Infectious disease · Phase III

Top sponsors

• United Therapeutics Europe 22 programs
• GSK Glaxo Smith 20 programs
• BRIGHT MINDS BIOSCIENCES 18 programs
• Chinese Academy of 13 programs
• Takeda 12 programs
• Sinovac Research and 11 programs
• Gilead Sciences Ireland 10 programs
• PARItec 10 programs
• Gilead Sciences 9 programs
• Pfizer 8 programs
• Vir Biotechnology 7 programs
• George Institute for 6 programs

1. MGL-3196

   Madrigal Pharmaceuticals EU Limited

   NASH - Nonalcoholic Steatohepatitis

   phase 3 · small molecule · active

   1 trial →

2. MGL-3196-11

   Madrigal Pharmaceuticals EU Limited

   Non-Alcoholic Steatohepatitis (NASH)

   phase 3 · small molecule · active

   1 trial →

3. MGL-3196-19

   Madrigal Pharmaceuticals EU Limited

   Non-alcoholic Steatohepatitis (NASH) Cirrhosis

   phase 3 · small molecule · active

   1 trial →

4. MK-4482-023

   Merck Sharp and Dohme

   SARS-CoV-2 (COVID-19) infection

   phase 3 · small molecule · active

   1 trial →

5. MK-8527

   Merck KGaA, Darmstadt, Germany

   Human Immunodeficiency Virus (HIV)

   phase 3 · small molecule · active

   1 trial →

6. MK-8527-011

   Merck Sharp and Dohme

   HIV-1 prevention

   phase 3 · small molecule · active

   1 trial →

7. MK-8591A

   Merck Sharp and Dohme

   HIV infection

   phase 3 · small molecule · active

   1 trial →

8. MK-8591A-053

   Merck Sharp and Dohme

   HIV-1 Infection

   phase 3 · small molecule · active

   1 trial →

9. MK-8591B-062

   Merck Sharp and Dohme

   HIV

   phase 3 · small molecule · active

   1 trial →

10. MP-424

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 3 · small molecule · completed

    2 trials →

11. MP-424

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 3 · small molecule · completed

    1 trial →

12. Medium-dosage COVID-19 Vaccine,Inactivated

    Sinovac Research and Development Co.,

    COVID-19

    phase 3 · mab · terminated

    1 trial →

13. Mencevax ACWY

    GlaxoSmithKline

    Infections, Meningococcal

    phase 3 · mab · completed

    1 trial →

14. Meningococcal vaccine GSK134612

    GlaxoSmithKline

    Infections, Meningococcal

    phase 3 · mab · completed

    2 trials →

15. Mirasol-treated Fresh Whole Blood

    United Therapeutics Europe Ltd

    Transfusion-Transmitted Infectious Disease

    phase 3 · mab · completed

    1 trial →

16. Molnupiravir

    Merck KGaA, Darmstadt, Germany

    Coronavirus Disease (COVID-19)

    phase 3 · small molecule · active

    2 trials →

17. Motivational interviewing

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 3 · other · completed

    1 trial →

18. NCT02735707

    Disc Medicine

    Respiratory tract infection

    phase 3 · small molecule · active

    1 trial →

19. NGAM-12

    Maze Therapeutics

    Primary infection prophylaxis in patients with chronic lymphocytic leukemia (CLL) and secondary hypogammaglobulinemia.

    phase 3 · small molecule · active

    1 trial →

20. NGAM-16

    Maze Therapeutics

    Prevention of a Major infection in patients with Hypogammaglobulinemia and Autoimmune or Rheumatic Conditions receiving treatment with B-cell depletion therapy.

