Wednesday, June 10, 2026

Drug profile · INN

raltitrexed

raltitrexed (TOMUDEX) is a thymidylate synthase inhibitor. Associated with Pfizer Australia Pty Ltd.

TGA: approved NMPA: clinical trials
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — raltitrexed

Quick answer

raltitrexed (TOMUDEX) is a thymidylate synthase inhibitor. Associated with Pfizer Australia Pty Ltd.

Key facts

INN raltitrexed
Brand TOMUDEX
Mechanism Thymidylate synthase inhibitor
Target Thymidylate synthase

Mechanism of action

Thymidylate synthase inhibitor

Primary target: Thymidylate synthase

Approval history

Authority Status Date
TGA approved
NMPA clinical trials

Pipeline programs

  1. Raltitrexed Phase 2 · First People's Hospital · Inoperable Esophageal Cancer Stage I-III
  2. raltitrexed combined with apatinib Phase 2 · Chinese PLA General · Colorectal Cancer
  3. Raltitrexed Approved · First People's Hospital · Head and Neck Squamous Cell Carcinoma

Related & competitor drugs

  1. floxuridine Thymidylate synthase inhibitor
  2. pyrimethamine Dihydrofolate reductase inhibitor
  3. flucytosine Thymidylate synthase inhibitor

Frequently asked questions

What is raltitrexed?

raltitrexed (TOMUDEX) is a thymidylate synthase inhibitor. Associated with Pfizer Australia Pty Ltd.

What is the brand name for raltitrexed?

TOMUDEX is a marketed brand name for raltitrexed. Check FDA Drugs@FDA for the current US label holder and prescribing information.