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Stellaromics

Stellaromics: 3D Spatial Multi-Omics Platform

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Overview

Stellaromics offers the Pyxa platform, the first commercial system for high-plex 3D spatial multi-omics in intact tissue up to 100 micrometers thick. It enables subcellular-resolution mapping of gene expression, proteins, and active translation using technologies like STARmap, RIBOmap, and STARmap PLUS. The integrated solution includes sample preparation, automated confocal imaging, and PyxaStudio software for visualization and analysis, supporting pharma R&D in resolving complex tissue organization and disease mechanisms.

Frequently asked questions

What capabilities does the Pyxa platform offer?
Pyxa provides high-plex confocal imaging for 3D spatial multi-omics, capturing single-cell gene expression, proteins, and translation in intact tissue up to 100 µm thick with subcellular detail and custom panels.
What technologies power Stellaromics' spatial analysis?
The platform uses STARmap for transcripts, RIBOmap for active translation, and STARmap PLUS for proteins, enabling multi-omic analysis while preserving native 3D tissue structure.
Where is Stellaromics located and who founded it?
Headquartered in Boston, Massachusetts, USA, Stellaromics was spun out from labs of Karl Deisseroth (Stanford) and Xiao Wang (MIT/Broad Institute).