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BRIGHT MINDS BIOSCIENCES

BRIGHT MINDS BIOSCIENCES drug portfolio — 200 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

19 Vestry St, New York, NY 10013, US HQ
12 Employees
Public company Type
DRUG · NYSE Ticker
Company details
Status
Public
HQ
19 Vestry St, New York, NY 10013, US
Employees
12
Programs
1063
Drugs
444
Patents
57
Intelligence · Drug Pipeline

BRIGHT MINDS BIOSCIENCES pipeline

Portfolio lens on 200 drugs and development assets — regulatory status, targets, and deep links to NovaPharmaNews drug profiles.

BRIGHT MINDS BIOSCIENCES drug portfolio — 200 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Drug portfolio

200 compounds
  1. abacavir

    Antiinfectives for systemic use (J05)

    US regulatory status: approved.

  2. US regulatory status: approved. Molecular target: Integrin alpha-IIb/beta-3.

    Target
    Integrin alpha-IIb/beta-3
    Mechanism
    Integrin alpha-V/beta-3 inhibitor
  3. US regulatory status: approved. Molecular target: Fatty-acid amide hydrolase 1.

    Target
    Fatty-acid amide hydrolase 1
    Mechanism
    Cyclooxygenase inhibitor
  4. US regulatory status: approved. Mechanism: Glutathione precursor.

    Mechanism
    Glutathione precursor
  5. US regulatory status: approved. Molecular target: DNA polymerase catalytic subunit.

    Target
    DNA polymerase catalytic subunit
    Mechanism
    Human herpesvirus 1 DNA polymerase inhibitor
  6. US regulatory status: approved. Molecular target: DNA polymerase catalytic subunit.

    Target
    DNA polymerase catalytic subunit
    Mechanism
    Human herpesvirus 1 DNA polymerase inhibitor
  7. adalimumab

    Antineoplastic and immunomodulating agents (L04)

    US regulatory status: approved. Molecular target: Tumor necrosis factor.

    Target
    Tumor necrosis factor
    Mechanism
    TNF-alpha inhibitor
  8. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  9. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  10. US regulatory status: approved. Molecular target: Glucocorticoid receptor.

    Target
    Glucocorticoid receptor
    Mechanism
    Glucocorticoid receptor agonist
  11. US regulatory status: approved.

  12. US regulatory status: approved. Molecular target: Interleukin-2 receptor.

    Target
    Interleukin-2 receptor
    Mechanism
    Interleukin-2 receptor agonist
  13. alogliptin

    Alimentary tract and metabolism (A10)

    US regulatory status: approved. Mechanism: Dipeptidyl peptidase IV inhibitor.

    Mechanism
    Dipeptidyl peptidase IV inhibitor
  14. US regulatory status: approved. Molecular target: GABA-A receptor; anion channel.

    Target
    GABA-A receptor; anion channel
    Mechanism
    GABA-A receptor; anion channel positive allosteric modulator
  15. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  16. US regulatory status: approved. Mechanism: Glutamate [NMDA] receptor antagonist.

    Mechanism
    Glutamate [NMDA] receptor antagonist
  17. US regulatory status: approved. Molecular target: Dopamine receptors; D2 & D3.

    Target
    Dopamine receptors; D2 & D3
    Mechanism
    Serotonin (5-HT) receptor antagonist
  18. amlodipine

    Cardiovascular system (C09)

    Cardiovascular system (C09) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Voltage-gated L-type calcium channel blocker.

    Mechanism
    Voltage-gated L-type calcium channel blocker
  19. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  20. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Norepinephrine transporter releasing agent
  21. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Norepinephrine transporter releasing agent
  22. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Norepinephrine transporter releasing agent
  23. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  24. anamorelin

    Various (V03)

    Various (V03) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Ghrelin receptor agonist.

    Mechanism
    Ghrelin receptor agonist
  25. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  26. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  27. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  28. apomorphine

    Genito-urinary system and sex hormones (G04)

    Genito-urinary system and sex hormones (G04) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: D2-like dopamine receptor agonist.

    Mechanism
    D2-like dopamine receptor agonist
  29. US regulatory status: approved. Molecular target: D2-like dopamine receptor.

