Friday, July 10, 2026

pharma · Metachromatic Leukodystrophy (MLD) · Late Metachromatic Leukodystrophy (MLD)

Shire

Shire drug portfolio — 8 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

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Intelligence · Drug Pipeline

Shire pipeline

Portfolio lens on 8 drugs and development assets — regulatory status, targets, and deep links to NovaPharmaNews drug profiles.

Shire drug portfolio — 8 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Drug portfolio

8 compounds
  1. abacavir

    Antiinfectives for systemic use (J05)

    US regulatory status: approved.

  2. idursulfase

    Alimentary tract and metabolism (A16)

    US regulatory status: approved. Molecular target: Heparan sulfate.

    Target
    Heparan sulfate
    Mechanism
    Heparan sulfate hydrolytic enzyme
  3. Development asset linked to Shire in public FDA and regional records.

  4. Development asset linked to Shire in public FDA and regional records.

  5. maribavir

    Antiinfectives for systemic use (J05)

    US regulatory status: approved. Molecular target: Serine/threonine protein kinase UL97.

    Target
    Serine/threonine protein kinase UL97
    Mechanism
    Phosphotransferase pUL97 inhibitor
  6. Development asset linked to Shire in public FDA and regional records.

  7. Development asset linked to Shire in public FDA and regional records.

  8. velaglucerase alfa

    Alimentary tract and metabolism (A16)

    US regulatory status: approved. Molecular target: Glucocerebroside.

    Target
    Glucocerebroside
    Mechanism
    Glucocerebroside hydrolytic enzyme