Wednesday, June 10, 2026

pharma Β· Carcinoma, Non-small-cell Lung Β· Type 2 Diabetes Mellitus Β· LGND

LIGAND PHARMACEUTICALS

LIGAND PHARMACEUTICALS patent portfolio β€” 133 USPTO pharmaceutical patents (A61K/A61P) with grant dates, status, and loss-of-exclusivity filters.

555 Heritage Dr, Suite 200, Jupiter, Florida 33458, US HQ
1987 Founded
130 Employees
Public company Type
LGND Β· NYSE Ticker
Company details
Status
Public
HQ
555 Heritage Dr, Suite 200, Jupiter, Florida 33458, US
Founded
1987
Employees
130
Programs
34
Drugs
25
Patents
133
Intelligence Β· Patents

LIGAND PHARMACEUTICALS patents

133 pharmaceutical patents indexed for LIGAND PHARMACEUTICALS. 12 expire within 24 months.

LIGAND PHARMACEUTICALS has 133 pharmaceutical patents in our USPTO PatentsView index (A61K/A61P). 12 expire within 24 months β€” use filters for patent-cliff planning.

Patent portfolio

Page 3 of 3
  1. US 6521657

    Thio-oxindole derivatives

    Expires Mon Feb 13 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  2. US 6509334

    Cyclocarbamate derivatives as progesterone receptor modulators

    Expires Mon Jan 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  3. US 6506766

    Glucocortiocoid-selective antinflammatory agents

    Expires Mon Jan 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  4. US 6503939

    Combination regimens using 3,3-substituted indoline derivatives

    Expires Mon Jan 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  5. US 6498154

    Cyclic regimens using quinazolinone and benzoxazine derivatives

    Expires Mon Dec 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  6. US 6462032

    Cyclic regimens utilizing indoline derivatives

    Expires Mon Oct 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  7. US 6462038

    Androgen receptor modulator compounds and methods

    Expires Mon Oct 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  8. US 6444668

    Combination regimens using progesterone receptor modulators

    Expires Mon Aug 29 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  9. US 6441019

    Cyclocarbamate and cyclic amide derivatives

    Expires Mon Aug 22 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  10. US 6436929

    Cyclothiocarbamate derivatives as progesterone receptor modulators

    Expires Mon Aug 15 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  11. US 6423699

    Combination therapies using benzimidazolones

    Expires Mon Jul 18 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  12. US 6417212

    Modulators of peroxisome proliferator activated receptors

    Expires Mon Jul 04 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  13. US 6417214

    3,3-substituted indoline derivatives

    Expires Mon Jul 04 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  14. US 6413952

    Agonizing dimeric cell-surface receptors with a receptor binding moiety and chelating metal

    Expires Mon Jun 27 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  15. US 6407101

    Cyanopyrroles

    Expires Mon Jun 13 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  16. US 6399593

    Cyclic regimens using cyclic urea and cyclic amide derivatives

    Expires Mon May 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  17. US 6391907

    Indoline derivatives

    Expires Mon May 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  18. US 6380207

    Glucocortiocoid-selective antiinflammatory agents

    Expires Mon Apr 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  19. US 6380235

    Benzimidazolones and analogues

    Expires Mon Apr 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  20. US 6380178

    Cyclic regimens using cyclocarbamate and cyclic amide derivatives

    Expires Mon Apr 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  21. US 6369056

    Cyclic urea and cyclic amide derivatives

    Expires Mon Apr 04 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  22. US 6358947

    Tetracyclic progesterone receptor modulator compounds and methods

    Expires Mon Mar 14 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  23. US 6358948

    Quinazolinone and benzoxazine derivatives as progesterone receptor modulators

    Expires Mon Mar 14 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  24. US 6355648

    Thio-oxindole derivatives

    Expires Mon Mar 07 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  25. US 6339098

    2,1-benzisothiazoline 2,2-dioxides

    Expires Mon Jan 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  26. US 6329416

    Combination regimens using 3,3-substituted indoline derivatives

    Expires Mon Dec 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  27. US 6320074

    Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors

    Expires Mon Nov 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  28. US 6319912

    Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides

    Expires Mon Nov 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  29. US 6316404

    Treating NIDDM with RXR agonists

    Expires Mon Nov 08 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  30. US 6306851

    Cyclocarbamate and cyclic amide derivatives

    Expires Mon Oct 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  31. US 6228862

    Treating NIDDM with RXR agonists

    Expires Mon May 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  32. US 6218430

    Vitamin D3 mimics

    Expires Mon Apr 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  33. US 6211200

    Metal complexes

    Expires Mon Mar 29 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  34. US 6117867

    Substituted 6-R-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetizing, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them

    Expires Mon Sep 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  35. US 6068976

    Modulators of ob gene and screening methods therefor

    Expires Mon May 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  36. US 6028068

    Substituted 6H-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them

    Expires Mon Feb 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  37. US 6028052

    Treating NIDDM with RXR agonists

    Expires Mon Feb 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

How many patents does LIGAND PHARMACEUTICALS have?

133 published patents match the current filter (all indexed). The full portfolio is indexed from USPTO PatentsView (A61K/A61P).

When do LIGAND PHARMACEUTICALS patents expire?

12 patents in the full portfolio expire within 24 months. Use the expiring filters above or open individual patent pages for grant and expiration dates.