    Target
    D2-like dopamine receptor
    Mechanism
    D2-like dopamine receptor agonist
  30. aprepitant

    Alimentary tract and metabolism (A04)

    US regulatory status: approved. Molecular target: Substance-P receptor.

    Target
    Substance-P receptor
    Mechanism
    Neurokinin 1 receptor antagonist
  31. aripiprazole

    Nervous system (N05)

    US regulatory status: approved. Molecular target: D(2) dopamine receptor.

    Target
    D(2) dopamine receptor
    Mechanism
    Serotonin 2a (5-HT2a) receptor antagonist
  32. asenapine

    Nervous system (N05)

    US regulatory status: approved. Mechanism: Serotonin 2a (5-HT2a) receptor antagonist.

    Mechanism
    Serotonin 2a (5-HT2a) receptor antagonist
  33. US regulatory status: approved. Molecular target: Cyclooxygenase.

    Target
    Cyclooxygenase
    Mechanism
    Cyclooxygenase inhibitor
  34. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Norepinephrine transporter inhibitor.

    Mechanism
    Norepinephrine transporter inhibitor
  35. US regulatory status: approved. Molecular target: Sodium-dependent noradrenaline transporter.

    Target
    Sodium-dependent noradrenaline transporter
    Mechanism
    Norepinephrine transporter inhibitor
  36. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  37. azathioprine

    Antineoplastic and immunomodulating agents (L04)

    US regulatory status: approved. Molecular target: Amidophosphoribosyltransferase.

    Target
    Amidophosphoribosyltransferase
    Mechanism
    Amidophosphoribosyltransferase inhibitor
  38. US regulatory status: approved. Molecular target: C55-isoprenyl pyrophosphate.

    Target
    C55-isoprenyl pyrophosphate
    Mechanism
    C55-isoprenyl pyrophosphate inhibitor
  39. US regulatory status: approved. Molecular target: GABA-B receptor.

    Target
    GABA-B receptor
    Mechanism
    GABA-B receptor agonist
  40. US regulatory status: approved. Molecular target: Glucocorticoid receptor.

    Target
    Glucocorticoid receptor
    Mechanism
    Glucocorticoid receptor agonist
  41. bedaquiline

    Antiinfectives for systemic use (J04)

    Antiinfectives for systemic use (J04) compound in BRIGHT MINDS BIOSCIENCES's portfolio.

  42. US regulatory status: approved. Molecular target: ATP synthase.

    Target
    ATP synthase
    Mechanism
    ATP synthase inhibitor
  43. US regulatory status: approved. Molecular target: Acetylcholinesterase.

    Target
    Acetylcholinesterase
    Mechanism
    Acetylcholinesterase inhibitor
  44. US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  45. besilesomab

    Various (V09)

    Various (V09) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Diagnostic agent.

    Mechanism
    Diagnostic agent
  46. bevacizumab

    Antineoplastic and immunomodulating agents (L01)

    US regulatory status: approved. Molecular target: Vascular endothelial growth factor A, long form.

    Target
    Vascular endothelial growth factor A, long form
    Mechanism
    Vascular endothelial growth factor A inhibitor
  47. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  48. US regulatory status: approved. Molecular target: DNA.

    Target
    DNA
    Mechanism
    DNA inhibitor
  49. US regulatory status: approved. Molecular target: DNA polymerase.

    Target
    DNA polymerase
    Mechanism
    DNA polymerase inhibitor
  50. US regulatory status: approved. Molecular target: Cyclooxygenase.

    Target
    Cyclooxygenase
    Mechanism
    Cyclooxygenase inhibitor
  51. buprenorphine

    Nervous system (N07)

    US regulatory status: approved. Molecular target: Kappa-type opioid receptor.

    Target
    Kappa-type opioid receptor
    Mechanism
    Kappa opioid receptor agonist
  52. US regulatory status: approved. Molecular target: Kappa-type opioid receptor.

    Target
    Kappa-type opioid receptor
    Mechanism
    Mu opioid receptor agonist
  53. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Dopamine transporter inhibitor.

    Mechanism
    Dopamine transporter inhibitor
  54. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Dopamine transporter inhibitor
  55. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Dopamine transporter inhibitor
  56. US regulatory status: approved. Molecular target: 5-hydroxytryptamine receptor 1A.

