Intelligence Β· Clinical Pipeline

Disc Medicine Pipeline

All ClinicalTrials.gov programs at Disc Medicine β€” phase, modality, and trial IDs.

Programs
39

Quick answer

Disc Medicine has 39 clinical development programs indexed from ClinicalTrials.gov, including phase, modality, indication text, and linked NCT identifiers.

  1. 68GA-FAPI-46

    Disc Medicine

    Peritoneal metastases

    phase 1 small molecule active

    1 trial
  2. A phase I study investigating the local tolerability and pharmacokinetics of isoniazid (INH) inhalation by wet nebulization in patients with tuberculosis

    Disc Medicine

    Tuberculosis

    phase 1 other active

    1 trial
  3. Adoptive TIL therapy in combination with chemoimmunotherapy in advanced NSCLC patients

    Disc Medicine

    Respiratory tract diseases

    phase 1 other active

    1 trial
  4. AmBisome liposomale amfotericine B 50 mg, poeder voor oplossing voor infusie, TECHNETIUM (99MTC) PERTECHNETATE

    Disc Medicine

    Chronic pulmonary aspergillosis

    phase 1 small molecule active

    1 trial
  5. An open label, phase 1 study to evaluate the safety, feasibility and immunogenicity of an allogeneic, cell-based vaccine (VIDIDENCEL) in high grade serous ovarian cancer patients after primary treatment (ALISON)

    Disc Medicine

    High grade serous ovarian cancer

    phase 1 other active

    1 trial
  6. Bio-equivalence of Rosuvastatin 10 mg

    Disc Medicine

    Healthy volunteers

    phase 1 other active

    1 trial
  7. Click-cleavable imaging in HER2-positive cancers (CleavHER trial).

    Disc Medicine

    HER2-positive tumors

    phase 1 other active

    1 trial
  8. Coadministration of GA2 Sporozoites With Adjuvants (CoGA)

    Disc Medicine

    Falciparum malaria

    phase 1 other active

    1 trial
  9. Combining drug-eluting bead chemoembolization and radioembolization for treatment of colorectal liver metastases: DEBIR90Y study

    Disc Medicine

    colorectal liver metastases

    phase 1 other active

    1 trial
  10. DISC-0974

    Disc Medicine

    Chronic Kidney Diseases

    phase 1 small molecule completed

    1 trial
  11. DISC-0974

    Disc Medicine

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial
  12. DISC-3405

    Disc Medicine

    Sickle Cell Disease

    phase 1 small molecule active

    1 trial
  13. DISC-3405

    Disc Medicine

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial
  14. Dendritic cell therapy combined with surgery in mesothelioma (ENSURE)

    Disc Medicine

    Adult patients diagnosed with resectable epithelioid MPM, following first-line chemotherapy.

    phase 1 other active

    1 trial
  15. Detection of tumor tiSsue in pEritoneal metastases of coLorectal origin using a VEGF-targeted optical fluoresCent imaging tracer during diagnosTic laparoscopy

    Disc Medicine

    peritoneal metastases of colorectal origin

    phase 1 other active

    1 trial
  16. Dual-Wavelength Quantitative Fluorescence Endoscopy for Optical PD-1 and PD-L1 Imaging in Locally Advanced Esophageal Cancer: A Phase I Multicenter Feasibility and Safety Study

    Disc Medicine

    Esophageal cancer

    phase 1 other active

    1 trial
  17. Evaluating PD-1/PD-L1 in rectal cancer by quantitative fluorescence molecular endoscopy.

    Disc Medicine

    Locally advanced rectal cancer

    phase 1 other active

    1 trial
  18. Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104 (HEB-PEP)

    Disc Medicine

    chronic Hepatitis B

    phase 1 other active

    1 trial
  19. GRoningen Early-PD Ambroxol Treatment Pharmacokinetics

    Disc Medicine

    Parkinson's disease

    phase 1 other active

    1 trial
  20. INTERACT MESO: Intraperitoneal Paclitaxel for Patients with Primary Malignant Peritoneal Mesothelioma – a Phase I/II Dose Escalation and Safety Study

    Disc Medicine

    Patients with malignant peritoneal mesothelioma

    phase 1 other active

    1 trial
  21. INTERACT stomach

    Disc Medicine

    Stomach Cancer with metastasis in the peritoneum

    phase 1 other active

    1 trial
  22. Improving Peptide Receptor Radionuclide Therapy with PARP inhibitors

    Disc Medicine

    locally advanced or metastatic, well-differentiated gastro-enteropancreatic neuroendocrine tumors.

