Friday, July 10, 2026

Intelligence · Clinical pipeline

Oncology R&D Pipeline

Anticancer agents, immuno-oncology biologics, and oncology pipeline programs from ClinicalTrials.gov — Phase 1 through approval.

Programs 5,539

Quick answer

Oncology: NovaPharmaNews indexes 5,539 oncology clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. Anticancer agents, immuno-oncology biologics, and oncology pipeline programs from ClinicalTrials.gov — Phase 1 through approval.

Top sponsors

Pipeline programs

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  1. Pevonedistat 25 mg/m^2

    Takeda

    Leukemia, Myeloid, Acute

    phase 1 small molecule completed

    1 trial
  2. Ph 1 Study of ORIC-944 in Patients with Metastatic Prostate Cancer.

    Topiloric/Uriadec

    Prostate cancer

    phase 1 other active

    1 trial
  3. Phase 1 Study of IMC-P115C in Advanced PRAME Positive Cancers

    Immunocore Ireland Limited

    Advanced PRAME Positive Cancers

    phase 1 other active

    1 trial
  4. Phase 1 Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancer

    Janssen-Cilag International N.V.

    Metastatic colorectal cancer and Gastric cancer

    phase 1 other active

    1 trial
  5. Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

    Olema Pharmaceuticals

    Advanced or Metastatic Solid Tumors

    phase 1 other active

    1 trial
  6. Phase 1 Study of PYX-106 in Solid Tumors

    Pyxis Oncology

    Solid Tumors

    phase 1 other active

    1 trial
  7. Phase 1 Study of PYX-201 in Solid Tumors

    Pyxis Oncology

    Advanced solid tumors

    phase 1 other active

    1 trial
  8. Phase 1 trial of valemetostat and darolutamide in mCRPC

    Daiichi Sankyo

    Metastatic Castration Resistant Prostate Cancer (mCRPC)

    phase 1 other active

    1 trial
  9. Phase 1b Study of Tarlatamab + ZL-1310 +/- Anti-PD-L1 in Small Cell Lung Cancer

    Amgen

    Small Cell Lung Cancer

    phase 1 other active

    1 trial
  10. Phase I Study of PM54 Administered to Patients with Advanced Solid Tumors

    Lacuna Pharma Pty Ltd

    Selected Advanced Solid Tumors

    phase 1 other active

    1 trial
  11. Phase I study of 225Ac-PSMA I&T in prostate cancer

    Disc Medicine

    metastatic prostate cancer

    phase 1 other active

    1 trial
  12. Phase I study of MGY825 in patients with lung cancer

    Novartis Pharmaceuticals

    Advanced non-small cell lung cancer with or without NFE2L2/KEAP1/CUL3 mutations in adult patients

    phase 1 other active

    1 trial
  13. Pitavastatin

    United Therapeutics Europe Ltd

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial
  14. Placebo for antibiotic

    Seres Therapeutics

    Metastatic Melanoma

    phase 1 small molecule completed

    1 trial
  15. Plerixafor

    United Therapeutics Europe Ltd

    Pancreatic Adenocarcinoma Metastatic

    phase 1 small molecule completed

    1 trial
  16. Ponatinib

    Takeda

    Chronic Myelogenous Leukemia

    phase 1 small molecule completed

    1 trial
  17. Prizloncabtagene Autoleucel

    The First People's Hospital of Lianyungang

    Non-Hodgkin's B-cell Lymphoma

    phase 1 mab active

    1 trial
  18. Proxalutamide

    The First People's Hospital of Lianyungang

    Metastatic Breast Cancer

    phase 1 small molecule completed

    1 trial
  19. Pyrotinib low dose group

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Cancer

    phase 1 small molecule active

    1 trial
  20. QEQ278

    Novartis Pharmaceuticals

    Carcinoma, Non-Small-Cell Lung

    phase 1 mab terminated

    1 trial
  21. R1979-HM-1333

    Lacuna Pharma Pty Ltd

    B-cell non-Hodgkin lymphoma (NHL)

