Oncology · Phase III

Top sponsors

• AstraZeneca 75 programs
• Chinese Academy of 70 programs
• HOFFMANN-LA ROCHE 68 programs
• MSD Merck Sharp 56 programs
• First People's Hospital 53 programs
• Ningbo Cancer Hospital 44 programs
• United Therapeutics Europe 43 programs
• Anaxis Pharma 37 programs
• AstraZeneca 37 programs
• Novartis India 32 programs
• George Institute for 29 programs
• Takeda 28 programs

1. ALPELISIB for PIK3CA mutated HER2+ advanced o…

   Ningbo Cancer Hospital

   PIK3CA mutated HER2+ advanced or relapsed breast cancer (BC) previously treated with trastuzumab

   phase 3 · small molecule · active

   1 trial →

2. AMG 479

   Takeda

   Adenocarcinoma of the Pancreas

   phase 3 · small molecule · completed

   1 trial →

3. AMG 706

   Takeda

   Non-Small Cell Lung Cancer

   phase 3 · small molecule · terminated

   1 trial →

4. AMG386 plus PLD

   Amgen

   Fallopian Tube Cancer

   phase 3 · small molecule · terminated

   1 trial →

5. APG2575AG301

   Lacuna Pharma Pty Ltd

   Acute myeloid leukemia

   phase 3 · small molecule · active

   1 trial →

6. APG2575CC301

   Lacuna Pharma Pty Ltd

   Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

   phase 3 · small molecule · active

   1 trial →

7. APG2575CG301

   Lacuna Pharma Pty Ltd

   Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

   phase 3 · small molecule · active

   1 trial →

8. APHP220917

   Pari Pharma GmbH

   patient with colorectal cancer with hepatic metastasis

   phase 3 · small molecule · active

   1 trial →

9. APHP231089

   Pari Pharma GmbH

   Multiple Myeloma Multiple myeloma (MM) is a B cell malignancy and is one of the most frequent primary neoplasms of the bone marrow

   phase 3 · small molecule · active

   1 trial →

10. APHP241011

    Pari Pharma GmbH

    Adult patients with stage IV non squamous non-small cell lung cancer (NSCLC)

    phase 3 · small molecule · active

    1 trial →

11. APHP241013

    Pari Pharma GmbH

    Young Adults and adults with R/R B-cell acute lymphoblastic leukemia (BCP-ALL) or a B cell lymphoma (BCL)

    phase 3 · small molecule · active

    1 trial →

12. ARC-10

    Arcus Biosciences

    Squamous Non-small cell Lung Cancer, Non-Small Cell Lung Cancer, Non squamous Non Small Cell Lung Cancer, Lung Cancer

    phase 3 · small molecule · active

    1 trial →

13. ARN-509-003

    Lacuna Pharma Pty Ltd

    Castration-Resistant Prostate Cancer

    phase 3 · small molecule · active

    1 trial →

14. ASCIMINIB HYDROCHLORIDE, ASCIMINIB

    Novartis Pharmaceuticals

    Chronic Myelogenous Leukemia in chronic phase (CML-CP)

    phase 3 · small molecule · active

    1 trial →

15. ASTX030-01

    Taiho Pharma Netherlands B.V.

    Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML)

    phase 3 · small molecule · active

    1 trial →

16. AT148006

    Wuhan Createrna Science and Technology Co., Ltd

    Patients with HER2-overexpressing advanced or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma that has progressed on or after a prior HER2-directed agent and fluoropyrimidine- or platinum-containing chemotherapy (2nd-line or 3rd-line)

    phase 3 · small molecule · active

    1 trial →

17. AU-011-301

    Aura Biosciences

    Primary Indeterminate Lesions or Small Choroidal Melanoma

    phase 3 · small molecule · active

    1 trial →

18. AV-299-23-301

    Lacuna Pharma Pty Ltd

    Head and Neck Squamous Cell Carcinoma (HNSCC)

