Wednesday, July 8, 2026

pharma · Myelofibrosis · Acute Myeloid Leukemia

Karyopharm Therapeutics

Karyopharm Therapeutics clinical programs — 82 development programs from ClinicalTrials.gov with phase, modality, indication, and trial identifiers.

85 Wells Avenue, Newton, MA 02459, US HQ
313 Employees
NMPA registrant Type
Company details
Status
Public
HQ
85 Wells Avenue, Newton, MA 02459, US
Employees
313
Programs
82
Drugs
53
Patents
38
Intelligence · Clinical Programs

Karyopharm Therapeutics projects

82 ClinicalTrials.gov programs sponsored by Karyopharm Therapeutics.

Karyopharm Therapeutics has 82 clinical development programs indexed from ClinicalTrials.gov, including phase, modality, indication text, and linked NCT identifiers.

Clinical programs

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  1. SELINEXOR for endometrial cancer

    Karyopharm Therapeutics Inc

    endometrial cancer

    phase 3 small molecule active

    1 trial
  2. Selinexor

    Karyopharm Therapeutics Inc

    Dedifferentiated Liposarcoma

    phase 3 small molecule completed

    1 trial
  3. Selinexor

    Karyopharm Therapeutics Inc

    Endometrial Cancer

    phase 3 small molecule active

    2 trials
  4. Selinexor

    Karyopharm Therapeutics Inc

    Multiple Myeloma

    phase 3 small molecule active

    12 trials
  5. Selinexor (combination therapy)

    Karyopharm Therapeutics Inc

    Relapsed/Refractory Diffuse Large B-cell Lymphoma

    phase 3 small molecule active

    1 trial
  6. XPORT-DLBCL-30

    Karyopharm Therapeutics Inc

    Relapsed/Refractory Diffuse Large B-Cell Lymphoma (RR DLBCL)

    phase 3 small molecule active

    1 trial
  7. XPORT-MF-034

    Karyopharm Therapeutics Inc

    Treatment naïve patients with MF

    phase 3 small molecule active

    1 trial
  8. Cyclophosphamide

    Karyopharm Therapeutics Inc

    Myeloma Multiple

    phase 2 small molecule terminated

    1 trial
  9. Decitabine

    Karyopharm Therapeutics Inc

    Ovarian Cancer

    phase 2 small molecule active

    1 trial
  10. Docetaxel

    Karyopharm Therapeutics Inc

    Recurrent Squamous Cell Lung Carcinoma

    phase 2 small molecule terminated

    1 trial
  11. IST-342

    Karyopharm Therapeutics Inc

    Relapsed Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  12. Ibrutinib

    Karyopharm Therapeutics Inc

    Lymphoma

    phase 2 small molecule active

    1 trial
  13. KCP-330-009

    Karyopharm Therapeutics Inc

    Relapsed/Refractory DLBCL, Relapsed/Refractory DLBCL, Relapsed/Refractory DLBCL

    phase 2 other active

    1 trial
  14. KPT-8602

    Karyopharm Therapeutics Inc

    Relapsed/Refractory Multiple Myeloma (RRMM)

    phase 2 small molecule completed

    1 trial
  15. MyDRUG (MMRC-085)

    Karyopharm Therapeutics Inc

    Relapsed Refractory Multiple Myeloma

    phase 2 small molecule completed

    1 trial
  16. Open Label Selinexor

    Karyopharm Therapeutics Inc

    Thymoma

    phase 2 small molecule terminated

    1 trial
  17. Pacritinib

    Karyopharm Therapeutics Inc

    Myelofibrosis

    phase 2 small molecule active

    1 trial
  18. Pembrolizumab

    Karyopharm Therapeutics Inc

    Advanced Urothelial Carcinoma

    phase 2 mab terminated

    1 trial
  19. SELINEXOR

    Karyopharm Therapeutics Inc

    Myelofibrosis

    phase 2 small molecule active

    1 trial
  20. Selinexor

    Karyopharm Therapeutics Inc

    Myelodysplastic Syndrome

    phase 2 small molecule terminated

    1 trial
  21. Selinexor

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia

    phase 2 small molecule completed

    1 trial
  22. Selinexor

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia (AML)

