine transporter inhibitor. Associated with Teva Pharma GmbH. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN amitriptyline hydrochloride
Brand AMITRIL
Mechanism Norepinephrine transporter inhibitor
Target Sodium-dependent noradrenaline transporter
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Norepinephrine transporter inhibitor

Primary target: Sodium-dependent noradrenaline transporter

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Epo Phase 2 · Chinese Academy of · Premature Infant
  2. Amitriptyline Hydrochloride 25Mg Tablet(Hunan Dongting) Phase 1 · First People's Hospital · Depressive Disorder

Related & competitor drugs

  1. atomoxetine hydrochloride Norepinephrine transporter inhibitor
  2. desipramine hydrochloride Norepinephrine transporter inhibitor
  3. desvenlafaxine fumarate Norepinephrine transporter inhibitor
  4. doxepin hydrochloride Norepinephrine transporter inhibitor
  5. duloxetine hydrochloride Norepinephrine transporter inhibitor
  6. imipramine hydrochloride Serotonin transporter inhibitor
  1. US 11839594

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Dec 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11737991

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10864176

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10864175

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10736859

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Aug 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10322094

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Jun 13 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10117936

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Nov 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9956188

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Apr 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9636408

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    Expires Mon Apr 27 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is amitriptyline hydrochloride?

amitriptyline hydrochloride (AMITRIL) is a norepinephrine transporter inhibitor. Associated with Teva Pharma GmbH. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for amitriptyline hydrochloride?

AMITRIL is a marketed brand name for amitriptyline hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of amitriptyline hydrochloride?

amitriptyline hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.