🇺🇸 FDA
Company

Silence

Silence Therapeutics plc

SLN pharma USA

Quick answer

Silence is a pharma company (SLN) headquartered in LONDON, USA with 8 tracked pipeline programs.

Pipeline (8)

project

Atu027 & gemcitabine in lead in safety period

Carcinoma, Pancreatic Ductal

Phase 2 · small_molecule · completed

1 trials project

SLN124

Polycythemia Vera

Phase 2 · small_molecule · active

1 trials project

SLN360

Cardiovascular Diseases

Phase 2 · small_molecule · completed

1 trials project

Atu027

Advanced Solid Tumors

Phase 1 · small_molecule · completed

1 trials project

SLN124

Non-transfusion-dependent Thalassemia

Phase 1 · small_molecule · completed

1 trials project

SLN124

Healthy Volunteers

Phase 1 · small_molecule · completed

1 trials project

SLN124 is a GalNAc conjugated double stranded fully modified siRNA. Sodium chloride 0.9% w/v is used as Placebo

Non-transfusion-dependent Thalassemia

Phase 1 · small_molecule · terminated

1 trials project

SLN360

Hyperlipidemias

Phase 1 · small_molecule · completed

1 trials

Patents (3)

patent

US 12338438

Conjugated oligonucleotide compounds, methods of making and uses thereof

Expires Mon Jun 19 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 10961238

Modulators of hedgehog (Hh) signaling pathway

Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 8614179

Antibacterial combination therapy for the treatment of gram positive bacterial i

Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)