CDMO & Manufacturing

Ori Biotech offers the IRO platform, a proprietary system that automates, standardizes, and scales cell and gene therapy (CGT) manufacturing, particularly for cell therapies like CAR-T. The compact, flexible platform reduces costs, processing times, and labor while improving quality through integrated hardware, software, and data services. It supports end-to-end workflows from preclinical development to commercial scale and integrates with partner technologies for closed, efficient processing.

Paragon Medical provides contract design, manufacturing, and development services for medical devices, specializing in orthopaedics, surgical instruments, implants, and drug delivery components. They offer end-to-end solutions from concept and prototyping to regulatory support, precision machining, assembly, and packaging in FDA-registered, ISO 8 cleanroom facilities. With global campuses and expertise in advanced technologies like additive manufacturing and micromachining, they support pharma and life sciences in accelerating product development and streamlining supply chains.

Particleworks is a particle-based Computational Fluid Dynamics (CFD) software using the Moving Particle Simulation (MPS) method for advanced fluid dynamics modeling. The software enables simulation of complex fluid behaviors including multiphase flow, large deformations, conjugate heat transfer, and fluid-structure interactions without requiring mesh generation. Applications span pharmaceutical manufacturing, bioprocessing, and laboratory equipment design where precise fluid dynamics modeling is critical.

Emerson provides automation technologies and process control solutions for pharmaceutical manufacturing, enabling real-time monitoring of product quality and efficacy. They offer scalable automation software for continuous manufacturing of oral solid dose pharmaceuticals, partnering with companies like IMA Active to improve production efficiency. Emerson supports operations management, electronic batch record systems, and regulatory compliance throughout the production process.

Dassault Systèmes provides digital solutions for pharmaceutical and biotech companies, covering concept to manufacturing, clinical trials, and supply chain optimization. Their 3DEXPERIENCE platform enables virtualization, simulation, and data-driven decisions to ensure high-quality production as designed and registered. Solutions include agile production scheduling to improve delivery times and resource optimization, alongside molecular modeling for drug development.

Evotec SE is a global drug discovery and development company headquartered in Hamburg, Germany, offering integrated solutions from target-to-clinic, including small molecules, biologics, and cell therapies. They provide expertise in proteomics, metabolomics, chemical biology, and biomarker discovery through sites like Munich. Evotec also supports drug substance manufacturing via Evotec DS in Germany and biologics development through Just – Evotec Biologics.

ProBioGen AG is a Berlin-based CDMO specializing in cell line engineering, process development, and GMP manufacturing of biopharmaceuticals including proteins, antibodies, viral vectors, and vaccines. They offer proprietary technologies like GlymaxX® for afucosylated antibodies enhancing ADCC efficacy. Services are supported by a GMP-compliant quality system meeting EMA/FDA standards with up to 1000L bioreactor capacity.

Promega offers over 4,000 products including reagents, kits, and instruments for cell biology, nucleic acid analysis, protein research, drug discovery, human identification, and molecular diagnostics. The company provides solutions for biologics drug discovery, custom assay development, and manufacturing services to support pharma R&D and production. Global technical support and custom workflows accelerate customer projects in life sciences.

ProteoNic Biosciences provides premium vector and transposon technology, including the 2G UNic® platform, to boost protein production in mammalian, yeast, and fungal cells for biopharmaceutical manufacturing. Their solutions enhance expression of complex proteins like multi-specific antibodies, fusion proteins, and viral vectors, improving productivity and titers. The company supports biologics R&D and production, with recent licensing of 2G UNic® to Ginkgo Bioworks for BARDA-funded anti-filovirus therapies.

Protheragen-ING supplies active pharmaceutical ingredients (APIs) for anti-tumor, hypoglycemic, antipsychotic, bronchiectasis, and antihypertensive applications, alongside pharmaceutical excipients, intermediates, and veterinary products. It offers AI-powered drug discovery services including target identification, candidate optimization, drug repositioning, high-throughput screening, and AI synthesizers for small molecules and antibody drug conjugates. Additionally, Protheragen-ING Lab provides GLP-compliant lab synthesis, testing, medical device safety, biocompatibility, and validation services for pharmaceutical and biotech industries.

Provectus Algae develops scalable biomanufacturing platforms using photosynthetic microalgae and Precision Photosynthesis technology to produce high-value compounds for pharmaceuticals, nutraceuticals, and therapeutics. Their closed-system bioreactors enable controlled production of target substances like peptides, proteins, and bioactive ingredients for drug development and synthetic biology applications. The company supports R&D in sustainable bioproducts across food, cosmetics, agriculture, and pharma sectors.

RTS Consulting - Automation provides turnkey shop floor to top floor solutions for manufacturing excellence, with expertise in MES implementations, shop floor automation using PLCs, SCADA, and Historians, and control systems integration. Founded in 1992, the company assists industrial clients in developing and implementing SAP MII solutions through control panel design and build capabilities. Their services support manufacturing sectors potentially including life sciences and pharma automation needs.