    phase 1 other active

    1 trial
  22. R1979-ONC-1504

    Lacuna Pharma Pty Ltd

    B-Cell Non-Hodgkin’s Lymphoma (B-NHL)

    phase 1 other active

    1 trial
  23. R2810-ONC-1787

    Lacuna Pharma Pty Ltd

    Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma

    phase 1 other active

    1 trial
  24. R4-FOUR-PET

    Fondazione Telethon ETS

    Advanced solid neoplasm (breast, lung, colon, ovary, pancreas) characterized by positive CXCR4 expression by immunohistochemistry

    phase 1 other active

    1 trial
  25. R5054-ONC-1843

    Lacuna Pharma Pty Ltd

    Advanced Solid Tumor

    phase 1 other active

    1 trial
  26. R6569-ONC-1933

    Lacuna Pharma Pty Ltd

    Squamous Cell Carcinoma of Head and Neck

    phase 1 other active

    1 trial
  27. RAD 001 in combination with Caelyx

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial
  28. RBL001/RBL002

    Atrium Therapeutics

    Melanoma

    phase 1 mab completed

    1 trial
  29. REGN1400

    Regeneron UK Limited

    Cancer

    phase 1 small molecule completed

    1 trial
  30. REGN2810

    Regeneron UK Limited

    Melanoma

    phase 1 small molecule completed

    1 trial
  31. REGN2810

    Regeneron UK Limited

    Recurrent Squamous Cell Carcinoma of Head

    phase 1 small molecule completed

    1 trial
  32. REGN4659

    Regeneron UK Limited

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule terminated

    1 trial
  33. REGN5678

    Regeneron UK Limited

    Prostate Cancer

    phase 1 small molecule active

    1 trial
  34. REGN6569

    Regeneron UK Limited

    Squamous Cell Carcinoma of Head and Neck

    phase 1 small molecule terminated

    1 trial
  35. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    Muscle-invasive Transitional Cell Carcinoma of the Bladder

    phase 1 mab terminated

    1 trial
  36. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    KRAS Mutant Metastatic Colorectal Cancer

    phase 1 mab completed

    1 trial
  37. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    Pancreatic Adenocarcinoma

    phase 1 mab completed

    1 trial
  38. RESTART; Autologous Transplantation of Adult...

    Disc Medicine

    Patients operated with curative intend for head and neck cancer with an indication for bilateral postoperative radiotherapy, with or without chemotherapy.

    phase 1 other active

    1 trial
  39. RJMty19 (CD19-CAR-DNT cells)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    B-cell Non-Hodgkin's Lymphoma

    phase 1 mab active

    1 trial
  40. RMC-4630

    Revolution Medicines

    Solid Tumors

    phase 1 small molecule active

    1 trial
  41. RMC-5127

    Revolution Medicines

    Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial
  42. RMC-5552

    Revolution Medicines

    Solid Tumors

    phase 1 small molecule completed

    1 trial
  43. RMC-6291

    Revolution Medicines

    Non-Small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    2 trials
  44. RMC-6291-001

    Revolution Medicines

    Non-Small Cell Lung Cancer (NSCLC), Pancreatic Ductal Adenocarcinoma, Advanced Solid Tumor, Colorectal Cancer (CRC)

    phase 1 other active

    1 trial
  45. RMC-6291-101

    Revolution Medicines

    Participants with Advanced KRASG12C-Mutated Solid Tumors

    phase 1 other active

    1 trial
  46. RMC-9805

    Revolution Medicines

    Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial
  47. RMC-LUNG-101A

    Revolution Medicines

    Lung Cancer

    phase 1 small molecule active

    1 trial
  48. RMC-LUNG-101B

    Revolution Medicines

    Lung Cancer

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many oncology pipeline programs are tracked?

5,539 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.