Oncology · Phase III

Top sponsors

• AstraZeneca 75 programs
• Chinese Academy of 70 programs
• HOFFMANN-LA ROCHE 68 programs
• MSD Merck Sharp 56 programs
• First People's Hospital 53 programs
• Ningbo Cancer Hospital 44 programs
• United Therapeutics Europe 43 programs
• Anaxis Pharma 37 programs
• AstraZeneca 37 programs
• Novartis India 32 programs
• George Institute for 29 programs
• Takeda 28 programs

1. KT-US-473-0133

   Lacuna Pharma Pty Ltd

   Relapsed/Refractory Follicular Lymphoma

   phase 3 · small molecule · active

   1 trial →

2. L-leucovorin

   United Therapeutics Europe Ltd

   Colorectal Cancer

   phase 3 · small molecule · completed

   1 trial →

3. LHRHa

   Janssen Cilag International NV

   Prostatic Neoplasms

   phase 3 · small molecule · active

   1 trial →

4. LI

   Teva Pharma GmbH

   Squamous Cell Carcinoma of the Oral Cavity

   phase 3 · mab · completed

   1 trial →

5. LIBTAYO 350 mg concentrate for solution for infusion.

   Partner Therapeutics Limited

   Patients with resected stage II-IIIA non-small cell lung cancer (NSCLC) with PD-L1 expression ≥1%

   phase 3 · small molecule · active

   1 trial →

6. LORLATINIB

   Pfizer Australia Pty Ltd

   Advanced ALK positive non-small cell lung cancer

   phase 3 · small molecule · active

   1 trial →

7. LOXO-BTK-20019

   Wuhan Createrna Science and Technology Co., Ltd

   Mantle cell lymphoma

   phase 3 · small molecule · active

   1 trial →

8. LOXO-BTK-20020

   Wuhan Createrna Science and Technology Co., Ltd

   Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

   phase 3 · small molecule · active

   1 trial →

9. LOXO-BTK-20022

   Wuhan Createrna Science and Technology Co., Ltd

   Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)

   phase 3 · small molecule · active

   1 trial →

10. LOXO-BTK-20023

    Wuhan Createrna Science and Technology Co., Ltd

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

    phase 3 · small molecule · active

    1 trial →

11. LOXO-BTK-20030

    Wuhan Createrna Science and Technology Co., Ltd

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

    phase 3 · small molecule · active

    1 trial →

12. LV305

    Lxo Ireland Designated Activity Company

    Synovial Sarcoma

    phase 3 · mab · terminated

    1 trial →

13. Lapatinib

    GlaxoSmithKline

    Neoplasms, Head and Neck

    phase 3 · small molecule · completed

    1 trial →

14. Lapatinib

    Novartis Pharmaceuticals

    Neoplasms, Breast

    phase 3 · small molecule · terminated

    2 trials →

15. Lapatinib

    Novartis Pharmaceuticals

    Breast Neoplasms

    phase 3 · small molecule · completed

    1 trial →

16. Lenalidomide

    Celgene Europe Limited

    B-cell Chronic Lymphocytic Leukemia

    phase 3 · small molecule · completed

    1 trial →

17. Lenvatinib

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma

    phase 3 · small molecule · terminated

    1 trial →

18. Lenvatinib

    Merck KGaA, Darmstadt, Germany

    Carcinoma, Hepatocellular

    phase 3 · small molecule · completed

    1 trial →

19. Lerotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Esophageal Cancer

    phase 3 · small molecule · active

    1 trial →

20. Leuprorelin

    Takeda

    Prostate Cancer

    phase 3 · small molecule · completed

    1 trial →

21. Leuprorelin SR

    Takeda

    Prostatic Neoplasms, Locally Advanced

    phase 3 · small molecule · completed

    1 trial →

22. Levotiroxina Teva 25 microgrammi compresse

    Fondazione Telethon ETS

    Hodgkin and non Hodgkin lymphoma, Medulloblastoma

    phase 3 · small molecule · active

    1 trial →

23. Lifileucel plus Pembrolizumab

    Iovance Biotherapeutics B.V.

    Metastatic Melanoma

    phase 3 · mab · active

    1 trial →

24. Loncastuximab Tesirine

    ADC Therapeutics SA

    Relapsed Diffuse Large B-Cell Lymphoma

    phase 3 · small molecule · active

    1 trial →

25. Luveltamab tazevibulin

    SUTRO BIOPHARMA, INC.

