Wednesday, July 8, 2026

pharma · Locally advanced or metastatic urothelial cancer · Nectin-4 Expressing Advanced Malignancies. · BCYC

BICYCLE THERAPEUTICS

BICYCLE THERAPEUTICS drug portfolio — 15 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Cambridge, GB HQ
2009 Founded
282 Employees
Public company Type
BCYC · NYSE Ticker
Company details
Status
Public
HQ
Cambridge, GB
Founded
2009
Employees
282
Programs
8
Drugs
15
Patents
57
Intelligence · Drug Pipeline

BICYCLE THERAPEUTICS pipeline

Portfolio lens on 15 drugs and development assets — regulatory status, targets, and deep links to NovaPharmaNews drug profiles.

BICYCLE THERAPEUTICS drug portfolio — 15 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Drug portfolio

15 compounds
  1. avelumab

    Antineoplastic and immunomodulating agents (L01)

    US regulatory status: approved. Molecular target: Programmed cell death 1 ligand 1.

    Target
    Programmed cell death 1 ligand 1
    Mechanism
    Programmed cell death 1 ligand 1 other
  2. buprenorphine

    Nervous system (N07)

    US regulatory status: approved. Molecular target: Kappa-type opioid receptor.

    Target
    Kappa-type opioid receptor
    Mechanism
    Kappa opioid receptor agonist
  3. US regulatory status: approved. Molecular target: DNA.

    Target
    DNA
    Mechanism
    DNA inhibitor
  4. US regulatory status: approved. Molecular target: Histamine H2 receptor.

    Target
    Histamine H2 receptor
    Mechanism
    Histamine H2 receptor antagonist
  5. US regulatory status: approved. Molecular target: Histamine H2 receptor.

    Target
    Histamine H2 receptor
    Mechanism
    Histamine H2 receptor antagonist
  6. US regulatory status: approved. Molecular target: DNA.

    Target
    DNA
    Mechanism
    DNA inhibitor
  7. US regulatory status: approved. Molecular target: Sphingosine 1-phosphate receptor.

    Target
    Sphingosine 1-phosphate receptor
    Mechanism
    Sphingosine 1-phosphate receptor binding agent
  8. US regulatory status: approved. Mechanism: DNA polymerase (alpha/delta/epsilon) inhibitor.

    Mechanism
    DNA polymerase (alpha/delta/epsilon) inhibitor
  9. US regulatory status: approved. Molecular target: Opioid receptors; mu/kappa/delta.

    Target
    Opioid receptors; mu/kappa/delta
    Mechanism
    Opioid receptors; mu/kappa/delta antagonist
  10. nivolumab

    Antineoplastic and immunomodulating agents (L01)

    US regulatory status: approved. Molecular target: Programmed cell death protein 1.

    Target
    Programmed cell death protein 1
    Mechanism
    Programmed cell death protein 1 inhibitor
  11. pembrolizumab

    Antineoplastic and immunomodulating agents (L01)

    US regulatory status: approved. Molecular target: Programmed cell death protein 1.

    Target
    Programmed cell death protein 1
    Mechanism
    Programmed cell death protein 1 inhibitor
  12. US regulatory status: approved. Molecular target: Sodium channel alpha subunit.

    Target
    Sodium channel alpha subunit
    Mechanism
    Sodium channel alpha subunit blocker
  13. US regulatory status: approved. Molecular target: Sodium channel alpha subunit.

    Target
    Sodium channel alpha subunit
    Mechanism
    Sodium channel alpha subunit blocker
  14. US regulatory status: approved. Molecular target: Synaptic vesicular amine transporter.

    Target
    Synaptic vesicular amine transporter
    Mechanism
    Synaptic vesicular amine transporter inhibitor