    phase 1 other active

    1 trial
  23. Irinotecan Accord 20 mg/ml concentraat voor oplossing voor infusie

    Disc Medicine

    Gastric cancer

    phase 1 small molecule active

    1 trial
  24. MCA-derived MSC therapy in renal transplant recipients

    Disc Medicine

    Rejection transplanted kidney, BPAR

    phase 1 other active

    1 trial
  25. MIRROR; Multispectral and bimodal fluorescent guided surgery (FGS) of high-grade glioma for refining margin assessment: A phase 1 dose finding study using Cetuximab-IRDye800CW- combined with 5-ALA

    Disc Medicine

    Glioblastoma

    phase 1 other active

    1 trial
  26. Molecular imaging with FAPI for diagnosing the CSM4 colorectal cancer subtype

    Disc Medicine

    Colorectal cancer, liver metastases

    phase 1 other active

    1 trial
  27. Optical PD-L1 imaging using Quantitative Fluorescence Endoscopy in locally advanced esophageal cancer using durvalumab-680LT: a phase I multicenter feasibility and safety study

    Disc Medicine

    Esophageal cancer

    phase 1 other active

    1 trial
  28. Oxytocine and migraine

    Disc Medicine

    This is a study in healthy volunteers. We will study the trigeminovascular system, which is relevant in the pathophysiology of migraine.

    phase 1 other active

    1 trial
  29. Pharmacokinetic study of minocycline in patients with nontuberculous mycobacterial disease

    Disc Medicine

    Nontuberculous mycobacterial disease

    phase 1 other active

    1 trial
  30. Phase 0 trial of CBD in recurrent glioblastoma patients

    Disc Medicine

    Glioblastoma

    phase 1 other active

    1 trial
  31. Phase I study of 225Ac-PSMA I&T in prostate cancer

    Disc Medicine

    metastatic prostate cancer

    phase 1 other active

    1 trial
  32. Pilot Study on Subcutaneously Administered Immunotherapy for the Treatment of Cervical Cancer

    Disc Medicine

    Cervical Cancer

    phase 1 other active

    1 trial
  33. RESTART; Autologous Transplantation of Adult Salivary Gland Stem Cells to Restore Submandibular Gland Function after Radiotherapy

    Disc Medicine

    Patients operated with curative intend for head and neck cancer with an indication for bilateral postoperative radiotherapy, with or without chemotherapy.

    phase 1 other active

    1 trial
  34. Repurposed Drugs in Research and Cancer Clinical Trials. The ReDiReCCT trial Vemurafenib

    Disc Medicine

    Glioma

    phase 1 other active

    1 trial
  35. STRATIFY; Near-infrared fluorescence molecular imaging of adalimumab-800CW to elucidate the drug distribution throughout inflamed tissue in inflammatory bowel disease and rheumatoid arthritis

    Disc Medicine

    Crohn's disease, Spondyloarthritis, Rheumatoid arthritis, Ulcerative colitis

    phase 1 other active

    1 trial
  36. Safety of TEG001 in patients with r/r AML/high-risk MDS or r/r MM

    Disc Medicine

    Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Multiple Myeloma (MM)

    phase 1 other active

    1 trial
  37. Takeda Brentuximab; Molecular Imaging of Zirconium-89-labeled Brentuximab as a Tool to Investigate brentuximab biodistribution in CD30-positive Lymphoma

    Disc Medicine

    Patients with stage II-IV high risk diffuse large B-cell lymphoma, defined as international prognostic index > 2, Lymphoma

    phase 1 other active

    1 trial
  38. The detection of tumor-associated fibrosis in colorectal peritoneal metastases by FAPI-PET (TROMPET)

    Disc Medicine

    Metastatic colorectal cancer

    phase 1 other active

    1 trial
  39. Treatment of cancer with Immune Checkpoint Inhibition therapy boosted by High Intensity Focused Ultrasound Histotripsy (the iFOCUS study)

    Disc Medicine

    Metastatic or unresectable solid malignancies. Standard of care treatment options must not be available or not be considered feasible. Patients must have a primary tumor or metastasis that is suitable for HIFU-HT treatment.

    phase 1 other active

    1 trial

Frequently asked questions

How many pipeline programs does Disc Medicine have?

39 published programs are linked to this sponsor in our ClinicalTrials.gov index.

Is this the complete company pipeline?

This hub lists all published programs for the sponsor in our database. Partnered or out-licensed assets may appear under multiple companies.

Data attribution: Data sources Β· All pipeline programs