    Ovarian Cancer

    phase 3 · small molecule · terminated

    1 trial →

26. Lynparza film-coated tablets for Recurrent ovarian cancer

    Fondazione Telethon ETS

    Recurrent ovarian cancer

    phase 3 · small molecule · active

    1 trial →

27. M15-656

    AbbVie Deutschland GmbH & Co. KG

    Acute Myeloid Leukemia

    phase 3 · small molecule · active

    1 trial →

28. M16-043

    AbbVie Deutschland GmbH & Co. KG

    Acute Myeloid Leukemia

    phase 3 · small molecule · active

    1 trial →

29. M19-708

    AbbVie Deutschland GmbH & Co. KG

    Acute Myeloid Leukemia in First Remission

    phase 3 · small molecule · active

    1 trial →

30. M20-621

    AbbVie Deutschland GmbH & Co. KG

    Diffuse Large B-Cell Lymphoma (DLBCL)

    phase 3 · small molecule · active

    1 trial →

31. M20-638

    AbbVie Deutschland GmbH & Co. KG

    Relapsed and Refractory Follicular Lymphoma

    phase 3 · small molecule · active

    1 trial →

32. M22-003

    AbbVie Deutschland GmbH & Co. KG

    Follicular Lymphoma

    phase 3 · small molecule · active

    1 trial →

33. M22-128

    AbbVie Deutschland GmbH & Co. KG

    Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

    phase 3 · small molecule · active

    1 trial →

34. M23-721

    AbbVie Deutschland GmbH & Co. KG

    Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer, Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer, Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer, Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer

    phase 3 · small molecule · active

    1 trial →

35. M24-052

    AbbVie Deutschland GmbH & Co. KG

    Metastatic Hepatocellular Carcinoma (HCC)

    phase 3 · small molecule · active

    1 trial →

36. M24-064

    AbbVie Deutschland GmbH & Co. KG

    Metastatic Colorectal Cancer

    phase 3 · small molecule · active

    1 trial →

37. M24-287

    AbbVie Deutschland GmbH & Co. KG

    Chronic Lymphocytic Leukemia

    phase 3 · small molecule · active

    1 trial →

38. M25-287

    AbbVie Deutschland GmbH & Co. KG

    Non-Squamous Non-Small Cell Lung Cancer

    phase 3 · small molecule · active

    1 trial →

39. M25-713

    AbbVie Deutschland GmbH & Co. KG

    Non-Small Cell Lung Cancer

    phase 3 · small molecule · active

    1 trial →

40. MB-108

    Moleculin Biotech

    Acute Myeloid Leukemia

    phase 3 · small molecule · active

    1 trial →

41. MB11-C-01-25

    Mabxience Research SL

    Previously Untreated Advanced (Unresectable or Metastatic) Melanoma

    phase 3 · small molecule · active

    1 trial →

42. MB12-C-02-24

    Mabxience Research SL

    advanced/metastatic non-squamous non-small cell lung cancer (NSCLC)

    phase 3 · other · active

    1 trial →

43. MEDI4736

    AstraZeneca

    Squamous Cell Carcinoma of the Head and Neck

    phase 3 · mab · completed

    1 trial →

44. MEDI4736

    AstraZeneca

    Non-Small Cell Lung Cancer

    phase 3 · small molecule · completed

    1 trial →

45. MEDI4736 (Durvalumab)

    AstraZeneca

    Non-Small-Cell Lung Carcinoma NSCLC

    phase 3 · mab · active

    1 trial →

46. MEDI4736 Placebo, DURVALUMAB

    CERO THERAPEUTICS HOLDINGS, INC.

    Completely resected primary stage IB (≥ 4cm), II and IIIA non-small cell lung cancer patients

    phase 3 · small molecule · active

    1 trial →

47. MEDOPP545

    Stemline Therapeutics B.V.

    patients with estrogen receptor-positive/human epidermal growth factor receptor 2-negative, ESR1-mutated, advanced breast cancer progressing to endocrine therapy and CDK4/6 inhibitors.

    phase 3 · small molecule · active

    1 trial →

48. MEP

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nasopharyngeal Carcinoma

    phase 3 · small molecule · terminated

    1 trial →

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