Wednesday, June 10, 2026

pharma Β· Hypertriglyceridemia Β· Type 2 Diabetes Mellitus Β· IONS

IONIS PHARMACEUTICALS

IONIS PHARMACEUTICALS patent portfolio β€” 222 USPTO pharmaceutical patents (A61K/A61P) with grant dates, status, and loss-of-exclusivity filters.

2855 Gazelle Ct, Carlsbad, CA 92010, US HQ
1989 Founded
1,493 Employees
Public company Type
IONS Β· NYSE Ticker
Company details
Status
Public
HQ
2855 Gazelle Ct, Carlsbad, CA 92010, US
Founded
1989
Employees
1,493
Programs
128
Drugs
48
Patents
222
Intelligence Β· Patents

IONIS PHARMACEUTICALS patents

222 pharmaceutical patents indexed for IONIS PHARMACEUTICALS. 0 expire within 24 months.

IONIS PHARMACEUTICALS has 222 pharmaceutical patents in our USPTO PatentsView index (A61K/A61P). 0 expire within 24 months β€” use filters for patent-cliff planning.

Patent portfolio

Page 5 of 5
  1. US 9644207

    Compositions and methods for modulating Tau expression

    Expires Mon May 04 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9624496

    Modulation of apolipoprotein C-III expression

    Expires Mon Apr 13 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9617539

    Modulation of UBE3A-ATS expression

    Expires Mon Apr 06 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9617540

    Compounds and methods for modulating gene expression

    Expires Mon Apr 06 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9605259

    Compounds and methods for modulating protein expression

    Expires Mon Mar 23 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9605263

    Compositions for modulating C9ORF72 expression

    Expires Mon Mar 23 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9598693

    Oligomeric compounds and compositions for the use in modulation of micrornas

    Expires Mon Mar 16 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9593333

    Modulation of apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations

    Expires Mon Mar 09 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9574193

    Methods and compositions for modulating apolipoprotein (a) expression

    Expires Mon Feb 16 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9567588

    Modulation of androgen receptor expression

    Expires Mon Feb 09 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9567587

    Antisense modulation of GCCR expression

    Expires Mon Feb 09 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9550988

    Antisense compounds

    Expires Mon Jan 19 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9546368

    Methods for modulating metastasis-associated-in-lung-adenocarcinoma-transcript-1 (MALAT-1) expression

    Expires Mon Jan 12 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9540641

    Cancer treatment

    Expires Mon Jan 05 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9523094

    Methods of treating kennedy's disease

    Expires Mon Dec 15 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9518259

    Compounds and methods for modulating interaction between proteins and target nucleic acids

    Expires Mon Dec 08 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9487780

    Antisense compounds targeting genes associated with fibronectin

    Expires Mon Nov 03 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9476051

    Antisense modulation of superoxide dismutase 1, soluble expression

    Expires Mon Oct 20 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9428750

    Oligomeric compounds comprising tricyclic nucleosides and methods for their use

    Expires Mon Aug 25 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9409934

    Cyclohexenyl nucleic acids analogs

    Expires Mon Aug 04 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9404113

    Antisense modulation of PTP1B expression

    Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9404114

    Antisense modulation of GCGR expression

    Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9399774

    Modulation of transthyretin expression

    Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9365848

    Modulation of apolipoprotein C-III expression

    Expires Mon Jun 09 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9353372

    Compositions and their uses directed to huntingtin

    Expires Mon May 26 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9340784

    Methods and compositions for modulating alpha-1-antitrypsin expression

    Expires Mon May 12 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9322021

    Methods for modulating kallikrein (KLKB1) expression

    Expires Mon Apr 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9321799

    Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

    Expires Mon Apr 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9315811

    Methods for modulating kallikrein (KLKB1) expression

    Expires Mon Apr 14 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9273315

    Modulation of huntingtin expression

    Expires Mon Feb 25 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many patents does IONIS PHARMACEUTICALS have?

222 published patents match the current filter (all indexed). The full portfolio is indexed from USPTO PatentsView (A61K/A61P).

When do IONIS PHARMACEUTICALS patents expire?

0 patents in the full portfolio expire within 24 months. Use the expiring filters above or open individual patent pages for grant and expiration dates.