Thursday, July 9, 2026

biotech · Parkinson Disease · Amyotrophic Lateral Sclerosis · DNLI

Denali Therapeutics

Denali Therapeutics is a biotech organization headquartered in South San Francisco, USA. It trades on NYSE under ticker DNLI. Primary therapeutic focus areas include Parkinson Disease, Amyotrophic Lateral Sclerosis, Fron

161 Oyster Point Blvd, South San Francisco, California 94080, US HQ
2015 Founded
567 Employees
Public company Type
DNLI · NYSE Ticker
Company details
Status
Public
HQ
161 Oyster Point Blvd, South San Francisco, California 94080, US
Founded
2015
Employees
567
Programs
23
Drugs
10
Patents
42

Quick answer

Denali Therapeutics is a biotech organization headquartered in South San Francisco, USA. It trades on NYSE under ticker DNLI. Primary therapeutic focus areas include Parkinson Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia (FTD), Mucopolysaccharidosis Type II [MPS II], Hunter Syndrome (Mucopolysaccharidosis Type II [MPS II]). NovaPharmaNews links 23 clinical program(s), 1 drug profile(s), and 42 patent record(s) to this entity from public FDA, EMA, ClinicalTrials.gov, and USPTO sources. Pipeline phase mix: phase 1 (13), phase 2 (6), phase 3 (4).

Company snapshot

Denali Therapeutics is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier using our proprietary TransportVehicle™ platform. We discover, develop and deliver medicines for people living with neurodegenerative, lysosomal storage and other serious diseases.

  • 1 approved product(s) across US/EU regulatory metadata.
  • 23 active pipeline program(s) linked via ClinicalTrials.gov.
  • 42 US patent(s) indexed to this assignee profile.

Public regulatory, clinical, patent, and corporate records for Denali Therapeutics. Not investment advice.

Recent coverage

Lead pipeline drugs

Active clinical programs

Momentum

Proprietary activity score for Denali Therapeutics.

2 active signals

28 /100 +0 vs 30 days ago

Signal breakdown

  • Clinical trials 23 30d
  • Nova articles 2 30d
  • Patents filed 0 30d
  • FDA actions 0 30d
  • SEC filings 0 30d
  • Conference presentations 0 90d
  • Pipeline advances 0 30d

Competitor landscape

Therapeutic-area overlap peers from registry and pipeline signals.

Recent activity

Latest pipeline, patent, and corporate events for Denali Therapeutics.

  1. Clinical update

    DNLI-H-0001 — Phase 2

  2. Clinical update

    DNLI-K-0001 — Phase 1

  3. Clinical update

    DNLI-E-0002 — Phase 2

  4. Clinical update

    Elaprase 2 mg/ml concentrate for solution for infusion — Phase 3

  5. Clinical update

    [14C] BIIB122 ([14C] DNL151) — Phase 1

View all clinical trial activity →

Quick answers

Common questions about this sponsor — for analysts and search.

  • What is Denali Therapeutics?

    Denali Therapeutics is a biotech organization headquartered in South San Francisco, USA. It trades on NYSE under ticker DNLI. Primary therapeutic focus areas include Parkinson Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia (FTD), Mucopolysaccharidosis Type II [MP

  • Is Denali Therapeutics publicly traded?

    Yes. Denali Therapeutics is listed with ticker DNLI on NYSE per SEC EDGAR records linked on this profile.

  • What drugs does Denali Therapeutics develop or market?

    We link 10 drug profile(s) where Denali Therapeutics is an originator or marketer in FDA or regional approval metadata. See the drug portfolio table on https://novapharmanews.com/companies/denali-therapeutics#company-drugs.

  • What are the latest developments for Denali Therapeutics?

    In the last 12 months our linked public records show 23 trial program update(s) and 3 US patent grant(s) tied to this profile.

  • What therapeutic areas does Denali Therapeutics focus on?

    Denali Therapeutics focuses on Parkinson Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia (FTD) based on our analysis of their pipeline programs and drug development activities.

Therapeutic focus

Therapeutic area distribution

Pipeline concentration by therapeutic area from linked clinical programs.

Programs by therapeutic area

Others
24
Neurology
12