Neurology & CNS · Phase III

Top sponsors

• HOFFMANN-LA ROCHE 21 programs
• Teva Pharma 12 programs
• Novartis India 10 programs
• Takeda 10 programs
• Bristol-Myers Squibb Australia 9 programs
• Jazz Pharmaceuticals Ireland 7 programs
• Biogen 6 programs
• TG THERAPEUTICS 6 programs
• Acadia Pharmaceuticals 5 programs
• Anaxis Pharma 5 programs
• NEUROCRINE BIOSCIENCES 5 programs
• SUPERNUS PHARMACEUTICALS 5 programs

1. KW-6500

   KYOWA KIRIN AUSTRALIA PTY LTD

   Parkinson's Disease

   phase 3 · small molecule · completed

   1 trial →

2. KY2025-328-02

   The First People's Hospital of Lianyungang

   Post-stroke Epilepsy

   phase 3 · small molecule · active

   1 trial →

3. Ketanest-S 25 Multi-dose for Non-psychotic therapy resistant…

   Disc Medicine

   Non-psychotic therapy resistant unipolar depression

   phase 3 · small molecule · active

   1 trial →

4. LB-102

   LB PHARMACEUTICALS INC

   Schizophrenia

   phase 3 · small molecule · active

   4 trials →

5. LB-102 (50 mg tablet)

   LB PHARMACEUTICALS INC

   Schizophrenia

   phase 3 · small molecule · active

   1 trial →

6. LECANEMAB

   Eisai Co.,

   Early Preclinical Alzheimer’s Disease and Intermediate Amyloid, Preclinical Alzheimer’s Disease and Elevated Amyloid

   phase 3 · small molecule · active

   1 trial →

7. Laquinimod

   Teva Pharma GmbH

   Multiple Sclerosis

   phase 3 · small molecule · completed

   3 trials →

8. Laquinimod

   Teva Pharma GmbH

   Relapsing Remitting Multiple Sclerosis

   phase 3 · small molecule · terminated

   2 trials →

9. Laquinimod

   Teva Pharma GmbH

   Relapsing Multiple Sclerosis

   phase 3 · small molecule · terminated

   2 trials →

10. Lecanemab

    Eisai Co.,

    Mild cognitive impairment due to Alzheimer's disease or mild Alzheimer's disease dementia.

    phase 3 · small molecule · active

    1 trial →

11. Levetiracetam

    UCB Pharma

    Epilepsy

    phase 3 · small molecule · completed

    1 trial →

12. Levetiracetam NORMON comprimidos recubiertos...

    The George Institute

    Down syndrome, Alzheimer's Disease

    phase 3 · small molecule · active

    1 trial →

13. Levodopa-Carbidopa Intestinal Gel (LCIG)

    AbbVie

    Advanced Parkinson's Disease

    phase 3 · small molecule · completed

    1 trial →

14. Lu AF35700

    H. Lundbeck A/S

    Treatment-resistant Schizophrenia

    phase 3 · small molecule · terminated

    1 trial →

15. Lurasidone

    Sumitomo Pharma (Suzhou) Co.,

    Bipolar I Depression

    phase 3 · small molecule · completed

    1 trial →

16. MN39158

    Hoffmann-La Roche

    Multiple sclerosis (MS)

    phase 3 · small molecule · active

    1 trial →

17. MN39159

    Hoffmann-La Roche

    Progressive multiple sclerosis (PMS)