    phase 2 small molecule completed

    3 trials
  23. Selinexor

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia (Relapsed/Refractory)

    phase 2 small molecule completed

    1 trial
  24. Selinexor

    Karyopharm Therapeutics Inc

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  25. Selinexor

    Karyopharm Therapeutics Inc

    Carcinoma, Neuroendocrine

    phase 2 small molecule completed

    1 trial
  26. Selinexor

    Karyopharm Therapeutics Inc

    Coronavirus Infection

    phase 2 small molecule completed

    2 trials
  27. Selinexor

    Karyopharm Therapeutics Inc

    Diabetic Foot Ulcers

    phase 2 small molecule terminated

    1 trial
  28. Selinexor

    Karyopharm Therapeutics Inc

    Diffuse Large B-cell Lymphoma

    phase 2 small molecule active

    1 trial
  29. Selinexor

    Karyopharm Therapeutics Inc

    Glioblastoma

    phase 2 small molecule terminated

    1 trial
  30. Selinexor

    Karyopharm Therapeutics Inc

    Glioblastoma Multiforme

    phase 2 small molecule terminated

    1 trial
  31. Selinexor

    Karyopharm Therapeutics Inc

    Leukemia

    phase 2 small molecule completed

    2 trials
  32. Selinexor

    Karyopharm Therapeutics Inc

    Locally Advanced Unresectable or Metastatic Melanoma

    phase 2 small molecule terminated

    1 trial
  33. Selinexor

    Karyopharm Therapeutics Inc

    Metastatic Colorectal Cancer

    phase 2 small molecule terminated

    1 trial
  34. Selinexor

    Karyopharm Therapeutics Inc

    Multiple Myeloma in Relapse

    phase 2 small molecule active

    1 trial
  35. Selinexor

    Karyopharm Therapeutics Inc

    Multiple Myeloma, Refractory

    phase 2 small molecule active

    1 trial
  36. Selinexor

    Karyopharm Therapeutics Inc

    Myelofibrosis

    phase 2 small molecule active

    2 trials
  37. Selinexor

    Karyopharm Therapeutics Inc

    Myeloma Multiple

    phase 2 small molecule terminated

    1 trial
  38. Selinexor

    Karyopharm Therapeutics Inc

    Non-small Cell Lung Cancer

    phase 2 small molecule terminated

    1 trial
  39. Selinexor

    Karyopharm Therapeutics Inc

    Ovarian Carcinoma

    phase 2 small molecule completed

    1 trial
  40. Selinexor

    Karyopharm Therapeutics Inc

    Peripheral T-cell Lymphoma (PTCL)

    phase 2 small molecule terminated

    1 trial
  41. Selinexor

    Karyopharm Therapeutics Inc

    Primary Myelofibrosis

    phase 2 small molecule terminated

    1 trial
  42. Selinexor

    Karyopharm Therapeutics Inc

    Prostate Cancer

    phase 2 small molecule terminated

    1 trial
  43. Selinexor

    Karyopharm Therapeutics Inc

    Recurrent Small Cell Lung Carcinoma

    phase 2 small molecule terminated

    1 trial
  44. Selinexor

    Karyopharm Therapeutics Inc

    Relapse Multiple Myeloma

    phase 2 small molecule active

    1 trial
  45. Selinexor

    Karyopharm Therapeutics Inc

    Relapsed and Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial
  46. Selinexor

    Karyopharm Therapeutics Inc

    Relapsed or Refractory Diffuse Large B-Cell Lymphoma

    phase 2 small molecule terminated

    1 trial
  47. Selinexor

    Karyopharm Therapeutics Inc

    Smoldering Multiple Myeloma

    phase 2 small molecule active

    1 trial
  48. Selinexor

    Karyopharm Therapeutics Inc

    Solid Tumor Malignancy

    phase 2 small molecule terminated

    1 trial

Frequently asked questions

How many clinical projects does Karyopharm Therapeutics have?

82 published programs are linked to this sponsor in our ClinicalTrials.gov index.

Is this the complete company pipeline?

This directory lists published programs for the sponsor in our database. Partnered or out-licensed assets may appear under multiple companies.