Wednesday, June 10, 2026

Drug profile · INN

nitroglycerin

nitroglycerin (GONITRO) is a soluble guanylate cyclase activator. Associated with Regeneron Ireland Designated Activity Company (DAC). Route of administration: intra-anal. Current US regulatory status: approved.

FDA: approved NMPA: clinical trials
US status approved
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — nitroglycerin
US status
approved
Class
Route
INTRA-ANAL
Patents
0
Programs
5
Data quality
0.89

Quick answer

nitroglycerin (GONITRO) is a soluble guanylate cyclase activator. Associated with Regeneron Ireland Designated Activity Company (DAC). Route of administration: intra-anal. Current US regulatory status: approved.

Key facts

INN nitroglycerin
Brand GONITRO
Mechanism Soluble guanylate cyclase activator
Target Soluble guanylate cyclase
Route INTRA-ANAL
Formulation TABLET

Mechanism of action

Soluble guanylate cyclase activator

Primary target: Soluble guanylate cyclase

Approval history

Authority Status Date
FDA approved
NMPA clinical trials

Pipeline programs

  1. Glycerin Suppository Phase 3 · United Therapeutics Europe · Encopresis
  2. MPs Phase 3 · Chinese Academy of · Hematological Diseases
  3. T89-08-ORESA Phase 3 · Anaxis Pharma · Stable Angina Pectoris
  4. sublingual nitroglycerine Phase 2 · United Therapeutics Europe · COLIC
  5. 22597 Phase 1 · Bayer · Chronic kidney disease, Coronary artery disease

Related & competitor drugs

  1. isosorbide dinitrate Soluble guanylate cyclase activator
  2. isosorbide mononitrate Soluble guanylate cyclase activator
  3. riociguat Cardiovascular system (C02)
  4. sodium nitroprusside Soluble guanylate cyclase activator
  5. nitric oxide Respiratory system (R07)
  6. vericiguat Cardiovascular system (C01)

Frequently asked questions

What is nitroglycerin?

nitroglycerin (GONITRO) is a soluble guanylate cyclase activator. Associated with Regeneron Ireland Designated Activity Company (DAC). Route of administration: intra-anal. Current US regulatory status: approved.

What is the brand name for nitroglycerin?

GONITRO is a marketed brand name for nitroglycerin. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of nitroglycerin?

nitroglycerin has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.