ReiThera is an Italian CDMO specializing in process development and GMP manufacturing of viral vectors including AAV, Ad (GRAd platform), MVA, HSV, and LVV for gene therapies and vaccines. The company operates a state-of-the-art facility in Rome with bioreactors up to 2000-3000L scale, fixed-bed systems, fill/finish suites, and quality control labs, supporting end-to-end services from vector design to commercial production. Key platforms include ReiCell-AAV for scalable AAV production and validated MVA processes.

Rentschler Biopharma is a global leading CDMO specializing in full-service bioprocess development and cGMP manufacturing of high-quality biopharmaceuticals, including complex biologics and recombinant proteins. With over 50 years of experience, they offer expertise in process optimization, analytical and formulation development, and client program management across state-of-the-art facilities. Recent expansions include new production lines in Milford, Massachusetts, and buffer media manufacturing in Laupheim, Germany, to meet growing demand.

QIAGEN offers OEM and custom manufacturing solutions for life sciences and pharma, including bulk production of enzymes, oligos, buffers, kits, assays, and automation systems. With over 40 years of experience, they provide scalable, high-quality products from prototype to commercial scale through ISO and GMP-certified global facilities. Strategic partnerships enable rapid market entry while ensuring compliance, quality, and consistency.

Sartorius is a trusted partner for the biopharmaceutical industry and laboratories, offering solutions spanning drug discovery, development, and production platforms. The company provides filtration solutions, liquid handling instruments, integrated weighing systems, and contract manufacturing services. Sartorius operates manufacturing facilities across the Americas, Europe, and Asia, with significant US production capacity including operations in Puerto Rico and the East Coast.

Sartorius provides comprehensive laboratory equipment and bioprocess solutions for the biopharmaceutical industry, including pipettes, balances, filtration systems, cell culture media, and single-use products for drug discovery, development, and manufacturing. Their offerings span cell cultivation, fermentation, purification, fluid management, and process intensification to enhance efficiency, scalability, and compliance. As a global leader, they support pharmaceutical, biotech, and research labs in producing biologics, vaccines, and therapies.

ScaleReady is a strategic partnership providing scalable and cost-effective closed workflow solutions for immune cell therapy manufacturing. The platform integrates GMP cytokines, gene engineering capabilities, and G-Rex bioreactors to enable linear process scaling from development to commercial production. ScaleReady addresses manufacturing complexity by automating unit operations, reducing skilled personnel requirements, and supporting addressable patient populations of 30,000+ patients annually.

DrugBank provides a comprehensive biomedical knowledgebase with detailed data on drugs, targets, actions, interactions, and ADMET properties for drug discovery, repurposing, and R&D. It offers structured clinical and scientific data solutions used by pharma companies, healthcare software developers, and researchers worldwide. The platform includes AI-driven tools and APIs for precision medicine, electronic medical records, and clinical intelligence applications.

ProteoNic BioSciences offers proprietary vector technologies like 2G UNic™ to pharmaceutical, biotech, and CDMO companies for enhancing protein production, viral vector titers, and gene expression in mammalian, yeast, and fungal cells. The technology optimizes mRNA translation, boosts yields for complex proteins such as multi-specific antibodies, and lowers production costs through non-exclusive worldwide licensing. Validated across common expression platforms, it supports biologics and gene therapy manufacturing with customization options.

Takara Bio provides kits, reagents, instruments, and services for life science research in gene discovery, regulation, function, cancer therapy, NGS, and single-cell technologies. The company offers CDMO services for regenerative medicine, including GMP manufacturing for cellular and gene therapy products at facilities in Japan, the US, Europe, China, and India. Their portfolio supports applications like CAR-T therapy, immune profiling, vaccine development, and drug discovery.

Terumo Blood and Cell Technologies provides medical technologies for blood collection, processing, and cell-based therapies, including apheresis systems, blood bags, and automated cell expansion solutions like the Quantum system. They support hospitals, blood centers, researchers, and cell therapy developers with products for whole blood separation, pathogen reduction, and CAR-T cell manufacturing. Their offerings enhance efficiency in therapeutic apheresis and enable scalable cell and gene therapies globally.

Thermo Fisher Scientific provides end-to-end contract development and manufacturing organization (CDMO) services for pharmaceuticals, including APIs, biologics, viral vectors, cell and gene therapies, and small molecules from pre-clinical to commercialization. The company operates over 60 global sites with capabilities in sterile fill-finish, oral solid dose production, mRNA lipid nanoparticles, and clinical trial supply chain management. Recent expansions include Accelerator Drug Development solutions integrating CDMO, CRO, and logistics for biotech and large pharma.

Touchlight is a UK-based CDMO specializing in cell-free enzymatic DNA production using proprietary dbDNA™ technology, offering scalable, high-purity alternatives to plasmid DNA for genetic medicines. They support mRNA, viral and non-viral gene therapies, vaccines, and gene editing from preclinical to GMP stages. Their platform enables rapid manufacturing of grams of DNA with benchtop equipment, addressing limitations of traditional methods.