    phase 3 · small molecule · active

    1 trial →

19. AV-951-20-304

    Lacuna Pharma Pty Ltd

    Renal cell carcinoma

    phase 3 · small molecule · active

    1 trial →

20. AZD0901

    AstraZeneca

    Gastric Cancer

    phase 3 · small molecule · active

    2 trials →

21. AZD9291 80 mg/40 mg

    AstraZeneca

    Stage IB-IIIA Non-small Cell Lung Carcinoma

    phase 3 · small molecule · active

    1 trial →

22. Abemaciclib

    United Therapeutics Europe Ltd

    Breast Cancer Female

    phase 3 · small molecule · active

    1 trial →

23. Abemaciclib

    Eli Lilly and Company

    Breast Cancer

    phase 3 · small molecule · active

    1 trial →

24. Abemaciclib

    Eli Lilly and Company

    Non Small Cell Lung Cancer

    phase 3 · small molecule · active

    1 trial →

25. Abiraterone - Usual

    Lxo Ireland Designated Activity Company

    Prostate Cancer

    phase 3 · small molecule · active

    1 trial →

26. Acalabrutinib

    AstraZeneca

    Untreated Chronic Lymphocytic Leukemia

    phase 3 · small molecule · active

    1 trial →

27. Active CTC Assessment

    United Therapeutics Europe Ltd

    Adenocarcinoma of the Prostate

    phase 3 · other · terminated

    1 trial →

28. Active Surveillance

    Blackmores Limited

    Muscle-Invasive Bladder Carcinoma

    phase 3 · other · active

    1 trial →

29. Adjuvant immunotherapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nasopharyngeal Carcinoma

    phase 3 · small molecule · active

    1 trial →

30. Afatinib

    Boehringer Ingelheim

    Head and Neck Neoplasms

    phase 3 · small molecule · completed

    1 trial →

31. Afinitor 5 mg tablets, PLACEBO

    Ningbo Cancer Hospital

    Patients with high risk of relapse, ER+ and HER2- primary non-metastatic breast cancer who remain disease-free

    phase 3 · small molecule · active

    1 trial →

32. Aflibercept

    Regeneron UK Limited

    Colorectal Cancer Metastatic

    phase 3 · small molecule · completed

    3 trials →

33. Aflibercept

    Regeneron UK Limited

    Prostatic Neoplasms

    phase 3 · small molecule · completed

    1 trial →

34. Aflibercept AVE0005

    Regeneron UK Limited

    Colorectal Cancer Metastatic

    phase 3 · small molecule · terminated

    2 trials →

35. Aglatimagene besadenovec + valacyclovir

    Candel Therapeutics

    Prostate Cancer

    phase 3 · mab · active

    1 trial →

36. Alectinib

    Hoffmann-La Roche

    Non-Small Cell Lung Cancer

    phase 3 · small molecule · active

    1 trial →

37. Alectinib - Usual

    Lxo Ireland Designated Activity Company

    ALK-Positive Non-Small Cell Lung Cancer (NSCLC)

    phase 3 · small molecule · active

    1 trial →

38. Alisertib

    Takeda

    Relapsed Peripheral T-Cell Lymphoma

    phase 3 · small molecule · completed

    1 trial →

39. Almonertinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-small Cell Lung Cancer Metastatic

    phase 3 · small molecule · active

    1 trial →

40. Amivantamab

    Janssen Cilag International NV

    Colorectal Neoplasms

    phase 3 · mab · active

    1 trial →

41. Anastrozole

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 3 · small molecule · active

    2 trials →

42. Anti-PD-1 antibody drug named Serplulimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Locally Advanced Rectal Cancer (LARC)

    phase 3 · small molecule · active

    1 trial →

43. Apalutamide

    Janssen Cilag International NV

    Metastatic Castrate-sensitive Prostate Cancer

    phase 3 · small molecule · active

    1 trial →

44. Aromatase Inhibitors

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 3 · small molecule · active

    1 trial →

45. Arsenic trioxide

    Teva Pharma GmbH

    Acute Myeloid Leukemia

    phase 3 · small molecule · terminated

    1 trial →

46. Arsenic trioxide

    Teva Pharma GmbH

    Acute Promyelocytic Leukemia

    phase 3 · small molecule · completed

    1 trial →

47. Asciminib

    Novartis Pharmaceuticals

    Chronic Myelogenous Leukemia

    phase 3 · small molecule · completed

    1 trial →

48. Asparaginase

    Children's Hospital of Fudan University

    Acute Myeloid Leukemia

    phase 3 · small molecule · active

    1 trial →

Frequently asked questions