Wednesday, July 8, 2026

Drug profile · INN

amifampridine

amifampridine (RUZURGI) is a voltage-gated potassium channel blocker. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved Nervous system (N07) N07XX05
US status approved
Patents linked 0
Pipeline programs 7
News articles 0
Drug details — amifampridine
US status
approved
Class
Nervous system (N07)
Route
ORAL
Patents
0
Programs
7
Data quality
0.84

Quick answer

amifampridine (RUZURGI) is a voltage-gated potassium channel blocker. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN amifampridine
Brand RUZURGI
Mechanism Voltage-gated potassium channel blocker
Target Voltage-gated potassium channel
Therapeutic class Nervous system (N07)
Route ORAL
Formulation TABLET
ATC code N07XX05

Mechanism of action

Voltage-gated potassium channel blocker

Primary target: Voltage-gated potassium channel

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved

Pipeline programs

  1. Amifampridine Phosphate Phase 3 · CATALYST PHARMACEUTICALS · Myasthenia Gravis, MuSK
  2. Amifampridine Phosphate Phase 3 · CATALYST PHARMACEUTICALS · Lambert Eaton Myasthenic Syndrome
  3. Amifampridine Phosphate Phase 3 · CATALYST PHARMACEUTICALS · Myasthenia Gravis, Generalized
  4. MyelomaXIV Phase 3 · Takeda · Multiple Myeloma
  5. amifampridine phosphate Phase 3 · CATALYST PHARMACEUTICALS · Myasthenic Syndromes, Congenital
  6. Amifampridine Phosphate Phase 2 · CATALYST PHARMACEUTICALS · Muscular Atrophy, Spinal
  7. Amifampridine Phosphate 10 MG Oral Tablet Phase 2 · CATALYST PHARMACEUTICALS · Spinal Muscular Atrophy Type 3

Related & competitor drugs

  1. amifampridine phosphate Voltage-gated potassium channel blocker
  2. aripiprazole Nervous system (N05)
  3. brexpiprazole Nervous system (N05)
  4. brivaracetam Nervous system (N03)
  5. bupivacaine Nervous system (N01)
  6. buprenorphine Nervous system (N07)

Frequently asked questions

What is amifampridine?

amifampridine (RUZURGI) is a voltage-gated potassium channel blocker. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for amifampridine?

RUZURGI is a marketed brand name for amifampridine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of amifampridine?

amifampridine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.