Friday, July 10, 2026

Intelligence · Clinical Development

Pipeline search results

Programs matching “dexmedetomidine” across our ClinicalTrials.gov index — phase, modality, sponsor, and trial IDs.

Matching programs 65
Total indexed 20,548
Sponsors 1,771

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Showing 65 pipeline programs matching "dexmedetomidine" from NovaPharmaNews Clinical Development Intelligence — phase, modality, sponsor, and ClinicalTrials.gov trial IDs.

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65 results for “dexmedetomidine” Back to intelligence hub

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  1. DEXMEDETOMIDINE , 18F-DPA-714

    Pari Pharma GmbH

    Patients who survive a COVID ARDS in intensive care must be weaned off invasive mechanical ventilation as quickly as possible. 60% of these patients present with intensive care delirium, a serious event that causes excess mortality and potential acute and late complications, since 30% of patients who present with delirium develop cognitive sequelae. Severe neuroinflammation is considered to be one of the main pathophysiological mechanisms causing delirium during ventilatory weaning. In addition to its sedative properties, dexmedetomidine has neuroprotective effects. In certain experimental models, it reduces cerebral inflammation by acting directly on the microglial phenotype. The role of this chronic neuroinflammatory state on cognitive capacity and reserve is beginning to emerge in the literature, regardless of the initial stress (surgery, head injury or Alzheimer's-type dementia), and is therefore capable of influencing patients' quality of life. The assessment of this neuroinflammation using non-invasive tools would appear to be of prime importance in the management of post-COVID neuro injured patients, as well as the evaluation of potential neuroprotective agents such as dexmedetomidine.

    phase 3 small molecule active

    1 trial
  2. Dexmedetomidine Hcl 100 Mcg/mL Inj

    Hospital Authority, Hong Kong

    Congenital Heart Disease in Children

    phase 3 small molecule completed

    1 trial
  3. PEDIADEX

    Tour Hekla

    Impact on delirium of the use of DEXmedetomidine as first-line sedation in PEDIAtric intensive care:

    phase 3 small molecule active

    1 trial
  4. SEVOFLURANE, DEXMEDETOMIDINE HYDROCHLORIDE

    The George Institute

    Children under the age of 2 years having surgery lasting at least 2 hours

    phase 3 small molecule active

    1 trial
  5. Sublingual film containing Dexmedetomidine (BXCL501)

    BioXcel Therapeutics

    Agitation Associated With Bipolar Disorder

    phase 3 small molecule completed

    1 trial
  6. Sublingual film containing dexmedetomidine (BXCL501)

    BioXcel Therapeutics

    Agitation

    phase 3 small molecule completed

    1 trial
  7. Caudal Dexmedetomidine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Inguinal Hernia

    phase 2 small molecule completed

    1 trial
  8. Dexmedetomidine

    BioXcel Therapeutics

    Opioid Withdrawal

    phase 2 small molecule completed

    1 trial
  9. Dexmedetomidine

    COGNITION THERAPEUTICS INC

    Alzheimer Disease

    phase 2 small molecule completed

    1 trial
  10. Dexmedetomidine injection

    Sana Biotechnology

    Post Spinal Shivering

    phase 2 small molecule active

    1 trial
  11. Dexmedetomidine sublingual film

    BioXcel Therapeutics

    Delirium

    phase 2 small molecule terminated

    1 trial
  12. Sublingual film containing Dexmedetomidine

    BioXcel Therapeutics

    Agitation,Psychomotor

    phase 2 small molecule completed

    1 trial
  13. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Heart Injuries

    phase 1 small molecule active

    1 trial
  14. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Cesarean Section, Affecting Fetus or Newborn

    phase 1 small molecule completed

    1 trial
  15. Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg

    BioXcel Therapeutics

    Alcohol Use Disorder (AUD)

    phase 1 small molecule active

    1 trial
  16. Sublingual film containing BXCL501 (Dexmedetomidine)

    BioXcel Therapeutics

    Agitation

    phase 1 small molecule completed

    1 trial
  17. 0.3% ropivacaine and 50 μg dexmedetomidine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Free Flap Reconstruction

    approved small molecule active

    1 trial
  18. Dexmedetomidine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lower Limb Fracture

    approved small molecule completed

    1 trial
  19. Dexmedetomidine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Post-Surgical Pain

    approved small molecule active

    1 trial
  20. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Elderly

    approved small molecule completed

    3 trials
  21. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Renal Function

    approved small molecule active

    1 trial
  22. Dexmedetomidine

    The University of Hong Kong

    Anxiety, Separation

    approved small molecule active

    1 trial
  23. Dexmedetomidine

    Hospital Authority, Hong Kong

    Thyroid Diseases

    approved small molecule active

    1 trial
  24. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Breast Cancer

    approved small molecule completed

    1 trial

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