    Target
    5-hydroxytryptamine receptor 1A
    Mechanism
    Serotonin 1a (5-HT1a) receptor partial agonist
  57. caffeine

    Nervous system (N06)

    US regulatory status: approved. Molecular target: Adenosine receptor.

    Target
    Adenosine receptor
    Mechanism
    Adenosine receptor antagonist
  58. caffeine citrate

    Nervous system (N06)

    US regulatory status: approved. Molecular target: Adenosine receptor.

    Target
    Adenosine receptor
    Mechanism
    Adenosine receptor antagonist
  59. US regulatory status: approved.

  60. US regulatory status: approved. Mechanism: Dihydrofolate reductase inhibitor.

    Mechanism
    Dihydrofolate reductase inhibitor
  61. US regulatory status: approved. Mechanism: Surfactant agent.

    Mechanism
    Surfactant agent
  62. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Molecular target: Type-1 angiotensin II receptor.

    Target
    Type-1 angiotensin II receptor
    Mechanism
    Type-1 angiotensin II receptor antagonist
  63. cannabidiol

    Nervous system (N03)

    US regulatory status: approved. Molecular target: Cannabinoid receptor 1.

    Target
    Cannabinoid receptor 1
    Mechanism
    Cannabinoid CB1 receptor negative allosteric modulator
  64. capsaicin

    Nervous system (N01)

    US regulatory status: approved. Molecular target: Transient receptor potential cation channel subfamily V member 1.

    Target
    Transient receptor potential cation channel subfamily V member 1
    Mechanism
    Vanilloid receptor opener
  65. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  66. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  67. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  68. US regulatory status: approved. Molecular target: Sodium channel alpha subunit.

    Target
    Sodium channel alpha subunit
    Mechanism
    Sodium channel alpha subunit blocker
  69. US regulatory status: approved. Molecular target: Aromatic-L-amino-acid decarboxylase.

    Target
    Aromatic-L-amino-acid decarboxylase
    Mechanism
    DOPA decarboxylase inhibitor
  70. US regulatory status: approved. Molecular target: DNA.

    Target
    DNA
    Mechanism
    DNA inhibitor
  71. cariprazine

    Nervous system (N05)

    Nervous system (N05) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Dopamine D3 receptor modulator.

    Mechanism
    Dopamine D3 receptor modulator
  72. US regulatory status: approved. Molecular target: D(2) dopamine receptor.

    Target
    D(2) dopamine receptor
    Mechanism
    Dopamine D2 receptor modulator
  73. US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  74. US regulatory status: approved. Molecular target: Adrenergic receptor alpha-1.

    Target
    Adrenergic receptor alpha-1
    Mechanism
    Adrenergic receptor beta antagonist
  75. cefepime

    Antiinfectives for systemic use (J01)

    Antiinfectives for systemic use (J01) compound in BRIGHT MINDS BIOSCIENCES's portfolio.

  76. US regulatory status: approved. Molecular target: Bacterial penicillin-binding protein.

    Target
    Bacterial penicillin-binding protein
    Mechanism
    Bacterial penicillin-binding protein inhibitor
  77. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  78. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Histamine H1 receptor antagonist.

    Mechanism
    Histamine H1 receptor antagonist
  79. US regulatory status: approved. Molecular target: Histamine H1 receptor.

    Target
    Histamine H1 receptor
    Mechanism
    Histamine H1 receptor antagonist
  80. US regulatory status: approved. Molecular target: Cell membrane.

    Target
    Cell membrane
    Mechanism
    Cell membrane inhibitor
  81. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  82. cidofovir

    Antiinfectives for systemic use (J05)

    US regulatory status: approved. Molecular target: DNA polymerase catalytic subunit.

    Target
    DNA polymerase catalytic subunit
    Mechanism
    Human herpesvirus 1 DNA polymerase inhibitor
  83. US regulatory status: approved. Molecular target: Histamine H2 receptor.

    Target
    Histamine H2 receptor
    Mechanism
    Histamine H2 receptor antagonist
  84. cinacalcet

    Systemic hormonal preparations (H05)

    Systemic hormonal preparations (H05) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Calcium sensing receptor positive allosteric modulator.

    Mechanism
    Calcium sensing receptor positive allosteric modulator
  85. US regulatory status: approved. Molecular target: Bacterial DNA gyrase.