    phase 3 · small molecule · active

    1 trial →

18. MN45053

    Hoffmann-La Roche

    Multiple Sclerosis

    phase 3 · small molecule · active

    1 trial →

19. MN45053

    Hoffmann-La Roche

    Neurological Disease

    phase 3 · small molecule · active

    1 trial →

20. MYL-1603N-3001

    Mylan Pharma UK

    Major Depression Disorder

    phase 3 · small molecule · active

    1 trial →

21. MYL-1603N-3002

    Mylan Pharma UK

    Major Depression Disorders

    phase 3 · small molecule · active

    1 trial →

22. Matched placebo for product, Frexalimab

    Sanofi-aventis Healthcare Pty Ltd

    Multiple sclerosis

    phase 3 · small molecule · active

    1 trial →

23. N01269

    Lacuna Pharma Pty Ltd

    Childhood Absence Epilepsy Juvenile Absence Epilepsy

    phase 3 · small molecule · active

    1 trial →

24. NA_00090926

    United Therapeutics Europe Ltd

    TBI Depression

    phase 3 · other · completed

    1 trial →

25. NBI-1117568

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia

    phase 3 · small molecule · active

    5 trials →

26. NBI-1117568, NBI-1117568

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia, Schizophrenia

    phase 3 · small molecule · active

    1 trial →

27. NBI-1117568-SCZ3030

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia

    phase 3 · small molecule · active

    1 trial →

28. NBI-98854-ATS3019

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia

    phase 3 · small molecule · active

    1 trial →

29. NGAM-13

    Maze Therapeutics

    Pediatric acute-onset neuropsychiatric syndrome (PANS)

    phase 3 · small molecule · active

    1 trial →

30. NN6535-4725

    NovoThirteen

    Mild cognitive impairment (MCI) or mild dementia, both of the Alzheimer’s type

    phase 3 · small molecule · active

    1 trial →

31. NN6535-4730

    NovoThirteen

    Mild cognitive impairment (MCI) or mild dementia, both of the Alzheimer’s type

    phase 3 · small molecule · active

    1 trial →

32. NN6535-7519

    NovoThirteen

    Mild cognitive impairment (MCI) or mild dementia, both of the Alzheimer’s type

    phase 3 · small molecule · active

    1 trial →

33. NW-3509/023/III/2024

    Lacuna Pharma Pty Ltd

    treatment-resistant schizophrenia (TRS)

    phase 3 · small molecule · active

    1 trial →

34. NXPLEVE/24/P3-6

    NEURAXPHARM AUSTRALIA PTY LIMITED

    Refractory Partial Onset Epilepsy

    phase 3 · small molecule · active

    1 trial →

35. Nabilone

    BRIGHT MINDS BIOSCIENCES INC.

    Alzheimer Disease

    phase 3 · small molecule · active

    1 trial →

36. Nabiximols

    Jazz Pharmaceuticals Ireland Limited

    Spasticity in Participants With Multiple Sclerosis

    phase 3 · small molecule · completed

    1 trial →

37. Nabiximols

    Jazz Pharmaceuticals Ireland Limited

    Spasticity With Multiple Sclerosis

    phase 3 · small molecule · terminated

    1 trial →

38. Nabiximols

    Jazz Pharmaceuticals Ireland Limited

    Multiple Sclerosis (MS)

    phase 3 · small molecule · terminated

    1 trial →

39. Ocrelizumab

    Hoffmann-La Roche

    Multiple Sclerosis, Primary Progressive

    phase 3 · small molecule · active

    1 trial →

40. Ocrelizumab IV

    Hoffmann-La Roche

    Relapsing Multiple Sclerosis

    phase 3 · small molecule · completed

    1 trial →

41. Ocrevus 300 mg concentrate for solution for infusion

    Hoffmann-La Roche

    Multiple Sclerosis (MS)

    phase 3 · small molecule · active

    1 trial →

42. Orelabrutinib

    Zenas BioPharma

    Secondary Progressive Multiple Sclerosis

    phase 3 · small molecule · active

    1 trial →

43. Orelabrutinib

    Zenas BioPharma

    Multiple Sclerosis (MS) Primary Progressive

    phase 3 · small molecule · active

    1 trial →

44. Oxcarbazepine XR

    SUPERNUS PHARMACEUTICALS, INC.

    Partial Epilepsy

    phase 3 · small molecule · completed

    1 trial →

45. PRAX-628-322

    Chongqing Precision Biotech Co., Ltd

    Focal Epilepsy

    phase 3 · small molecule · active

    1 trial →

46. PROTO-BRAIN

    Tour Hekla

    Resistant Depression in the Elderly Subject

    phase 3 · small molecule · active

    1 trial →

47. Paliperidone palmitate

    Janssen Cilag International NV

    Schizophrenia

    phase 3 · small molecule · completed

    2 trials →

48. Phase 1: Olanzapine

    Shanghai Mental Health Center

    Schizophrenia

    phase 3 · small molecule · completed

    1 trial →

Frequently asked questions