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Metabolic & obesity · Phase I

Metabolic & obesity programs at Phase I — ClinicalTrials.gov pipeline intelligence.

Programs
159

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Metabolic & obesity Phase I programs: NovaPharmaNews indexes 159 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

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  1. A study of how CagriSema works on appetite in people with excess body weight

    NovoThirteen

    Obesity

    phase 1 other active

    1 trial

  2. A study to assess the pharmacokinetics, and glucodynamics of LY3209590 in participants with type 2 diabetes

    Eli Lilly Co.

    Type 2 Diabetes Mellitus

    phase 1 other active

    1 trial

  3. A study to see the effect of NNC0194-0499 alone or in combination with semaglutide on blood sugar control in people living with type 1 diabetes.

    NovoThirteen

    Diabetes mellitus type 1

    phase 1 other active

    1 trial

  4. A study to test how a new long-acting insulin works in the body of patients with type 2 diabetes during exercise and prolonged fasting.

    NovoThirteen

    Type 2 diabetes

    phase 1 other active

    1 trial

  5. A study to test how insulin NNC0471-0119 H works in the body in participants with type 1 diabetes when given by an insulin pump.

    NovoThirteen

    Diabetes mellitus type 1

    phase 1 other active

    1 trial

  6. A study to test how insulin NNC0471-0119 works in the body in participants with type 2 diabetes when given by an insulin pump.

    NovoThirteen

    Diabetes mellitus type 2

    phase 1 other active

    1 trial

  7. A study to test how well different doses of BI 3034701 are tolerated by healthy men and people with overweight or obesity

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  8. A study to test how well different doses of BI 3804379 are tolerated by healthy people and patients with MASH

    Boehringer Ingelheim

    Metabolic Dysfunction-associated Steatohepatitis

    phase 1 other active

    1 trial

  9. A study to test whether BI 456906 (survodutide) influences the amount of bupropion, caffeine and midazolam in the blood in people with overweight or obesity

    Boehringer Ingelheim

    Overweight, Obesity

    phase 1 other active

    1 trial

  10. A study to test whether multiple doses of BI 456906 have an effect on cardiac safety in people with overweight or obesity.

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  11. ALG-055009

    Aligos Therapeutics

    NASH - Nonalcoholic Steatohepatitis

    phase 1 small molecule completed

    1 trial

  12. ALN-PNP

    Regeneron UK Limited

    Nonalcoholic Fatty Liver Disease (NAFLD)

    phase 1 small molecule completed

    1 trial

  13. ALT-801

    Timmune Biotech

    Obesity

    phase 1 small molecule completed

    1 trial

  14. Administration of UI087

    United Therapeutics Europe Ltd

    Diabetes Mellitus (Type 2)

    phase 1 small molecule active

    1 trial

  15. An open label, balanced, randomized, single dose, two treatment, two period, two sequence, crossover, bioequivalence study comparing Empagliflozin Tablets 25 mg, manufactured by Sun Pharmaceutical Industries Limited, India with Jardiance (Empagliflozin) 25 mg film-coated tablets, Marketing Authorisation Holder Boehringer Ingelheim International GmbH Binger Strasse 173 55216 Ingelheim am Rhein Germany, in healthy adult, human subjects under fasting condition.

    Lacuna Pharma Pty Ltd

    Diabetes

    phase 1 other active

    1 trial

  16. Aramchol

    Galmed Pharmaceuticals

    NASH

    phase 1 small molecule completed

    1 trial

  17. Autologous differentiated myocyte transplantation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metabolic Disease

    phase 1 mab active

    1 trial

  18. BCX7353 and probes

    Biocryst

    Hereditary Angioedema

    phase 1 small molecule completed

    1 trial

  19. Bioequivalence clinical trial of dapagliflozin 10 mg tablets, after a single oral dose administration to healthy volunteers under fasting conditions.