    Target
    Bacterial DNA gyrase
    Mechanism
    Bacterial DNA gyrase inhibitor
  86. US regulatory status: approved. Molecular target: Bacterial DNA gyrase.

    Target
    Bacterial DNA gyrase
    Mechanism
    Bacterial DNA gyrase inhibitor
  87. US regulatory status: approved. Molecular target: DNA.

    Target
    DNA
    Mechanism
    DNA inhibitor
  88. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Serotonin transporter inhibitor.

    Mechanism
    Serotonin transporter inhibitor
  89. US regulatory status: approved. Molecular target: Sodium-dependent serotonin transporter.

    Target
    Sodium-dependent serotonin transporter
    Mechanism
    Serotonin transporter inhibitor
  90. US regulatory status: approved. Molecular target: Bacterial 70S ribosome.

    Target
    Bacterial 70S ribosome
    Mechanism
    Bacterial 70S ribosome inhibitor
  91. US regulatory status: approved. Molecular target: GABA-A receptor; anion channel.

    Target
    GABA-A receptor; anion channel
    Mechanism
    GABA-A receptor; anion channel positive allosteric modulator
  92. US regulatory status: approved. Molecular target: Adrenergic receptor alpha-2.

    Target
    Adrenergic receptor alpha-2
    Mechanism
    Adrenergic receptor alpha-2 agonist
  93. clopidogrel

    Blood and blood forming organs (B01)

    Blood and blood forming organs (B01) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Purinergic receptor P2Y12 antagonist.

    Mechanism
    Purinergic receptor P2Y12 antagonist
  94. US regulatory status: approved. Molecular target: P2Y purinoceptor 12.

    Target
    P2Y purinoceptor 12
    Mechanism
    Purinergic receptor P2Y12 antagonist
  95. US regulatory status: approved. Molecular target: D(2) dopamine receptor.

    Target
    D(2) dopamine receptor
    Mechanism
    Serotonin 2a (5-HT2a) receptor antagonist
  96. US regulatory status: approved. Molecular target: Sodium channel alpha subunit.

    Target
    Sodium channel alpha subunit
    Mechanism
    Sodium channel alpha subunit blocker
  97. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  98. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  99. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  100. US regulatory status: approved. Molecular target: Glucocorticoid receptor.

    Target
    Glucocorticoid receptor
    Mechanism
    Glucocorticoid receptor agonist
  101. covid-19 vaccine (inactivated, adjuvanted, adsorbed)

    Antiinfectives for systemic use (J07)

    Antiinfectives for systemic use (J07) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Biological vaccine - induces immune response.

    Mechanism
    Biological vaccine - induces immune response
  102. US regulatory status: approved. Molecular target: Alanine racemase.

    Target
    Alanine racemase
    Mechanism
    Alanine racemase inhibitor
  103. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Molecular target: Prothrombin.

    Target
    Prothrombin
    Mechanism
    Thrombin inhibitor
  104. deferiprone

    Various (V03)

    US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  105. delamanid

    Antiinfectives for systemic use (J04)

    Antiinfectives for systemic use (J04) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Molecular target: Mycobacterium tuberculosis H37Rv.

    Target
    Mycobacterium tuberculosis H37Rv
    Mechanism
    Mycobacterium tuberculosis H37Rv inhibitor
  106. dengue tetravalent vaccine (live, attenuated)

    Antiinfectives for systemic use (J07)

    Antiinfectives for systemic use (J07) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Biological vaccine - induces immune response.

    Mechanism
    Biological vaccine - induces immune response
  107. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  108. US regulatory status: approved. Molecular target: Sodium-dependent noradrenaline transporter.

    Target
    Sodium-dependent noradrenaline transporter
    Mechanism
    Norepinephrine transporter inhibitor
  109. US regulatory status: approved. Molecular target: Mineralocorticoid receptor.

    Target
    Mineralocorticoid receptor
    Mechanism
    Mineralocorticoid receptor agonist
  110. US regulatory status: approved. Molecular target: Sodium-dependent noradrenaline transporter.

    Target
    Sodium-dependent noradrenaline transporter
    Mechanism
    Norepinephrine transporter inhibitor
  111. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Dopamine transporter releasing agent
  112. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Norepinephrine transporter releasing agent
  113. US regulatory status: approved. Molecular target: Cyclooxygenase.

