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Syndex Bio

Syndex Bio: mcPCR for DNA Methylation Analysis

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Overview

Syndex Bio develops the proprietary mcPCR platform, which enables high-fidelity amplification of both DNA methylation patterns and genetic sequences, overcoming limitations of traditional PCR. This technology supports sensitive analysis of methylated DNA in clinical samples, particularly for non-invasive biopsies in early disease detection and cancer monitoring. Based in Cambridge, UK, the company recently raised $15.5M in seed funding to expand R&D and clinical applications.

Frequently asked questions

What is Syndex Bio's main technology offering?
Syndex Bio's mcPCR platform preserves DNA methylation patterns during amplification, enabling PCR-like copying of both methylation marks and the four-base genetic code for high-sensitivity analysis.
What applications does mcPCR support?
mcPCR supports research and clinical workflows for analyzing methylated DNA in non-invasive and small-sample biopsies, aiding early disease detection, cancer recurrence monitoring, and molecular diagnostics.
Where is Syndex Bio located and what is their funding status?
Syndex Bio is based at Melbourn Science Park in Cambridge, UK, and raised an oversubscribed $15.5M seed round led by ARCH Venture Partners to expand the mcPCR platform and R&D.