Thursday, July 9, 2026

pharma · Renal Impairment · Urinary Tract Infection · SPRO

Spero Therapeutics

Spero Therapeutics is a pharma organization headquartered in Cambridge, USA. It trades on NYSE under ticker SPRO. Primary therapeutic focus areas include Renal Impairment, Urinary Tract Infection, complicated urinary tra

675 Massachusetts Ave, 14th Floor, Cambridge, MA 02139, US HQ
2013 Founded
45 Employees
Public company Type
SPRO · NYSE Ticker
Company details
Status
Public
HQ
675 Massachusetts Ave, 14th Floor, Cambridge, MA 02139, US
Founded
2013
Employees
45
Programs
21
Drugs
9
Patents
16

Quick answer

Spero Therapeutics is a pharma organization headquartered in Cambridge, USA. It trades on NYSE under ticker SPRO. Primary therapeutic focus areas include Renal Impairment, Urinary Tract Infection, complicated urinary tract infection (cUTI) or acute pyelonephritis (AP), Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD), Mycobacterium Avium Complex. NovaPharmaNews links 21 clinical program(s), 0 drug profile(s), and 16 patent record(s) to this entity from public FDA, EMA, ClinicalTrials.gov, and USPTO sources. Pipeline phase mix: phase 1 (16), phase 3 (3), phase 2 (2).

Company snapshot

We are a clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare diseases and diseases with high unmet need.

  • 21 active pipeline program(s) linked via ClinicalTrials.gov.
  • 16 US patent(s) indexed to this assignee profile.
  • 21 trial update(s) in the last 12 months.

Public regulatory, clinical, patent, and corporate records for Spero Therapeutics. Not investment advice.

Lead pipeline drugs

Active clinical programs

  • SPR994-305 complicated urinary tract infection (cUTI) or acute pyelonephritis (AP)
    Phase 3
  • TBP-PI-HBr Urinary Tract Infection
    Phase 3
  • TBPM-PI-HBr Complicated Urinary Tract Infection
    Phase 3
  • Placebo Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)
    Phase 2

Momentum

Proprietary activity score for Spero Therapeutics.

1 active signal

20 /100 +0 vs 30 days ago

Signal breakdown

  • Clinical trials 23 30d
  • Nova articles 0 30d
  • Patents filed 0 30d
  • FDA actions 0 30d
  • SEC filings 0 30d
  • Conference presentations 0 90d
  • Pipeline advances 0 30d

Recent activity

Latest pipeline, patent, and corporate events for Spero Therapeutics.

  1. Clinical update

    SPR994-305 — Phase 3

  2. Clinical update

    Tebipenem tablet form — Phase 1

  3. Clinical update

    Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) — Phase 1

  4. Clinical update

    Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) - Reference — Phase 1

  5. Clinical update

    Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) + Placebo — Phase 1

View all clinical trial activity →

Quick answers

Common questions about this sponsor — for analysts and search.

  • What is Spero Therapeutics?

    Spero Therapeutics is a pharma organization headquartered in Cambridge, USA. It trades on NYSE under ticker SPRO. Primary therapeutic focus areas include Renal Impairment, Urinary Tract Infection, complicated urinary tract infection (cUTI) or acute pyelonephritis (AP), Nontubercu

  • Is Spero Therapeutics publicly traded?

    Yes. Spero Therapeutics is listed with ticker SPRO on NYSE per SEC EDGAR records linked on this profile.

  • What drugs does Spero Therapeutics develop or market?

    We link 9 drug profile(s) where Spero Therapeutics is an originator or marketer in FDA or regional approval metadata. See the drug portfolio table on https://novapharmanews.com/companies/spero-therapeutics#company-drugs.

  • What are the latest developments for Spero Therapeutics?

    In the last 12 months our linked public records show 21 trial program update(s) and 1 US patent grant(s) tied to this profile.

  • What therapeutic areas does Spero Therapeutics focus on?

    Spero Therapeutics focuses on Renal Impairment, Urinary Tract Infection, complicated urinary tract infection (cUTI) or acute pyelonephritis (AP) based on our analysis of their pipeline programs and drug development activities.

Therapeutic focus

Therapeutic area distribution

Pipeline concentration by therapeutic area from linked clinical programs.

Programs by therapeutic area

Others
20
Infectious Disease
11