    Target
    Cyclooxygenase
    Mechanism
    Cyclooxygenase inhibitor
  114. US regulatory status: approved. Molecular target: Sodium-dependent dopamine transporter.

    Target
    Sodium-dependent dopamine transporter
    Mechanism
    Norepinephrine transporter inhibitor
  115. diflunisal

    Nervous system (N02)

    US regulatory status: approved. Molecular target: Cyclooxygenase.

    Target
    Cyclooxygenase
    Mechanism
    Cyclooxygenase inhibitor
  116. US regulatory status: approved. Molecular target: Histamine H1 receptor.

    Target
    Histamine H1 receptor
    Mechanism
    Histamine H1 receptor antagonist
  117. US regulatory status: approved. Molecular target: Adrenergic receptor.

    Target
    Adrenergic receptor
    Mechanism
    Adrenergic receptor agonist
  118. US regulatory status: approved. Molecular target: Aldehyde dehydrogenase, mitochondrial.

    Target
    Aldehyde dehydrogenase, mitochondrial
    Mechanism
    Aldehyde dehydrogenase inhibitor
  119. US regulatory status: approved. Molecular target: Succinate-semialdehyde dehydrogenase, mitochondrial.

    Target
    Succinate-semialdehyde dehydrogenase, mitochondrial
    Mechanism
    Succinate semialdehyde dehydrogenase inhibitor
  120. docetaxel

    Antineoplastic and immunomodulating agents (L01)

    US regulatory status: approved. Molecular target: Tubulin.

    Target
    Tubulin
    Mechanism
    Tubulin inhibitor
  121. dodecafluoropentane

    Various (V08)

    Various (V08) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Ultrasound contrast agent.

    Mechanism
    Ultrasound contrast agent
  122. dofetilide

    Cardiovascular system (C01)

    US regulatory status: approved. Molecular target: Voltage-gated inwardly rectifying potassium channel KCNH2.

    Target
    Voltage-gated inwardly rectifying potassium channel KCNH2
    Mechanism
    HERG blocker
  123. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Acetylcholinesterase inhibitor.

    Mechanism
    Acetylcholinesterase inhibitor
  124. US regulatory status: approved. Molecular target: Acetylcholinesterase.

    Target
    Acetylcholinesterase
    Mechanism
    Acetylcholinesterase inhibitor
  125. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  126. US regulatory status: approved. Molecular target: Adrenergic receptor alpha-1.

    Target
    Adrenergic receptor alpha-1
    Mechanism
    Adrenergic receptor alpha-1 antagonist
  127. doxorubicin

    Antineoplastic and immunomodulating agents (L01)

    Antineoplastic and immunomodulating agents (L01) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: DNA topoisomerase II alpha inhibitor.

    Mechanism
    DNA topoisomerase II alpha inhibitor
  128. US regulatory status: approved. Molecular target: Cannabinoid receptor 1.

    Target
    Cannabinoid receptor 1
    Mechanism
    Cannabinoid CB1 receptor agonist
  129. empagliflozin

    Alimentary tract and metabolism (A10)

    US regulatory status: approved. Molecular target: Sodium/glucose cotransporter 2.

    Target
    Sodium/glucose cotransporter 2
    Mechanism
    Sodium/glucose cotransporter 2 inhibitor
  130. emtricitabine

    Antiinfectives for systemic use (J05)

    US regulatory status: approved. Molecular target: Human immunodeficiency virus type 1 reverse transcriptase.

    Target
    Human immunodeficiency virus type 1 reverse transcriptase
    Mechanism
    Human immunodeficiency virus type 1 reverse transcriptase inhibitor
  131. entacapone

    Nervous system (N04)

    US regulatory status: approved. Molecular target: Catechol O-methyltransferase.

    Target
    Catechol O-methyltransferase
    Mechanism
    Catechol O-methyltransferase inhibitor
  132. entecavir

    Antiinfectives for systemic use (J05)

    US regulatory status: approved. Molecular target: DNA polymerase/reverse transcriptase.

