Friday, July 10, 2026

pharma · Cystic Fibrosis · Rheumatoid Arthritis · LKFT

Lakefront Biotherapeutics NV

Lakefront Biotherapeutics NV drug portfolio — 26 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Yalelaan 60, 5th floor, Utrecht 3584 CM, NL HQ
2016 Founded
9 Employees
Public company Type
LKFT · NYSE Ticker
Company details
Status
Public
HQ
Yalelaan 60, 5th floor, Utrecht 3584 CM, NL
Founded
2016
Employees
9
Programs
99
Drugs
26
Patents
0
Intelligence · Drug Pipeline

Lakefront Biotherapeutics NV pipeline

Portfolio lens on 26 drugs and development assets — regulatory status, targets, and deep links to NovaPharmaNews drug profiles.

Lakefront Biotherapeutics NV drug portfolio — 26 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Drug portfolio

26 compounds
  1. US regulatory status: approved. Molecular target: Fatty-acid amide hydrolase 1.

    Target
    Fatty-acid amide hydrolase 1
    Mechanism
    Cyclooxygenase inhibitor
  2. ambrisentan

    Cardiovascular system (C02)

    US regulatory status: approved. Molecular target: Endothelin receptor, ET-A/ET-B.

    Target
    Endothelin receptor, ET-A/ET-B
    Mechanism
    Endothelin receptor, ET-A/ET-B antagonist
  3. US regulatory status: approved. Molecular target: Dopamine receptors; D2 & D3.

    Target
    Dopamine receptors; D2 & D3
    Mechanism
    Serotonin (5-HT) receptor antagonist
  4. US regulatory status: approved. Molecular target: Voltage-gated L-type calcium channel.

    Target
    Voltage-gated L-type calcium channel
    Mechanism
    Voltage-gated L-type calcium channel blocker
  5. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records. Mechanism: HMG-CoA reductase inhibitor.

    Mechanism
    HMG-CoA reductase inhibitor
  6. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  7. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  8. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  9. US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  10. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  11. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  12. filgotinib

    Antineoplastic and immunomodulating agents (L04)

    Antineoplastic and immunomodulating agents (L04) compound in Lakefront Biotherapeutics NV's portfolio. Molecular target: Tyrosine-protein kinase JAK1.

    Target
    Tyrosine-protein kinase JAK1
    Mechanism
    Tyrosine-protein kinase JAK3 inhibitor
  13. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  14. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  15. pirfenidone

    Antineoplastic and immunomodulating agents (L04)

    US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  16. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  17. US regulatory status: approved. Molecular target: Glucocorticoid receptor.

    Target
    Glucocorticoid receptor
    Mechanism
    Glucocorticoid receptor agonist
  18. US regulatory status: approved. Molecular target: Glucocorticoid receptor.

    Target
    Glucocorticoid receptor
    Mechanism
    Glucocorticoid receptor agonist
  19. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  20. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  21. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  22. US regulatory status: approved. Molecular target: Polyunsaturated fatty acid 5-lipoxygenase.

    Target
    Polyunsaturated fatty acid 5-lipoxygenase
    Mechanism
    Arachidonate 5-lipoxygenase inhibitor
  23. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  24. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  25. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.

  26. Development asset linked to Lakefront Biotherapeutics NV in public FDA and regional records.