    phase 3 · small molecule · active

    1 trial →

21. NN9931-4553

    NovoThirteen

    Non-alcoholic steatohepatitis (NASH)

    phase 3 · small molecule · active

    1 trial →

22. Nanocovax

    Biotech Pharmaceutical Co.,

    SARS-CoV-2 Infection

    phase 3 · mab · completed

    1 trial →

23. Niclosamide

    United Therapeutics Europe Ltd

    Covid19

    phase 3 · small molecule · completed

    1 trial →

24. Nimenrix

    GlaxoSmithKline

    Infections, Meningococcal

    phase 3 · mab · completed

    1 trial →

25. OP0595-5

    Lacuna Pharma Pty Ltd

    Complicated urinary tract infection (cUTI) and acute uncomplicated pyelonephritis (AP)

    phase 3 · small molecule · active

    1 trial →

26. OP0595-6

    Lacuna Pharma Pty Ltd

    Complicated urinary tract infection (cUTI), acute uncomplicated pyelonephritis (AP), hospital acquired bacterial pneumonia (HABP), ventilator-associated bacterial pneumonia (VABP), and complicated intra-abdominal infection (cIAI)

    phase 3 · small molecule · active

    1 trial →

27. On-site bundled rapid HIV/HCV testing

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-related Disorders

    phase 3 · other · completed

    1 trial →

28. One4All

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 3 · other · completed

    1 trial →

29. Opaganib

    RedHill Biopharma

    COVID-19

    phase 3 · small molecule · terminated

    2 trials →

30. PCV21

    Sanofi Pasteur

    Pneumococcal Infections

    phase 3 · mab · active

    1 trial →

31. PEG-Interferon a-2b + Ribavirin

    Universal Integrated

    Chronic Hepatitis C Infection in HIV-Infected Persons

    phase 3 · small molecule · completed

    1 trial →

32. PEG-interferon-Alfa-2A

    Hospital Authority, Hong Kong

    Chronic Hepatitis B

    phase 3 · small molecule · active

    1 trial →

33. PF-07321332

    Pfizer

    COVID-19

    phase 3 · small molecule · completed

    2 trials →

34. PRO 2000/5

    United Therapeutics Europe Ltd

    HIV Infections

    phase 3 · small molecule · completed

    1 trial →

35. PRO-nCOV-3001

    Sinovac Research and Development Co.,

    Covid19

    phase 3 · mab · completed

    1 trial →

36. PRO-onCOV-3001

    Sinovac Research and Development Co.,

    COVID-19

    phase 3 · mab · completed

    1 trial →

37. PRO-tnCOV-3003

    Sinovac Research and Development Co.,

    COVID-19

    phase 3 · mab · active

    1 trial →

38. Paeoniflorin + phosphatidylcholine or silymarin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatitis, Autoimmune

    phase 3 · small molecule · terminated

    1 trial →

39. Part A: Upamostat 200 mg

    RedHill Biopharma

    Covid19

    phase 3 · small molecule · terminated

    1 trial →

40. Peer HIV Education Program

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 3 · other · completed

    1 trial →

41. Peer Mentoring Intervention for HCV-Infected IDUs

    BRIGHT MINDS BIOSCIENCES INC.

    Hepatitis C

    phase 3 · other · completed

    1 trial →

42. Peg interferon alpha-2b

    Universal Integrated

    Hepatitis C

    phase 3 · small molecule · terminated

    1 trial →

43. PegIntron (peginterferon alfa-2b)

    Universal Integrated

    Hepatitis C, Chronic

    phase 3 · mab · terminated

    1 trial →

44. Pegylated Interferon Alfa 2a

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 3 · mab · completed

    1 trial →

45. Pegylated Interferon Alfa 2a

    Vertex Pharmaceuticals (Australia) Pty.

    Infection

    phase 3 · small molecule · terminated

    1 trial →

46. Permethrin, InfectoScab® 5 % Crème

    Alphapharm Pty Ltd

    Scabies

    phase 3 · small molecule · active

    1 trial →

47. Pioglitazone

    Takeda

    HIV-Associated Lipodystrophy Syndrome

    phase 3 · small molecule · terminated

    1 trial →

48. Placebo

    Tobira Therapeutics

    Nonalcoholic Steatohepatitis

    phase 3 · small molecule · terminated

    1 trial →

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