Wednesday, July 8, 2026

Drug profile · INN

alprostadil

alprostadil (CAVERJECT IMPULSE) is a prostanoid ep1 receptor agonist. Associated with Pfizer Australia Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 11
Pipeline programs 7
News articles 0
Drug details — alprostadil
US status
approved
Class
Route
INJECTION
Patents
11
Programs
7
Data quality
0.84

Quick answer

alprostadil (CAVERJECT IMPULSE) is a prostanoid ep1 receptor agonist. Associated with Pfizer Australia Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN alprostadil
Brand CAVERJECT IMPULSE
Mechanism Prostanoid EP1 receptor agonist
Target Prostaglandin E2 receptor EP1 subtype
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Prostanoid EP1 receptor agonist

Primary target: Prostaglandin E2 receptor EP1 subtype

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. 060018-PG-PSC-217 Phase 3 · Anaxis Pharma · Allergic rhinoconjunctivitis with or without asthma due to c
  2. CLI-05993AA5-06 Phase 3 · Chiesi Farmaceutici S.p.A · Uncontrolled Asthma
  3. ACE-LY-106 Phase 1 · Anaxis Pharma · Mantle Cell Lymphoma
  4. Elimusertib (BAY1895344) Phase 1 · Bayer HealthCare Animal · Advanced Solid Tumor
  5. Alprostadil Approved · First People's Hospital · Stroke
  6. Pulse Sequence Approved · Aspire Biopharma Holdings · Atrial Fibrillation
  7. Virtual Reality (VR) Contrast Function Test Unknown · Genzyme Europe · Age-Related Macular Degeneration
  1. CN 115003329

    Parapoxvirus for conditioning and treating coronavirus infections

    Expires Thu Aug 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. BR 112021015776

    Edição de gene para hemofilia a com expressão de fator viii melhorada

    Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. DE 102019218587

    Kontrastmittelbasierte Gefäßdarstellung

    Expires Tue May 28 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 2020384125

    GENE EDITING FOR HEMOPHILIA A WITH IMPROVED FACTOR VIII EXPRESSION

    Expires Wed Dec 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. EP 3728594

    MATERIALIEN UND VERFAHREN ZUR BEHANDLUNG DES USHER-SYNDROMS TYP 2A

    Expires Tue Oct 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. CA 3121191

    CAS9 DE CODAGE D'ARNM OPTIMISE DESTINE A ETRE UTILISE DANS DES LNP

    Expires Wed May 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. CA 3118090

    COMPOSITIONS ET PROCEDES POUR EDITION DU GENOME A MEDIATION PAR NHEJ

    Expires Wed May 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. CA 3097885

    PROCEDES ET COMPOSITIONS D'EPUISEMENT DE LYMPHOCYTES T CYTOTOXIQUES

    Expires Wed Oct 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. CA 3079172

    COMPOSITIONS ET METHODES POUR L'EDITION GENIQUE POUR L'HEMOPHILIE A

    Expires Wed Apr 20 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. WO 2018227427

    DÉRIVÉS DE DIAZÉPANE PONTÉS SUBSTITUÉS ET LEUR UTILISATION

    Expires Wed Dec 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. WO 2018128828

    NOUVEAUX MIMÉTIQUES D'HEPCIDINE ET LEURS UTILISATIONS

    Expires Wed Jul 07 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is alprostadil?

alprostadil (CAVERJECT IMPULSE) is a prostanoid ep1 receptor agonist. Associated with Pfizer Australia Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for alprostadil?

CAVERJECT IMPULSE is a marketed brand name for alprostadil. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of alprostadil?

alprostadil has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.