    Target
    DNA polymerase/reverse transcriptase
    Mechanism
    DNA polymerase/reverse transcriptase inhibitor
  133. enzalutamide

    Antineoplastic and immunomodulating agents (L02)

    US regulatory status: approved. Molecular target: Androgen receptor.

    Target
    Androgen receptor
    Mechanism
    Androgen Receptor antagonist
  134. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  135. US regulatory status: approved. Molecular target: Vitamin D3 receptor.

    Target
    Vitamin D3 receptor
    Mechanism
    Vitamin D receptor agonist
  136. US regulatory status: approved. Molecular target: Bacterial 70S ribosome.

    Target
    Bacterial 70S ribosome
    Mechanism
    Bacterial 70S ribosome inhibitor
  137. US regulatory status: approved. Molecular target: Bacterial 70S ribosome.

    Target
    Bacterial 70S ribosome
    Mechanism
    Bacterial 70S ribosome inhibitor
  138. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  139. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Serotonin transporter inhibitor.

    Mechanism
    Serotonin transporter inhibitor
  140. US regulatory status: approved. Molecular target: Sodium-dependent serotonin transporter.

    Target
    Sodium-dependent serotonin transporter
    Mechanism
    Serotonin transporter inhibitor
  141. US regulatory status: approved. Molecular target: Glutamate [NMDA] receptor.

    Target
    Glutamate [NMDA] receptor
    Mechanism
    Glutamate [NMDA] receptor negative allosteric modulator
  142. US regulatory status: approved. Molecular target: Estrogen receptor.

    Target
    Estrogen receptor
    Mechanism
    Estrogen receptor alpha agonist
  143. US regulatory status: approved. Molecular target: GABA-A receptor; anion channel.

    Target
    GABA-A receptor; anion channel
    Mechanism
    GABA-A receptor; anion channel positive allosteric modulator
  144. US regulatory status: approved. Molecular target: GABA-A receptor; anion channel.

    Target
    GABA-A receptor; anion channel
    Mechanism
    GABA-A receptor; anion channel positive modulator
  145. US regulatory status: approved. Molecular target: Estrogen receptor.

    Target
    Estrogen receptor
    Mechanism
    Estrogen receptor alpha agonist
  146. everolimus

    Antineoplastic and immunomodulating agents (L01)

    US regulatory status: approved. Molecular target: Peptidyl-prolyl cis-trans isomerase FKBP1A.

    Target
    Peptidyl-prolyl cis-trans isomerase FKBP1A
    Mechanism
    FK506-binding protein 1A inhibitor
  147. evolocumab

    Cardiovascular system (C10)

    US regulatory status: approved. Molecular target: Proprotein convertase subtilisin/kexin type 9.

    Target
    Proprotein convertase subtilisin/kexin type 9
    Mechanism
    Subtilisin/kexin type 9 inhibitor
  148. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  149. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  150. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Molecular target: RNA-directed RNA polymerase.

    Target
    RNA-directed RNA polymerase
    Mechanism
    RNA-directed RNA polymerase inhibitor
  151. fenfluramine

    Nervous system (N03)

    US regulatory status: approved. Mechanism: Serotonin 2c (5-HT2c) receptor agonist.

    Mechanism
    Serotonin 2c (5-HT2c) receptor agonist
  152. fentanyl

    Nervous system (N02)

    US regulatory status: approved. Molecular target: Mu-type opioid receptor.

    Target
    Mu-type opioid receptor
    Mechanism
    Mu opioid receptor agonist
  153. US regulatory status: approved. Molecular target: Mu-type opioid receptor.

    Target
    Mu-type opioid receptor
    Mechanism
    Mu opioid receptor agonist
  154. ferumoxytol

    Blood and blood forming organs (B03)

    US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  155. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Histamine H1 receptor antagonist.

    Mechanism
    Histamine H1 receptor antagonist
  156. US regulatory status: approved. Molecular target: Histamine H1 receptor.

    Target
    Histamine H1 receptor
    Mechanism
    Histamine H1 receptor antagonist
  157. fingolimod

    Antineoplastic and immunomodulating agents (L04)

    US regulatory status: approved. Mechanism: Sphingosine 1-phosphate receptor binding agent.

    Mechanism
    Sphingosine 1-phosphate receptor binding agent
  158. florbetapir (18f)

    Various (V09)

    Various (V09) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Diagnostic agent.