    Laboratorios Tillomed Spain S.L.U

    Diabetes

    phase 1 other active

    1 trial

  20. Busulfan Fresenius Kabi 6 mg/ml concentrate for solution for infusion, Neupogen 30 MU (0,6 mg/ml) solución inyectable en jeringa precargada filgrastim, Mozobil 20 mg/ml solution for injection, Merilen

    Lacuna Pharma Pty Ltd

    Inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells, Pyruvate Kinase Deficiency

    phase 1 small molecule active

    1 trial

  21. C19-A3 GNP

    Cardiff Oncology

    Type 1 Diabetes

    phase 1 small molecule completed

    1 trial

  22. CKD-371

    Hong Kong Baptist University

    Type II Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  23. CKD-393 formulation I

    Hong Kong Baptist University

    Type II Diabetes

    phase 1 small molecule completed

    1 trial

  24. CM-101

    Chemomab Therapeutics

    Nonalcoholic Steatohepatitis (NASH)

    phase 1 small molecule completed

    1 trial

  25. CRB-913

    Corbus Pharmaceuticals Holdings

    Obese But Otherwise Healthy Participants

    phase 1 small molecule active

    1 trial

  26. CT-996

    The First People's Hospital of Lianyungang

    Type 2 Diabetes

    phase 1 small molecule completed

    1 trial

  27. Camel milk containing Bifidobacterium animalis A6

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Type 2 Diabetes

    phase 1 other completed

    1 trial

  28. Clinical research trial for evaluating different properties, such as safety, tolerability and body interaction, of a new drug called ALY688ER, administered as subcutaneous injection in healthy overweight or obese people.

    Lacuna Pharma Pty Ltd

    NASH

    phase 1 other active

    1 trial

  29. DFUPS

    United Therapeutics Europe Ltd

    Diabetic Foot

    phase 1 other completed

    1 trial

  30. Dose escalation of SA030

    Suzhou Ribo Life Science Co.

    Obese

    phase 1 small molecule active

    1 trial

  31. Drug 601

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Diabetic Macular Edema

    phase 1 small molecule active

    1 trial

  32. EDP 305

    ENANTA PHARMACEUTICALS INC

    NASH

    phase 1 small molecule completed

    1 trial

  33. EDP 305

    ENANTA PHARMACEUTICALS INC

    Presumptive NAFLD

    phase 1 small molecule completed

    1 trial

  34. EDP-297

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis With Liver Fibrosis

    phase 1 small molecule completed

    1 trial

  35. EDP-305

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 small molecule completed

    2 trials

  36. Empagliflozin 10 MG Oral Tablet [Jardiance]

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  37. Erythromycin lactobionate

    ADIAL PHARMACEUTICALS, INC.

    Diabetes Mellitus, Type 1

    phase 1 small molecule completed

    1 trial

  38. FT-003

    The First People's Hospital of Lianyungang

    Diabetic Macular Edema

    phase 1 gene therapy active

    1 trial

  39. Faster Aspart

    Novo Nordisk A/S

    Diabetes Mellitus, Type 1

    phase 1 small molecule completed

    1 trial

  40. Fluconazole

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 small molecule completed

    1 trial

  41. GR-MD-02

    GALECTIN THERAPEUTICS INC

    Non-Alcoholic Steatohepatitis (NASH)

    phase 1 small molecule completed

    1 trial

  42. Garetosmab

    Regeneron UK Limited

    Obesity

    phase 1 small molecule terminated

    1 trial

  43. Glucagon

    United Therapeutics Europe Ltd

    Type 1 Diabetes Mellitus With Hypoglycemia

    phase 1 small molecule completed

    1 trial

  44. Glucose

    United Therapeutics Europe Ltd

    Diabetes Mellitus

    phase 1 other completed

    1 trial

  45. HEC73077 tablets

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Diabetic Nephropathy

    phase 1 small molecule completed

    1 trial

  46. HEC96719

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Nonalcoholic Steatohepatitis (NASH)

    phase 1 small molecule completed

    1 trial

  47. HEC96719 tablets

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Nonalcoholic Steatohepatitis (NASH)

    phase 1 small molecule completed

    1 trial

  48. HMS5552

    Hua Medicine Limited

    Type II Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many metabolic & obesity Phase I programs exist?

159 programs match both the therapeutic area and stage filters in our published index.

Data attribution: Data sources · All pipeline programs

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