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Flow Chemistry Equipment

Vapourtec | Flow Chemistry Systems for Pharmaceutical R&D

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Overview

Vapourtec develops and manufactures benchtop flow chemistry systems and reactors for pharmaceutical research and development. Their product portfolio includes the E-Series and R-Series modular platforms, specialized reactors for electrochemistry and peptide synthesis, and integrated components for continuous processing. The company enables scalable, automated chemical reactions with precise thermal control and compatibility with sensitive reagents including organometallics and strong acids.

Frequently asked questions

What flow chemistry systems does Vapourtec offer for pharmaceutical applications?
Vapourtec offers two main system lines: the E-Series, a robust entry-level system for pumping strong acids/bases, light slurries, and sensitive reagents; and the R-Series, a modular high-performance platform that operates autonomously or integrates with other equipment for automated flow chemistry experiments. Both systems support benchtop flow chemistry with precise control capabilities.
What specialized reactors are available for pharmaceutical synthesis?
Vapourtec provides multiple specialized reactors including the Ion electrochemical reactor for continuous flow electrochemistry (operating up to 5 bar, temperature range -10°C to 100°C), cooled tube reactors with dry ice-cooled nitrogen for low-temperature reactions, and the Variable Bed Flow Reactor (VBFR) for peptide synthesis supporting chains up to 120 amino acids with faster coupling-deprotection cycles and reduced solvent consumption.
What temperature control capabilities do Vapourtec systems provide?
Temperature control varies by component: the Ion electrochemical reactor operates between -10°C and 100°C when integrated with E-Series or R-Series systems; the SF-10+ pump can be heated between ambient and 80°C with heated inlet/outlet tubes; and cooled tube reactors achieve low temperatures using dry ice-cooled nitrogen generation without requiring external chillers, with fully programmable setpoints.
Does Vapourtec support liquid-liquid separation in flow chemistry workflows?
Yes, Vapourtec has partnered with Zaiput Flow Technologies to integrate liquid-liquid separation capabilities into their flow chemistry product offerings, expanding their continuous processing capabilities for pharmaceutical applications requiring phase separation.
What are the key advantages of Vapourtec's peptide synthesis platform?
The VBFR-based peptide synthesis platform enables access to longer peptides and small proteins (50-120 amino acids), faster coupling-deprotection-wash cycles, lower excess reagent requirements, reduced solvent consumption for resin washing, and higher quality real-time data including resin volume monitoring compared to traditional batch methods.