    Mechanism
    Diagnostic agent
  159. US regulatory status: approved. Mechanism: Diagnostic agent.

    Mechanism
    Diagnostic agent
  160. flortaucipir (18f)

    Various (V09)

    Various (V09) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Diagnostic agent.

    Mechanism
    Diagnostic agent
  161. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  162. US regulatory status: approved. Molecular target: GABA-A receptor; anion channel.

    Target
    GABA-A receptor; anion channel
    Mechanism
    GABA-A receptor; anion channel allosteric antagonist
  163. US regulatory status: approved. Mechanism: Diagnostic agent.

    Mechanism
    Diagnostic agent
  164. US regulatory status: approved. Molecular target: Sodium-dependent serotonin transporter.

    Target
    Sodium-dependent serotonin transporter
    Mechanism
    Serotonin transporter inhibitor
  165. US regulatory status: approved. Molecular target: Glucocorticoid receptor.

    Target
    Glucocorticoid receptor
    Mechanism
    Glucocorticoid receptor agonist
  166. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  167. fondaparinux sodium

    Blood and blood forming organs (B01)

    US regulatory status: approved. Molecular target: Antithrombin-III.

    Target
    Antithrombin-III
    Mechanism
    Antithrombin-III activator
  168. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  169. US regulatory status: approved. Molecular target: Voltage-gated calcium channel.

    Target
    Voltage-gated calcium channel
    Mechanism
    Voltage-gated calcium channel modulator
  170. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Mechanism: Acetylcholinesterase inhibitor.

    Mechanism
    Acetylcholinesterase inhibitor
  171. US regulatory status: approved. Mechanism: DNA polymerase (alpha/delta/epsilon) inhibitor.

    Mechanism
    DNA polymerase (alpha/delta/epsilon) inhibitor
  172. US regulatory status: approved. Molecular target: Peroxisome proliferator-activated receptor alpha.

    Target
    Peroxisome proliferator-activated receptor alpha
    Mechanism
    Peroxisome proliferator-activated receptor alpha agonist
  173. US regulatory status: approved. Molecular target: Bacterial 70S ribosome.

    Target
    Bacterial 70S ribosome
    Mechanism
    Bacterial 70S ribosome inhibitor
  174. US regulatory status: approved. Molecular target: 5-hydroxytryptamine receptor 1A.

    Target
    5-hydroxytryptamine receptor 1A
    Mechanism
    Serotonin 1a (5-HT1a) receptor agonist
  175. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records. Molecular target: Sulfonylurea receptor 1, Kir6.2.

    Target
    Sulfonylurea receptor 1, Kir6.2
    Mechanism
    Sulfonylurea receptor 1, Kir6.2 blocker
  176. US regulatory status: approved. Molecular target: Sulfonylurea receptor 1, Kir6.2.

    Target
    Sulfonylurea receptor 1, Kir6.2
    Mechanism
    Sulfonylurea receptor 1, Kir6.2 blocker
  177. US regulatory status: approved. Molecular target: Gonadotropin-releasing hormone receptor.

    Target
    Gonadotropin-releasing hormone receptor
    Mechanism
    Gonadotropin-releasing hormone receptor agonist
  178. US regulatory status: approved. Molecular target: Gonadotropin-releasing hormone receptor.

    Target
    Gonadotropin-releasing hormone receptor
    Mechanism
    Gonadotropin-releasing hormone receptor agonist
  179. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  180. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  181. Development asset linked to BRIGHT MINDS BIOSCIENCES in public FDA and regional records.

  182. guanfacine

    Cardiovascular system (C02)

    Cardiovascular system (C02) compound in BRIGHT MINDS BIOSCIENCES's portfolio. Mechanism: Adrenergic receptor alpha-2 agonist.

    Mechanism
    Adrenergic receptor alpha-2 agonist
  183. US regulatory status: approved. Molecular target: Adrenergic receptor alpha-2.

    Target
    Adrenergic receptor alpha-2
    Mechanism
    Adrenergic receptor alpha-2 agonist
  184. guselkumab

    Antineoplastic and immunomodulating agents (L04)

    US regulatory status: approved. Molecular target: Interleukin-23.

    Target
    Interleukin-23
    Mechanism
    Interleukin-23 inhibitor